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- W4302408175 abstract "(1) In clinical trials of topical tacrolimus (an immunosuppressant), transient skin irritation, usually at the site of application, occurred in about 0.5% to 1.3% of adult patients who had also ingested ethyl alcohol. This adverse effect has also been observed with topical pimecrolimus, a related drug. (2) Three paediatric cases have also been published. The alcohol they ingested was one of the excipients of an oral drug. (3) If skin irritation occurs at the application site for topical tacrolimus, the role of ethyl alcohol, which may have been used as an excipient for a co-administered oral drug, should be borne in mind." @default.
- W4302408175 created "2022-10-06" @default.
- W4302408175 date "2007-12-01" @default.
- W4302408175 modified "2023-10-18" @default.
- W4302408175 title "Topical tacrolimus plus oral alcohol: skin irritation." @default.
- W4302408175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18092421" @default.
- W4302408175 hasPublicationYear "2007" @default.
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