Matches in SemOpenAlex for { <https://semopenalex.org/work/W4302024881> ?p ?o ?g. }
- W4302024881 endingPage "738901" @default.
- W4302024881 startingPage "738901" @default.
- W4302024881 abstract "As a specific ecological factor of the aquatic environment, salinity can significantly affect intestinal and intestinal microbial homeostasis, which play essential roles in maintaining host health and antibacterial function. To evaluate the effects of saline-alkali water on host health and immune response, in this study, the effects of hyperosmotic stress on intestinal functions, including the intestinal microecosystem, intestinal immune response-related gene expression and intestinal antioxidant capacity, were investigated in mandarin fish (Siniperca chuatsi) after 45 days of exposure to freshwater (0 ppt salinity) or 3 ppt salinity, 6 ppt salinity, 9 ppt salinity, and 12 ppt salinity water environments. The results revealed that the intestinal microbial community composition could be altered and reshaped by hyperosmotic stress. Notably, the relative abundances of the probiotic bacterium Lactobacillus, the pathogenic bacterium Vibrio, and the metabolism-related bacteria Cetobacterium and Gluconobacter in the 6 ppt salinity group was higher than those in other groups, whereas no significant difference was observed among five groups. The analysis of intestinal transcriptome revealed several differentially expressed genes (DEGs) associated with several immune-related DEGs related to proinflammatory cytokines, anti-inflammatory cytokines, antioxidant defense, antimicrobial effects, and cell apoptosis. According to an analysis of intestinal physiological properties, the activity of alkaline phosphatase (AKP) and acid phosphatase (ACP) was significantly increased by hyperosmotic stress, especially in the 6 ppt salinity group. The present study provides essential insights into the influences of saline-alkali water on the health status and immune functions of mandarin fish; additionally, it provides an important foundation for further studies on the effects of complex relationship between intestinal flora and complex host environment on host disease resistance." @default.
- W4302024881 created "2022-10-06" @default.
- W4302024881 creator A5008360970 @default.
- W4302024881 creator A5015480789 @default.
- W4302024881 creator A5016515478 @default.
- W4302024881 creator A5017560653 @default.
- W4302024881 creator A5049295617 @default.
- W4302024881 creator A5055174519 @default.
- W4302024881 creator A5055336898 @default.
- W4302024881 creator A5064222660 @default.
- W4302024881 creator A5070589892 @default.
- W4302024881 creator A5081151513 @default.
- W4302024881 creator A5081596270 @default.
- W4302024881 creator A5084135876 @default.
- W4302024881 creator A5084612503 @default.
- W4302024881 creator A5088275918 @default.
- W4302024881 date "2023-01-01" @default.
- W4302024881 modified "2023-10-11" @default.
- W4302024881 title "Effects of hyperosmotic stress on the intestinal microbiota, transcriptome, and immune function of mandarin fish (Siniperca chuatsi)" @default.
- W4302024881 cites W1489080036 @default.
- W4302024881 cites W163461100 @default.
- W4302024881 cites W1825711373 @default.
- W4302024881 cites W1912394394 @default.
- W4302024881 cites W1964525395 @default.
- W4302024881 cites W1980220254 @default.
- W4302024881 cites W1983135948 @default.
- W4302024881 cites W1988138080 @default.
- W4302024881 cites W1993065952 @default.
- W4302024881 cites W1999319284 @default.
- W4302024881 cites W1999373531 @default.
- W4302024881 cites W2016860528 @default.
- W4302024881 cites W2027327645 @default.
- W4302024881 cites W2042684813 @default.
- W4302024881 cites W2045106889 @default.
- W4302024881 cites W2056879548 @default.
- W4302024881 cites W2069347186 @default.
- W4302024881 cites W2085933321 @default.
- W4302024881 cites W2086155277 @default.
- W4302024881 cites W2088833470 @default.
- W4302024881 cites W2093921693 @default.
- W4302024881 cites W2104005232 @default.
- W4302024881 cites W2107277218 @default.
- W4302024881 cites W2108281900 @default.
- W4302024881 cites W2110082875 @default.
- W4302024881 cites W2113068948 @default.
- W4302024881 cites W2119908860 @default.
- W4302024881 cites W2126218947 @default.
- W4302024881 cites W2136879569 @default.
- W4302024881 cites W2137461479 @default.
- W4302024881 cites W2149515881 @default.
- W4302024881 cites W2156172166 @default.
- W4302024881 cites W2157107905 @default.
- W4302024881 cites W2161692005 @default.
- W4302024881 cites W2171192710 @default.
- W4302024881 cites W2172491396 @default.
- W4302024881 cites W2179438025 @default.
- W4302024881 cites W2206648169 @default.
- W4302024881 cites W2266478985 @default.
- W4302024881 cites W2287274698 @default.
- W4302024881 cites W2464957792 @default.
- W4302024881 cites W2588974261 @default.
- W4302024881 cites W2605570603 @default.
- W4302024881 cites W2770541357 @default.
- W4302024881 cites W2772557707 @default.
- W4302024881 cites W2783187108 @default.
- W4302024881 cites W2789702246 @default.
- W4302024881 cites W2799993875 @default.
- W4302024881 cites W2885216437 @default.
- W4302024881 cites W2889422945 @default.
- W4302024881 cites W2900697674 @default.
- W4302024881 cites W2903082388 @default.
- W4302024881 cites W2944604977 @default.
- W4302024881 cites W2951083569 @default.
- W4302024881 cites W2964238601 @default.
- W4302024881 cites W2982359845 @default.
- W4302024881 cites W2993057767 @default.
- W4302024881 cites W2999171863 @default.
- W4302024881 cites W3001093559 @default.
- W4302024881 cites W3023923910 @default.
- W4302024881 cites W3024004292 @default.
- W4302024881 cites W3025206462 @default.
- W4302024881 cites W3036748010 @default.
- W4302024881 cites W3040381078 @default.
- W4302024881 cites W3041682789 @default.
- W4302024881 cites W3042284215 @default.
- W4302024881 cites W3077133539 @default.
- W4302024881 cites W3080286089 @default.
- W4302024881 cites W3092815247 @default.
- W4302024881 cites W3110137129 @default.
- W4302024881 cites W3155171346 @default.
- W4302024881 cites W3157289078 @default.
- W4302024881 cites W3165423159 @default.
- W4302024881 cites W3166605453 @default.
- W4302024881 cites W3206737067 @default.
- W4302024881 cites W4206426469 @default.
- W4302024881 cites W4224318739 @default.
- W4302024881 doi "https://doi.org/10.1016/j.aquaculture.2022.738901" @default.
- W4302024881 hasPublicationYear "2023" @default.