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- W4302387898 abstract "The new Food and Drug Administration (FDA) guidelines for evaluating contraceptives are blamed by some researchers for killing the initiative of a few drug firms undertaking long-term contraceptive research and development. Only government-sponsored work will follow. Required animal studies are causing the cost of contraceptive research and development to go up. Also more than 8 years would be required for introduction of a new agent to the public. The FDA is not considered by some researchers to be competent to monitor safety and effectiveness due to political, journalistic, and legislative pressures and lack of competent people to handle applications. More available government funds and private foundation funds are needed to further research. Widespread use of oral contraceptives makes evaluation for mutagenic effects imperative. Several assay methods are proposed. More studied related to delayed carcinogenic effects and to fill specific gaps in knowledge about oral contraceptives are also needed. Another researcher recommended use of less effective alternative methods of contraception with surgical interruption of unwanted pregnancies. At the beginning of oral contraceptive approval, pressures caused an irration approach to controlled studies; a more rational approach has been followed in recent years." @default.
- W4302387898 created "2022-10-06" @default.
- W4302387898 date "1970-01-21" @default.
- W4302387898 modified "2023-09-29" @default.
- W4302387898 title "Manufacturers cut promising contraceptive research, saying FDA regulations requiring animal toxicity studies are too time-consuming, expensive." @default.
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