FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4302763248> ?p ?o ?g. }

• W4302763248 endingPage "295" @default.
• W4302763248 startingPage "281" @default.
• W4302763248 abstract "In this paper, we reported the synthesis of a novel series of (2-hydroxyphenyl)-5-phenyl-6-(pyrrolidine-1-carbonyl)-1H-pyrano[2,3-d]pyrimidine-2,4(3H,5H)-dione derivatives 5(a-j) by the reaction of 4-hydroxy coumarin, substituted aldehydes, barbituric acid, and pyrolidine in ethanol at ambient temperature. The titled pyranopyrimidines 5(a-j) were characterized by spectral analysis including IR, NMR (1H & 13C), and HRMS. The newly synthesized compounds were examined for in vitro anti-inflammatory activity. The results demonstrated that compound 5b displayed excellent efficacy and the remaining compounds exhibited moderate activity. Also, the potency of the new compounds toward antimicrobial and antifungal activity was investigated by a disk diffusion method. The results show that compounds 5b and 5g were more potent than the other compounds. Furthermore, the molecular docking studies were carried out using a COX-2 receptor." @default.
• W4302763248 created "2022-10-07" @default.
• W4302763248 creator A5000556010 @default.
• W4302763248 creator A5012446647 @default.
• W4302763248 creator A5051563187 @default.
• W4302763248 creator A5076965508 @default.
• W4302763248 date "2022-10-06" @default.
• W4302763248 modified "2023-09-27" @default.
• W4302763248 title "An efficient one pot synthesis of (2-hydroxyphenyl)-5-phenyl-6-(pyrrolidine-1-carbonyl)-1H-pyrano[2,3-d]pyrimidine-2,4(3H,5H)-dione derivatives as a potent biological agents" @default.
• W4302763248 cites W2101817087 @default.
• W4302763248 cites W2128525919 @default.
• W4302763248 cites W2251534193 @default.
• W4302763248 cites W2581282767 @default.
• W4302763248 cites W2588695084 @default.
• W4302763248 cites W2626802955 @default.
• W4302763248 cites W2726389825 @default.
• W4302763248 cites W2808255165 @default.
• W4302763248 cites W2896692972 @default.
• W4302763248 cites W2905409625 @default.
• W4302763248 cites W2914377858 @default.
• W4302763248 cites W2938415285 @default.
• W4302763248 cites W2957504299 @default.
• W4302763248 cites W2972597060 @default.
• W4302763248 cites W2982297806 @default.
• W4302763248 cites W2994612910 @default.
• W4302763248 cites W2997494869 @default.
• W4302763248 cites W2997631020 @default.
• W4302763248 cites W3012206459 @default.
• W4302763248 cites W3012211606 @default.
• W4302763248 cites W3042872976 @default.
• W4302763248 cites W3090934236 @default.
• W4302763248 cites W3102243945 @default.
• W4302763248 cites W3107373272 @default.
• W4302763248 cites W3108919845 @default.
• W4302763248 doi "https://doi.org/10.1080/15257770.2022.2127765" @default.
• W4302763248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36200641" @default.
• W4302763248 hasPublicationYear "2022" @default.
• W4302763248 type Work @default.
• W4302763248 citedByCount "0" @default.
• W4302763248 crossrefType "journal-article" @default.
• W4302763248 hasAuthorship W4302763248A5000556010 @default.
• W4302763248 hasAuthorship W4302763248A5012446647 @default.
• W4302763248 hasAuthorship W4302763248A5051563187 @default.
• W4302763248 hasAuthorship W4302763248A5076965508 @default.
• W4302763248 hasConcept C103319777 @default.
• W4302763248 hasConcept C116073593 @default.
• W4302763248 hasConcept C118939319 @default.
• W4302763248 hasConcept C16005928 @default.
• W4302763248 hasConcept C161790260 @default.
• W4302763248 hasConcept C163111631 @default.
• W4302763248 hasConcept C178790620 @default.
• W4302763248 hasConcept C185592680 @default.
• W4302763248 hasConcept C202751555 @default.
• W4302763248 hasConcept C21951064 @default.
• W4302763248 hasConcept C2778851528 @default.
• W4302763248 hasConcept C2779321679 @default.
• W4302763248 hasConcept C2779548794 @default.
• W4302763248 hasConcept C2779793070 @default.
• W4302763248 hasConcept C2780161600 @default.
• W4302763248 hasConcept C2781338262 @default.
• W4302763248 hasConcept C4937899 @default.
• W4302763248 hasConcept C55493867 @default.
• W4302763248 hasConcept C71240020 @default.
• W4302763248 hasConcept C71924100 @default.
• W4302763248 hasConceptScore W4302763248C103319777 @default.
• W4302763248 hasConceptScore W4302763248C116073593 @default.
• W4302763248 hasConceptScore W4302763248C118939319 @default.
• W4302763248 hasConceptScore W4302763248C16005928 @default.
• W4302763248 hasConceptScore W4302763248C161790260 @default.
• W4302763248 hasConceptScore W4302763248C163111631 @default.
• W4302763248 hasConceptScore W4302763248C178790620 @default.
• W4302763248 hasConceptScore W4302763248C185592680 @default.
• W4302763248 hasConceptScore W4302763248C202751555 @default.
• W4302763248 hasConceptScore W4302763248C21951064 @default.
• W4302763248 hasConceptScore W4302763248C2778851528 @default.
• W4302763248 hasConceptScore W4302763248C2779321679 @default.
• W4302763248 hasConceptScore W4302763248C2779548794 @default.
• W4302763248 hasConceptScore W4302763248C2779793070 @default.
• W4302763248 hasConceptScore W4302763248C2780161600 @default.
• W4302763248 hasConceptScore W4302763248C2781338262 @default.
• W4302763248 hasConceptScore W4302763248C4937899 @default.
• W4302763248 hasConceptScore W4302763248C55493867 @default.
• W4302763248 hasConceptScore W4302763248C71240020 @default.
• W4302763248 hasConceptScore W4302763248C71924100 @default.
• W4302763248 hasIssue "4" @default.
• W4302763248 hasLocation W43027632481 @default.
• W4302763248 hasLocation W43027632482 @default.
• W4302763248 hasOpenAccess W4302763248 @default.
• W4302763248 hasPrimaryLocation W43027632481 @default.
• W4302763248 hasRelatedWork W2011065158 @default.
• W4302763248 hasRelatedWork W2053427352 @default.
• W4302763248 hasRelatedWork W2055105849 @default.
• W4302763248 hasRelatedWork W2121453280 @default.
• W4302763248 hasRelatedWork W2177681712 @default.
• W4302763248 hasRelatedWork W2898643119 @default.
• W4302763248 hasRelatedWork W3039337373 @default.
• W4302763248 hasRelatedWork W4214577294 @default.
• W4302763248 hasRelatedWork W4302763248 @default.

• next