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- W4301606343 abstract "Abstract Vedolizumab has a good safety profile for the treatment of inflammatory bowel disease. Agranulocytosis is a rare but fatal condition. Although many drugs are considered to have a high risk of agranulocytosis, no previous study has mentioned vedolizumab. A 71‐year‐old female with Sjogren's syndrome received vedolizumab treatment for moderate to severe ulcerative colitis. Her symptoms improved; however, leukopenia was noted after the first dose. Four days after the second dose, she complained of oral and chest pain. Agranulocytosis, oral candidiasis, and Epstein‐Barr virus esophagitis with ulceration were noted. After granulocyte‐colony stimulating factor treatment, the white blood cell count returned to normal and the esophageal ulcers healed. Vedolizumab is a very safe gut‐selective biologic agent, but it also carries the risk of agranulocytosis." @default.
- W4301606343 created "2022-10-05" @default.
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- W4301606343 date "2022-11-13" @default.
- W4301606343 modified "2023-10-17" @default.
- W4301606343 title "Vedolizumab‐related agranulocytosis with Epstein‐Barr virus esophagitis: A case report" @default.
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- W4301606343 doi "https://doi.org/10.1002/aid2.13342" @default.
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