Matches in SemOpenAlex for { <https://semopenalex.org/work/W4303684896> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W4303684896 abstract "The present study aimed to determine whether current commercial immunoassays are adequate for detecting anti-Omicron antibodies. We analyzed the anti-SARS-CoV-2 antibody response of 23 unvaccinated individuals 1-2 months after an Omicron infection. All blood samples were tested with a live virus neutralization assay using a clinical Omicron BA.1 strain and four commercial SARS-CoV-2 immunoassays. We assessed three anti-Spike immunoassays (SARS-CoV-2 IgG II Quant [Abbott S], Wantaï anti-SARS-CoV-2 antibody ELISA [Wantaï], Elecsys Anti-SARS-CoV-2 S assay [Roche]) and one anti-Nucleocapsid immunoassay (Abbott SARS-CoV-2 IgG assay [Abbott N]). Omicron neutralizing antibodies were detected in all samples with the live virus neutralization assay. The detection rate of the Abbott S, Wantai, Roche, and Abbott N immunoassays were 65.2%, 69.6%, 86.9%, and 91.3%, respectively. The sensitivities of Abbott S and Wantai immunoassays were significantly lower than that of the live virus neutralization assay (p = 0.004, p = 0.009; Fisher's exact test). Antibody concentrations obtained with anti-S immunoassays were correlated with Omicron neutralizing antibody concentrations. These data provide clinical evidence of the loss of performance of some commercial immunoassays to detect antibodies elicited by Omicron infections. It highlights the need to optimize these assays by adapting antigens to the circulating SARS-CoV-2 strains." @default.
- W4303684896 created "2022-10-09" @default.
- W4303684896 creator A5000614492 @default.
- W4303684896 creator A5002155014 @default.
- W4303684896 creator A5010807056 @default.
- W4303684896 creator A5018744066 @default.
- W4303684896 creator A5042225568 @default.
- W4303684896 creator A5043771285 @default.
- W4303684896 creator A5058002123 @default.
- W4303684896 creator A5068125354 @default.
- W4303684896 creator A5073159605 @default.
- W4303684896 creator A5080763997 @default.
- W4303684896 creator A5082030928 @default.
- W4303684896 date "2022-10-17" @default.
- W4303684896 modified "2023-10-18" @default.
- W4303684896 title "Current immunoassays and detection of antibodies elicited by Omicron SARS‐CoV‐2 infection" @default.
- W4303684896 cites W3013985547 @default.
- W4303684896 cites W3083878398 @default.
- W4303684896 cites W3089492121 @default.
- W4303684896 cites W3194955934 @default.
- W4303684896 cites W3196867016 @default.
- W4303684896 cites W3198207072 @default.
- W4303684896 cites W3204643611 @default.
- W4303684896 cites W3215672128 @default.
- W4303684896 cites W4200217754 @default.
- W4303684896 cites W4205360481 @default.
- W4303684896 cites W4214531829 @default.
- W4303684896 cites W4220830840 @default.
- W4303684896 cites W4220977983 @default.
- W4303684896 cites W4223541187 @default.
- W4303684896 cites W4284677486 @default.
- W4303684896 cites W4284881870 @default.
- W4303684896 cites W4303684896 @default.
- W4303684896 doi "https://doi.org/10.1002/jmv.28200" @default.
- W4303684896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36207814" @default.
- W4303684896 hasPublicationYear "2022" @default.
- W4303684896 type Work @default.
- W4303684896 citedByCount "8" @default.
- W4303684896 countsByYear W43036848962022 @default.
- W4303684896 countsByYear W43036848962023 @default.
- W4303684896 crossrefType "journal-article" @default.
- W4303684896 hasAuthorship W4303684896A5000614492 @default.
- W4303684896 hasAuthorship W4303684896A5002155014 @default.
- W4303684896 hasAuthorship W4303684896A5010807056 @default.
- W4303684896 hasAuthorship W4303684896A5018744066 @default.
- W4303684896 hasAuthorship W4303684896A5042225568 @default.
- W4303684896 hasAuthorship W4303684896A5043771285 @default.
- W4303684896 hasAuthorship W4303684896A5058002123 @default.
- W4303684896 hasAuthorship W4303684896A5068125354 @default.
- W4303684896 hasAuthorship W4303684896A5073159605 @default.
- W4303684896 hasAuthorship W4303684896A5080763997 @default.
- W4303684896 hasAuthorship W4303684896A5082030928 @default.
- W4303684896 hasBestOaLocation W43036848962 @default.
- W4303684896 hasConcept C14086860 @default.
- W4303684896 hasConcept C142724271 @default.
- W4303684896 hasConcept C159047783 @default.
- W4303684896 hasConcept C159654299 @default.
- W4303684896 hasConcept C203014093 @default.
- W4303684896 hasConcept C2522874641 @default.
- W4303684896 hasConcept C2779134260 @default.
- W4303684896 hasConcept C2779261636 @default.
- W4303684896 hasConcept C2780420688 @default.
- W4303684896 hasConcept C3007834351 @default.
- W4303684896 hasConcept C3008058167 @default.
- W4303684896 hasConcept C524204448 @default.
- W4303684896 hasConcept C71924100 @default.
- W4303684896 hasConceptScore W4303684896C14086860 @default.
- W4303684896 hasConceptScore W4303684896C142724271 @default.
- W4303684896 hasConceptScore W4303684896C159047783 @default.
- W4303684896 hasConceptScore W4303684896C159654299 @default.
- W4303684896 hasConceptScore W4303684896C203014093 @default.
- W4303684896 hasConceptScore W4303684896C2522874641 @default.
- W4303684896 hasConceptScore W4303684896C2779134260 @default.
- W4303684896 hasConceptScore W4303684896C2779261636 @default.
- W4303684896 hasConceptScore W4303684896C2780420688 @default.
- W4303684896 hasConceptScore W4303684896C3007834351 @default.
- W4303684896 hasConceptScore W4303684896C3008058167 @default.
- W4303684896 hasConceptScore W4303684896C524204448 @default.
- W4303684896 hasConceptScore W4303684896C71924100 @default.
- W4303684896 hasIssue "1" @default.
- W4303684896 hasLocation W43036848961 @default.
- W4303684896 hasLocation W43036848962 @default.
- W4303684896 hasLocation W43036848963 @default.
- W4303684896 hasOpenAccess W4303684896 @default.
- W4303684896 hasPrimaryLocation W43036848961 @default.
- W4303684896 hasRelatedWork W1545923077 @default.
- W4303684896 hasRelatedWork W2063036651 @default.
- W4303684896 hasRelatedWork W2093961711 @default.
- W4303684896 hasRelatedWork W2309520848 @default.
- W4303684896 hasRelatedWork W3040004795 @default.
- W4303684896 hasRelatedWork W3110499570 @default.
- W4303684896 hasRelatedWork W3114250596 @default.
- W4303684896 hasRelatedWork W3133547117 @default.
- W4303684896 hasRelatedWork W4311961882 @default.
- W4303684896 hasRelatedWork W4385622522 @default.
- W4303684896 hasVolume "95" @default.
- W4303684896 isParatext "false" @default.
- W4303684896 isRetracted "false" @default.
- W4303684896 workType "article" @default.