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- W4302028126 endingPage "103221" @default.
- W4302028126 startingPage "103221" @default.
- W4302028126 abstract "Enhanced visuospatial abilities characterize the cognitive profile of a subgroup of autistics. However, the neural correlates underlying such cognitive strengths are largely unknown. Using functional magnetic resonance imaging (fMRI), we investigated the neural underpinnings of superior visuospatial functioning in different autistic subgroups. Twenty-seven autistic adults, including 13 with a Wechsler's Block Design peak (AUTp) and 14 without (AUTnp), and 23 typically developed adults (TYP) performed a classic mental rotation task. As expected, AUTp participants were faster at the task compared to TYP. At the neural level, AUTp participants showed enhanced bilateral parietal and occipital activation, stronger occipito-parietal and fronto-occipital connectivity, and diminished fronto-parietal connectivity compared to TYP. On the other hand, AUTnp participants presented greater activation in right and anterior regions compared to AUTp. In addition, reduced connectivity between occipital and parietal regions was observed in AUTnp compared to AUTp and TYP participants. A greater reliance on posterior regions is typically reported in the autism literature. Our results suggest that this commonly reported finding may be specific to a subgroup of autistic individuals with enhanced visuospatial functioning. Moreover, this study demonstrated that increased occipito-frontal synchronization was associated with superior visuospatial abilities in autism. This finding contradicts the long-range under-connectivity hypothesis in autism. Finally, given the relationship between distinct cognitive profiles in autism and our observed differences in brain functioning, future studies should provide an adequate characterization of the autistic subgroups in their research. The main limitations are small sample sizes and the inclusion of male-only participants." @default.
- W4302028126 created "2022-10-06" @default.
- W4302028126 creator A5017598141 @default.
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- W4302028126 creator A5077210721 @default.
- W4302028126 date "2022-01-01" @default.
- W4302028126 modified "2023-10-14" @default.
- W4302028126 title "Differential neural correlates underlying mental rotation processes in two distinct cognitive profiles in autism" @default.
- W4302028126 cites W1479903965 @default.
- W4302028126 cites W1568488526 @default.
- W4302028126 cites W1570145461 @default.
- W4302028126 cites W1570375135 @default.
- W4302028126 cites W1605955409 @default.
- W4302028126 cites W1936199890 @default.
- W4302028126 cites W1949996576 @default.
- W4302028126 cites W1963964586 @default.
- W4302028126 cites W1966614343 @default.
- W4302028126 cites W1966736941 @default.
- W4302028126 cites W1968466565 @default.
- W4302028126 cites W1969745577 @default.
- W4302028126 cites W1971896840 @default.
- W4302028126 cites W1973886162 @default.
- W4302028126 cites W1976036879 @default.
- W4302028126 cites W1980309199 @default.
- W4302028126 cites W1983183519 @default.
- W4302028126 cites W1992184506 @default.
- W4302028126 cites W1994016367 @default.
- W4302028126 cites W1999261641 @default.
- W4302028126 cites W2000697043 @default.
- W4302028126 cites W2018255931 @default.
- W4302028126 cites W2021289762 @default.
- W4302028126 cites W2021466515 @default.
- W4302028126 cites W2021971647 @default.
- W4302028126 cites W2024229438 @default.
- W4302028126 cites W2026452816 @default.
- W4302028126 cites W2028067702 @default.
- W4302028126 cites W2028313210 @default.
- W4302028126 cites W2030654102 @default.
- W4302028126 cites W2042981671 @default.
- W4302028126 cites W2044913036 @default.
- W4302028126 cites W2045960328 @default.
- W4302028126 cites W2046187238 @default.
- W4302028126 cites W2047485285 @default.
- W4302028126 cites W2048445568 @default.
- W4302028126 cites W2049723594 @default.
- W4302028126 cites W2050093397 @default.
- W4302028126 cites W2050729386 @default.
- W4302028126 cites W2051372586 @default.
- W4302028126 cites W2055103624 @default.
- W4302028126 cites W2055369770 @default.
- W4302028126 cites W2055866745 @default.
- W4302028126 cites W2057911790 @default.
- W4302028126 cites W2058289547 @default.
- W4302028126 cites W2061607227 @default.
- W4302028126 cites W2064364338 @default.
- W4302028126 cites W2065343501 @default.
- W4302028126 cites W2074895886 @default.
- W4302028126 cites W2078372031 @default.
- W4302028126 cites W2080016705 @default.
- W4302028126 cites W2082445603 @default.
- W4302028126 cites W2082863207 @default.
- W4302028126 cites W2084291081 @default.
- W4302028126 cites W2084384352 @default.
- W4302028126 cites W2085239809 @default.
- W4302028126 cites W2087505388 @default.
- W4302028126 cites W2092948036 @default.
- W4302028126 cites W2097072002 @default.
- W4302028126 cites W2102857950 @default.
- W4302028126 cites W2104198116 @default.
- W4302028126 cites W2104500862 @default.
- W4302028126 cites W2108468424 @default.
- W4302028126 cites W2109256935 @default.
- W4302028126 cites W2111613011 @default.
- W4302028126 cites W2112632726 @default.
- W4302028126 cites W2113293185 @default.
- W4302028126 cites W2113649077 @default.
- W4302028126 cites W2116442163 @default.
- W4302028126 cites W2119812349 @default.
- W4302028126 cites W2122623425 @default.
- W4302028126 cites W2124224090 @default.
- W4302028126 cites W2124249156 @default.
- W4302028126 cites W2127810520 @default.
- W4302028126 cites W2128359078 @default.
- W4302028126 cites W2131541104 @default.
- W4302028126 cites W2136022845 @default.
- W4302028126 cites W2137232302 @default.
- W4302028126 cites W2138723609 @default.
- W4302028126 cites W2139934183 @default.
- W4302028126 cites W2141020690 @default.
- W4302028126 cites W2142980009 @default.
- W4302028126 cites W2144446993 @default.
- W4302028126 cites W2144519701 @default.
- W4302028126 cites W2144773302 @default.
- W4302028126 cites W2146429584 @default.
- W4302028126 cites W2146437136 @default.
- W4302028126 cites W2146511652 @default.