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- W4301599557 abstract "Use of clips is recommended to mark biopsy-confirmed metastatic axillary lymph nodes before initiation of neoadjuvant chemotherapy (NACT) in breast cancer1–3. In this way, a metastatic node can be localized and followed throughout systemic treatment, and finally biopsied or removed after the completion of NACT4–6. Ultrasound-guided fine-needle aspiration (FNA) is a low-risk procedure that allows quick cytological evaluation of nodal metastases7–9. The present authors10 have demonstrated the accuracy of intraoperative touch imprint cytology in the setting of targeted axillary dissection (TAD) after NACT. Intuitively, there might be a potential use for targeted FNA (TFNA) of a clipped lymph node (CLN) to assess the nodal response before surgery, thus allowing axillary surgery to be tailored and less invasive procedures attempted. The primary goal of this study was to assess the accuracy of post-NACT ultrasound-guided TFNA in predicting residual cancer in the axilla. This prospective single-centre feasibility study included consecutive patients aged above 18 and below 70 years with biopsy-confirmed, clinically T1–4 N1–3 M0 disease. All participants provided written informed consent and were enrolled after study approval by relevant ethics committees." @default.
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- W4301599557 date "2022-08-26" @default.
- W4301599557 modified "2023-09-27" @default.
- W4301599557 title "Accuracy of ultrasound-guided targeted fine-needle aspiration in assessing nodal response in node-positive breast cancer after neoadjuvant chemotherapy: prospective feasibility study" @default.
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- W4301599557 doi "https://doi.org/10.1093/bjs/znac277" @default.
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