FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4302299249> ?p ?o ?g. }

• W4302299249 abstract "Graft-derived cell-free DNA (GcfDNA) is a promising non-invasive biomarker for detecting allograft injury. In this study, we aimed to evaluate the efficacy of programmed monitoring of GcfDNA for identifying BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant recipients. We recruited 158 kidney transplant recipients between November 2020 and December 2021. Plasma GcfDNA was collected on the tenth day, first month, third month, and sixth month for programmed monitoring and one day before biopsy. ΔGcfDNA (cp/mL) was obtained by subtracting the baseline GcfDNA (cp/mL) from GcfDNA (cp/mL) of the latest programmed monitoring before biopsy. The receiver operating characteristic curve showed the diagnostic performance of GcfDNA (cp/mL) at biopsy time and an optimal area under the curve (AUC) of 0.68 in distinguishing pathologically proven BKPyVAN from pathologically unconfirmed BKPyVAN. In contrast, ΔGcfDNA (cp/mL) had a sensitivity and specificity of 80% and 84.6%, respectively, and an AUC of 0.83. When distinguishing clinically diagnosed BKPyVAN from clinical excluded BKPyVAN, the AUC of GcfDNA (cp/mL) was 0.59 at biopsy time, and ΔGcfDNA (cp/mL) had a sensitivity and specificity of 81.0% and 76.5%, respectively, and an AUC of 0.81. Plasma ΔGcfDNA (cp/mL) was not significantly different between TCMR [0.15 (0.08, 0.24) cp/mL] and pathologically proven BKPyVAN[0.34 (0.20, 0.49) cp/mL]. In conclusion, we recommend programmed monitoring of plasma GcfDNA levels after a kidney transplant. Based on our findings from the programmed monitoring, we have developed a novel algorithm that shows promising results in identifying and predicting BKPyVAN." @default.
• W4302299249 created "2022-10-06" @default.
• W4302299249 creator A5017397564 @default.
• W4302299249 creator A5026481037 @default.
• W4302299249 creator A5049001652 @default.
• W4302299249 creator A5051596488 @default.
• W4302299249 creator A5070478391 @default.
• W4302299249 date "2022-10-06" @default.
• W4302299249 modified "2023-09-26" @default.
• W4302299249 title "Detection of BK polyomavirus-associated nephropathy using plasma graft-derived cell-free DNA: Development of a novel algorithm from programmed monitoring" @default.
• W4302299249 cites W1788698477 @default.
• W4302299249 cites W2024692616 @default.
• W4302299249 cites W2103081012 @default.
• W4302299249 cites W2166628353 @default.
• W4302299249 cites W2171522478 @default.
• W4302299249 cites W2592945756 @default.
• W4302299249 cites W2608919594 @default.
• W4302299249 cites W2619138406 @default.
• W4302299249 cites W2768353035 @default.
• W4302299249 cites W2774126255 @default.
• W4302299249 cites W2807732072 @default.
• W4302299249 cites W2891123113 @default.
• W4302299249 cites W2896825908 @default.
• W4302299249 cites W2905905397 @default.
• W4302299249 cites W2913771669 @default.
• W4302299249 cites W2944291759 @default.
• W4302299249 cites W2945557230 @default.
• W4302299249 cites W3007842515 @default.
• W4302299249 cites W3023097846 @default.
• W4302299249 cites W3044959105 @default.
• W4302299249 cites W3050875799 @default.
• W4302299249 cites W3095592973 @default.
• W4302299249 cites W3135865843 @default.
• W4302299249 cites W3159506168 @default.
• W4302299249 cites W3182882553 @default.
• W4302299249 cites W4200346616 @default.
• W4302299249 cites W4225992543 @default.
• W4302299249 cites W4226340248 @default.
• W4302299249 cites W4281741410 @default.
• W4302299249 cites W4288050846 @default.
• W4302299249 doi "https://doi.org/10.3389/fimmu.2022.1006970" @default.
• W4302299249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36275762" @default.
• W4302299249 hasPublicationYear "2022" @default.
• W4302299249 type Work @default.
• W4302299249 citedByCount "0" @default.
• W4302299249 crossrefType "journal-article" @default.
• W4302299249 hasAuthorship W4302299249A5017397564 @default.
• W4302299249 hasAuthorship W4302299249A5026481037 @default.
• W4302299249 hasAuthorship W4302299249A5049001652 @default.
• W4302299249 hasAuthorship W4302299249A5051596488 @default.
• W4302299249 hasAuthorship W4302299249A5070478391 @default.
• W4302299249 hasBestOaLocation W43022992491 @default.
• W4302299249 hasConcept C11413529 @default.
• W4302299249 hasConcept C126322002 @default.
• W4302299249 hasConcept C126894567 @default.
• W4302299249 hasConcept C134018914 @default.
• W4302299249 hasConcept C152110520 @default.
• W4302299249 hasConcept C172680121 @default.
• W4302299249 hasConcept C2775934546 @default.
• W4302299249 hasConcept C2778258057 @default.
• W4302299249 hasConcept C2779234561 @default.
• W4302299249 hasConcept C2780091579 @default.
• W4302299249 hasConcept C2780303639 @default.
• W4302299249 hasConcept C2781087799 @default.
• W4302299249 hasConcept C2781184683 @default.
• W4302299249 hasConcept C2781197716 @default.
• W4302299249 hasConcept C41008148 @default.
• W4302299249 hasConcept C54355233 @default.
• W4302299249 hasConcept C55493867 @default.
• W4302299249 hasConcept C555293320 @default.
• W4302299249 hasConcept C58471807 @default.
• W4302299249 hasConcept C71924100 @default.
• W4302299249 hasConcept C76318530 @default.
• W4302299249 hasConcept C86803240 @default.
• W4302299249 hasConcept C90924648 @default.
• W4302299249 hasConceptScore W4302299249C11413529 @default.
• W4302299249 hasConceptScore W4302299249C126322002 @default.
• W4302299249 hasConceptScore W4302299249C126894567 @default.
• W4302299249 hasConceptScore W4302299249C134018914 @default.
• W4302299249 hasConceptScore W4302299249C152110520 @default.
• W4302299249 hasConceptScore W4302299249C172680121 @default.
• W4302299249 hasConceptScore W4302299249C2775934546 @default.
• W4302299249 hasConceptScore W4302299249C2778258057 @default.
• W4302299249 hasConceptScore W4302299249C2779234561 @default.
• W4302299249 hasConceptScore W4302299249C2780091579 @default.
• W4302299249 hasConceptScore W4302299249C2780303639 @default.
• W4302299249 hasConceptScore W4302299249C2781087799 @default.
• W4302299249 hasConceptScore W4302299249C2781184683 @default.
• W4302299249 hasConceptScore W4302299249C2781197716 @default.
• W4302299249 hasConceptScore W4302299249C41008148 @default.
• W4302299249 hasConceptScore W4302299249C54355233 @default.
• W4302299249 hasConceptScore W4302299249C55493867 @default.
• W4302299249 hasConceptScore W4302299249C555293320 @default.
• W4302299249 hasConceptScore W4302299249C58471807 @default.
• W4302299249 hasConceptScore W4302299249C71924100 @default.
• W4302299249 hasConceptScore W4302299249C76318530 @default.
• W4302299249 hasConceptScore W4302299249C86803240 @default.
• W4302299249 hasConceptScore W4302299249C90924648 @default.
• W4302299249 hasFunder F4320322922 @default.
• W4302299249 hasLocation W43022992491 @default.

• next