FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304114401> ?p ?o ?g. }

• W4304114401 endingPage "1692" @default.
• W4304114401 startingPage "1685" @default.
• W4304114401 abstract "Background: It is important to document the performance of rapid antigen tests (Ag-RDTs) in detecting SARS-CoV-2 variants. Objective: To compare the performance of Ag-RDTs in detecting the Delta (B.1.617.2) and Omicron (B.1.1.529) variants of SARS-CoV-2. Design: Secondary analysis of a prospective cohort study that enrolled participants between 18 October 2021 and 24 January 2022. Participants did Ag-RDTs and collected samples for reverse transcriptase polymerase chain reaction (RT-PCR) testing every 48 hours for 15 days. Setting: The parent study enrolled participants throughout the mainland United States through a digital platform. All participants self-collected anterior nasal swabs for rapid antigen testing and RT-PCR testing. All Ag-RDTs were completed at home, whereas nasal swabs for RT-PCR were shipped to a central laboratory. Participants: Of 7349 participants enrolled in the parent study, 5779 asymptomatic persons who tested negative for SARS-CoV-2 on day 1 of the study were eligible for this substudy. Measurements: Sensitivity of Ag-RDTs on the same day as the first positive (index) RT-PCR result and 48 hours after the first positive RT-PCR result. Results: A total of 207 participants were positive on RT-PCR (58 Delta, 149 Omicron). Differences in sensitivity between variants were not statistically significant (same day: Delta, 15.5% [95% CI, 6.2% to 24.8%] vs. Omicron, 22.1% [CI, 15.5% to 28.8%]; at 48 hours: Delta, 44.8% [CI, 32.0% to 57.6%] vs. Omicron, 49.7% [CI, 41.6% to 57.6%]). Among 109 participants who had RT-PCR–positive results for 48 hours, rapid antigen sensitivity did not differ significantly between Delta- and Omicron-infected participants (48-hour sensitivity: Delta, 81.5% [CI, 66.8% to 96.1%] vs. Omicron, 78.0% [CI, 69.1% to 87.0%]). Only 7.2% of the 69 participants with RT-PCR–positive results for shorter than 48 hours tested positive by Ag-RDT within 1 week; those with Delta infections remained consistently negative on Ag-RDTs. Limitation: A testing frequency of 48 hours does not allow a finer temporal resolution of the analysis of test performance, and the results of Ag-RDTs are based on self-report. Conclusion: The performance of Ag-RDTs in persons infected with the SARS-CoV-2 Omicron variant is not inferior to that in persons with Delta infections. Serial testing improved the sensitivity of Ag-RDTs for both variants. The performance of rapid antigen testing varies on the basis of duration of RT-PCR positivity. Primary Funding Source: National Heart, Lung, and Blood Institute of the National Institutes of Health." @default.
• W4304114401 created "2022-10-11" @default.
• W4304114401 creator A5002199836 @default.
• W4304114401 creator A5003631214 @default.
• W4304114401 creator A5006791475 @default.
• W4304114401 creator A5008107426 @default.
• W4304114401 creator A5008975117 @default.
• W4304114401 creator A5011685760 @default.
• W4304114401 creator A5017527636 @default.
• W4304114401 creator A5017773903 @default.
• W4304114401 creator A5027695598 @default.
• W4304114401 creator A5038400602 @default.
• W4304114401 creator A5039539954 @default.
• W4304114401 creator A5041036157 @default.
• W4304114401 creator A5044183597 @default.
• W4304114401 creator A5044326070 @default.
• W4304114401 creator A5047959863 @default.
• W4304114401 creator A5050411008 @default.
• W4304114401 creator A5052539701 @default.
• W4304114401 creator A5059167713 @default.
• W4304114401 creator A5071497421 @default.
• W4304114401 creator A5071629254 @default.
• W4304114401 creator A5071695607 @default.
• W4304114401 creator A5072324131 @default.
• W4304114401 creator A5073492625 @default.
• W4304114401 creator A5074292303 @default.
• W4304114401 creator A5077905008 @default.
• W4304114401 creator A5078716241 @default.
• W4304114401 creator A5080710145 @default.
• W4304114401 creator A5081943007 @default.
