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- W4302079082 abstract "Fifteen patients were studied 3 to 35 years after antrectomy, with a gastroduodenal (Billroth I (BI)) anastomosis in 8, and a gastrojejunal (Billroth II (BII)) anastomosis in 7. The investigations included gastric acid secretion, serum gastrin response to feeding and immunohistochemical search for gastrin‐producing cells in gastric remnant mucosal biopsies. All of the patients had hypochlorhydria. The gastrin response to feeding was minimal. Apart from a significantly higher value of serum gastrin 3 hours post‐prandial in BI operated as compared to BII operated patients, no greater differences were found in the gastrin production between the two groups of patients. No gastrin‐producing cells could be identified in the gastric remnant, not even in areas of pseudopyloric metaplasia. It is concluded that the gastrin production following antrectomy is caused by extragastric G‐cells; these cells are poorly stimulated by food, and do not respond to hypochlorhydria with hypergastrinaemia." @default.
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- W4302079082 date "1983-07-01" @default.
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- W4302079082 title "GASTRIN PRODUCTION FOLLOWING ANTRECTOMY" @default.
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- W4302079082 doi "https://doi.org/10.1111/j.1699-0463.1983.tb02741.x" @default.
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