FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4302016073> ?p ?o ?g. }

• W4302016073 abstract "ABSTARCT Rodent behavior is affected by different environmental conditions. These do not only comprise experimental and housing conditions but also familiarization with the experimenter. However, specific effects on pain-related behavior and chronic pain conditions have not been examined. Therefore, we aimed to investigate the impact of different housing conditions, inverted day-night cycles, and experimenter familiarization on male mice following peripheral neuropathy using the spared nerve injury (SNI) model. Using a multimodal approach, we evaluated evoked pain-related-, anxiety- and depression-like behavior, corticosterone metabolite levels and utilized an integrative approach for relative-severity-assessment. Different environmental conditions are represented by individually ventilated cages and standard open cages combined with a reversed day-night-light cycle and experimenter habituation, inducing differentially modulated multidimensional pain- and emotion-like phenotypes in SNI mice. In addition, familiarization reduced the stress level caused by behavioral tests. Although no environmental condition significantly modulated the severity in SNI mice, it influenced pain-affected phenotypes and is, therefore, crucial for designing and interpreting preclinical pain studies. Moreover, environmental conditions should be considered more in the reporting guidelines, described in more detail, and discussed as a potential influence on pain phenotypes." @default.
• W4302016073 created "2022-10-06" @default.
• W4302016073 creator A5025049560 @default.
• W4302016073 creator A5039166280 @default.
• W4302016073 creator A5046036187 @default.
• W4302016073 creator A5057114218 @default.
• W4302016073 creator A5063994483 @default.
• W4302016073 creator A5085865659 @default.
• W4302016073 creator A5089345616 @default.
• W4302016073 date "2022-10-05" @default.
• W4302016073 modified "2023-10-01" @default.
• W4302016073 title "Experimenter familiarization is a crucial prerequisite for assessing behavioral outcomes and reduces stress in mice not only under chronic pain conditions" @default.
• W4302016073 cites W1965866432 @default.
• W4302016073 cites W1980127085 @default.
• W4302016073 cites W1990891103 @default.
• W4302016073 cites W1999601502 @default.
• W4302016073 cites W2030260413 @default.
• W4302016073 cites W2031168265 @default.
• W4302016073 cites W2041879562 @default.
• W4302016073 cites W2047010161 @default.
• W4302016073 cites W2058020736 @default.
• W4302016073 cites W2063306678 @default.
• W4302016073 cites W2083052804 @default.
• W4302016073 cites W2089680506 @default.
• W4302016073 cites W2095510407 @default.
• W4302016073 cites W2098848290 @default.
• W4302016073 cites W2115262069 @default.
• W4302016073 cites W2134169577 @default.
• W4302016073 cites W2145913238 @default.
• W4302016073 cites W2158978955 @default.
• W4302016073 cites W2166523893 @default.
• W4302016073 cites W2489868682 @default.
• W4302016073 cites W2802438942 @default.
• W4302016073 cites W2886399019 @default.
• W4302016073 cites W2901528734 @default.
• W4302016073 cites W2901694253 @default.
• W4302016073 cites W2909456742 @default.
• W4302016073 cites W2939766012 @default.
• W4302016073 cites W2955204695 @default.
• W4302016073 cites W2998288169 @default.
• W4302016073 cites W3003667387 @default.
• W4302016073 cites W3006731155 @default.
• W4302016073 cites W3036344154 @default.
• W4302016073 cites W3036684916 @default.
• W4302016073 cites W3043135743 @default.
• W4302016073 cites W3109819398 @default.
• W4302016073 cites W3120854869 @default.
• W4302016073 cites W3217099475 @default.
• W4302016073 cites W4200591219 @default.
• W4302016073 cites W4220918557 @default.
• W4302016073 cites W4283011299 @default.
• W4302016073 cites W46255818 @default.
• W4302016073 doi "https://doi.org/10.1101/2022.10.03.510524" @default.
• W4302016073 hasPublicationYear "2022" @default.
• W4302016073 type Work @default.
• W4302016073 citedByCount "0" @default.
• W4302016073 crossrefType "posted-content" @default.
• W4302016073 hasAuthorship W4302016073A5025049560 @default.
• W4302016073 hasAuthorship W4302016073A5039166280 @default.
• W4302016073 hasAuthorship W4302016073A5046036187 @default.
• W4302016073 hasAuthorship W4302016073A5057114218 @default.
• W4302016073 hasAuthorship W4302016073A5063994483 @default.
• W4302016073 hasAuthorship W4302016073A5085865659 @default.
• W4302016073 hasAuthorship W4302016073A5089345616 @default.
• W4302016073 hasBestOaLocation W43020160731 @default.
• W4302016073 hasConcept C118552586 @default.
• W4302016073 hasConcept C126322002 @default.
• W4302016073 hasConcept C15744967 @default.
• W4302016073 hasConcept C169760540 @default.
• W4302016073 hasConcept C16993767 @default.
• W4302016073 hasConcept C2780352252 @default.
• W4302016073 hasConcept C2781118164 @default.
• W4302016073 hasConcept C50610925 @default.
• W4302016073 hasConcept C53927964 @default.
• W4302016073 hasConcept C55493867 @default.
• W4302016073 hasConcept C558461103 @default.
• W4302016073 hasConcept C70410870 @default.
• W4302016073 hasConcept C71315377 @default.
• W4302016073 hasConcept C71924100 @default.
• W4302016073 hasConcept C86803240 @default.
• W4302016073 hasConcept C90149880 @default.
• W4302016073 hasConcept C94412978 @default.
• W4302016073 hasConceptScore W4302016073C118552586 @default.
• W4302016073 hasConceptScore W4302016073C126322002 @default.
• W4302016073 hasConceptScore W4302016073C15744967 @default.
• W4302016073 hasConceptScore W4302016073C169760540 @default.
• W4302016073 hasConceptScore W4302016073C16993767 @default.
• W4302016073 hasConceptScore W4302016073C2780352252 @default.
• W4302016073 hasConceptScore W4302016073C2781118164 @default.
• W4302016073 hasConceptScore W4302016073C50610925 @default.
• W4302016073 hasConceptScore W4302016073C53927964 @default.
• W4302016073 hasConceptScore W4302016073C55493867 @default.
• W4302016073 hasConceptScore W4302016073C558461103 @default.
• W4302016073 hasConceptScore W4302016073C70410870 @default.
• W4302016073 hasConceptScore W4302016073C71315377 @default.
• W4302016073 hasConceptScore W4302016073C71924100 @default.
• W4302016073 hasConceptScore W4302016073C86803240 @default.
• W4302016073 hasConceptScore W4302016073C90149880 @default.
• W4302016073 hasConceptScore W4302016073C94412978 @default.
• W4302016073 hasLocation W43020160731 @default.

• next