• W4304114401 creator A5082960906 @default.
• W4304114401 creator A5083581553 @default.
• W4304114401 creator A5089836483 @default.
• W4304114401 creator A5091056312 @default.
• W4304114401 creator A5091064969 @default.
• W4304114401 creator A5074857481 @default.
• W4304114401 date "2022-12-01" @default.
• W4304114401 modified "2023-10-02" @default.
• W4304114401 title "Comparison of Rapid Antigen Tests' Performance Between Delta and Omicron Variants of SARS-CoV-2" @default.
• W4304114401 cites W2508631962 @default.
• W4304114401 cites W2804869870 @default.
• W4304114401 cites W2975208726 @default.
• W4304114401 cites W3044073716 @default.
• W4304114401 cites W3090433892 @default.
• W4304114401 cites W3102538147 @default.
• W4304114401 cites W3160887443 @default.
• W4304114401 cites W3173352863 @default.
• W4304114401 cites W4200012588 @default.
• W4304114401 cites W4200307336 @default.
• W4304114401 cites W4200328944 @default.
• W4304114401 cites W4200373972 @default.
• W4304114401 cites W4205754095 @default.
• W4304114401 cites W4206233467 @default.
• W4304114401 cites W4206356412 @default.
• W4304114401 cites W4206644256 @default.
• W4304114401 cites W4210788395 @default.
• W4304114401 cites W4210889272 @default.
• W4304114401 cites W4212918168 @default.
• W4304114401 cites W4290039435 @default.
• W4304114401 cites W4290087601 @default.
• W4304114401 doi "https://doi.org/10.7326/m22-0760" @default.
• W4304114401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36215709" @default.
• W4304114401 hasPublicationYear "2022" @default.
• W4304114401 type Work @default.
• W4304114401 citedByCount "21" @default.
• W4304114401 countsByYear W43041144012022 @default.
• W4304114401 countsByYear W43041144012023 @default.
• W4304114401 crossrefType "journal-article" @default.
• W4304114401 hasAuthorship W4304114401A5002199836 @default.
• W4304114401 hasAuthorship W4304114401A5003631214 @default.
• W4304114401 hasAuthorship W4304114401A5006791475 @default.
• W4304114401 hasAuthorship W4304114401A5008107426 @default.
• W4304114401 hasAuthorship W4304114401A5008975117 @default.
• W4304114401 hasAuthorship W4304114401A5011685760 @default.
• W4304114401 hasAuthorship W4304114401A5017527636 @default.
• W4304114401 hasAuthorship W4304114401A5017773903 @default.
• W4304114401 hasAuthorship W4304114401A5027695598 @default.
• W4304114401 hasAuthorship W4304114401A5038400602 @default.
• W4304114401 hasAuthorship W4304114401A5039539954 @default.
• W4304114401 hasAuthorship W4304114401A5041036157 @default.
• W4304114401 hasAuthorship W4304114401A5044183597 @default.
• W4304114401 hasAuthorship W4304114401A5044326070 @default.
• W4304114401 hasAuthorship W4304114401A5047959863 @default.
• W4304114401 hasAuthorship W4304114401A5050411008 @default.
• W4304114401 hasAuthorship W4304114401A5052539701 @default.
• W4304114401 hasAuthorship W4304114401A5059167713 @default.
• W4304114401 hasAuthorship W4304114401A5071497421 @default.
• W4304114401 hasAuthorship W4304114401A5071629254 @default.
• W4304114401 hasAuthorship W4304114401A5071695607 @default.
• W4304114401 hasAuthorship W4304114401A5072324131 @default.
• W4304114401 hasAuthorship W4304114401A5073492625 @default.
• W4304114401 hasAuthorship W4304114401A5074292303 @default.
• W4304114401 hasAuthorship W4304114401A5074857481 @default.
• W4304114401 hasAuthorship W4304114401A5077905008 @default.
• W4304114401 hasAuthorship W4304114401A5078716241 @default.
• W4304114401 hasAuthorship W4304114401A5080710145 @default.
• W4304114401 hasAuthorship W4304114401A5081943007 @default.
• W4304114401 hasAuthorship W4304114401A5082960906 @default.

• next