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• W4303959069 abstract "An effective method for separating and purifying critical saponins (polyphyllin II and polyphyllin VII) from a Paris polyphylla var. yunnanensis extract was developed in this study which was environmentally friendly and economical. Static adsorption kinetics, thermodynamics, and the dynamic adsorption-desorption of macroporous resins were investigated, and then the conditions of purification and separation were optimized by fitting with an adsorption thermodynamics equation and a kinetic equation. Effective NKA-9 resin from seven macroporous resins was screened out to separate and purify the two saponins. The static adsorption and dynamic adsorption were chemical and physical adsorption dual-processes on the NKA-9 resin. Under the optimum parameters, the contents of polyphyllin II and polyphyllin VII in the product were 17.3-fold and 28.6-fold those in plant extracts, respectively. The total yields of the two saponins were 93.16%. This research thus provides a theoretical foundation for the large-scale industrial production of the natural drugs polyphyllin II and polyphyllin VII." @default.
• W4303959069 created "2022-10-10" @default.
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• W4303959069 date "2022-10-06" @default.
• W4303959069 modified "2023-10-16" @default.
• W4303959069 title "Separation and Purification of Two Saponins from Paris polyphylla var. yunnanensis by a Macroporous Resin" @default.
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• W4303959069 doi "https://doi.org/10.3390/molecules27196626" @default.
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• W4303959069 hasPublicationYear "2022" @default.
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