Matches in SemOpenAlex for { <https://semopenalex.org/work/W4302469328> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4302469328 endingPage "926" @default.
- W4302469328 startingPage "924" @default.
- W4302469328 abstract "A 17-year-old white adolescent had a history of chronic diarrhea, delayed puberty, and growth failure. Investigations excluded cystic fibrosis, Shwachman syndrome, and endocrine causes of growth failure. Severe steatorrhea was diagnosed from fecal fat studies, and a jejunal suction biopsy showed total villus atrophy, consistent with a diagnosis of celiac disease. Following introduction of a gluten-free diet, his appetite and growth improved, but he continued to have abdominal discomfort and loose offensive bowel motions. One year later, severe steatorrhea was present. A repeat jejunal biopsy showed partial recovery of villus architecture. Serum immunoreactive trypsinogen level was low, which was highly suggestive of exocrine pancreatic failure. Results of quantitative pancreatic stimulation test confirmed the presence of primary pancreatic insufficiency. After introduction of oral pancreatic enzyme supplements with meals, his gastrointestinal symptoms resolved and growth velocity accelerated. Previously, primary pancreatic insufficiency has only been described in elderly patients with long-standing untreated celiac disease. This case, however, emphasizes that pancreatic failure can occur with celiac disease at any age. Determination of a serum immunoreactive trypsinogen level should be considered a useful screening tool for pancreatic insufficiency in patients with celiac disease who have not responded to a gluten-free diet." @default.
- W4302469328 created "2022-10-06" @default.
- W4302469328 creator A5026258529 @default.
- W4302469328 creator A5031493480 @default.
- W4302469328 creator A5044718593 @default.
- W4302469328 creator A5050539641 @default.
- W4302469328 creator A5070196429 @default.
- W4302469328 date "1987-12-01" @default.
- W4302469328 modified "2023-09-26" @default.
- W4302469328 title "Treatment Failure in Celiac Disease Due to Coexistent Exocrine Pancreatic Insufficiency" @default.
- W4302469328 doi "https://doi.org/10.1542/peds.80.6.924" @default.
- W4302469328 hasPublicationYear "1987" @default.
- W4302469328 type Work @default.
- W4302469328 citedByCount "10" @default.
- W4302469328 countsByYear W43024693282015 @default.
- W4302469328 countsByYear W43024693282016 @default.
- W4302469328 countsByYear W43024693282022 @default.
- W4302469328 crossrefType "journal-article" @default.
- W4302469328 hasAuthorship W4302469328A5026258529 @default.
- W4302469328 hasAuthorship W4302469328A5031493480 @default.
- W4302469328 hasAuthorship W4302469328A5044718593 @default.
- W4302469328 hasAuthorship W4302469328A5050539641 @default.
- W4302469328 hasAuthorship W4302469328A5070196429 @default.
- W4302469328 hasConcept C126322002 @default.
- W4302469328 hasConcept C181199279 @default.
- W4302469328 hasConcept C185592680 @default.
- W4302469328 hasConcept C2775934546 @default.
- W4302469328 hasConcept C2775967933 @default.
- W4302469328 hasConcept C2776737053 @default.
- W4302469328 hasConcept C2776938444 @default.
- W4302469328 hasConcept C2777152358 @default.
- W4302469328 hasConcept C2777675875 @default.
- W4302469328 hasConcept C2778764654 @default.
- W4302469328 hasConcept C2780340462 @default.
- W4302469328 hasConcept C2781286802 @default.
- W4302469328 hasConcept C55493867 @default.
- W4302469328 hasConcept C71924100 @default.
- W4302469328 hasConcept C90924648 @default.
- W4302469328 hasConceptScore W4302469328C126322002 @default.
- W4302469328 hasConceptScore W4302469328C181199279 @default.
- W4302469328 hasConceptScore W4302469328C185592680 @default.
- W4302469328 hasConceptScore W4302469328C2775934546 @default.
- W4302469328 hasConceptScore W4302469328C2775967933 @default.
- W4302469328 hasConceptScore W4302469328C2776737053 @default.
- W4302469328 hasConceptScore W4302469328C2776938444 @default.
- W4302469328 hasConceptScore W4302469328C2777152358 @default.
- W4302469328 hasConceptScore W4302469328C2777675875 @default.
- W4302469328 hasConceptScore W4302469328C2778764654 @default.
- W4302469328 hasConceptScore W4302469328C2780340462 @default.
- W4302469328 hasConceptScore W4302469328C2781286802 @default.
- W4302469328 hasConceptScore W4302469328C55493867 @default.
- W4302469328 hasConceptScore W4302469328C71924100 @default.
- W4302469328 hasConceptScore W4302469328C90924648 @default.
- W4302469328 hasIssue "6" @default.
- W4302469328 hasLocation W43024693281 @default.
- W4302469328 hasOpenAccess W4302469328 @default.
- W4302469328 hasPrimaryLocation W43024693281 @default.
- W4302469328 hasRelatedWork W1922479390 @default.
- W4302469328 hasRelatedWork W2004419097 @default.
- W4302469328 hasRelatedWork W2008687525 @default.
- W4302469328 hasRelatedWork W2009041699 @default.
- W4302469328 hasRelatedWork W2058832876 @default.
- W4302469328 hasRelatedWork W2400748808 @default.
- W4302469328 hasRelatedWork W2418517148 @default.
- W4302469328 hasRelatedWork W2487458214 @default.
- W4302469328 hasRelatedWork W3006823261 @default.
- W4302469328 hasRelatedWork W67401187 @default.
- W4302469328 hasVolume "80" @default.
- W4302469328 isParatext "false" @default.
- W4302469328 isRetracted "false" @default.
- W4302469328 workType "article" @default.