FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304136060> ?p ?o ?g. }

• W4304136060 endingPage "7" @default.
• W4304136060 startingPage "1" @default.
• W4304136060 abstract "To date, few studies have investigated the toxicological effects of the combined use of amphetamine and heroin in the heart. Hence, the aim of this study was to identify indicators for clinical evaluation and prevention of cardiac injury induced by the combined use of amphetamine and heroin. Four different groups were analyzed: (1) normal group (n＝25；average age＝35 ± 6.8); (2) heart disease group (n＝25；average age＝58 ± 17.2); (3) drug abusers (n = 27; average age = 37 ± 7.7); (4) drug abstainers (previous amphetamine-heroin users who had been drug-free for more than two weeks; n = 22; average age = 35 ± 5.6). The activity of MMPs, and levels of TNF-α, IL-6, GH, IGF-I, and several serum biomarkers were examined to evaluate the impact of drug abuse on the heart. The selected plasma biomarkers and classic cardiac biomarkers were significantly increased compared to the normal group. The zymography data showed the changes in cardiac-remodeling enzymes MMP-9 and MMP-2 among combined users of amphetamine and heroin. The levels of TNF-α and IL-6 only increased in the heart disease group. Growth hormone was increased; however, IGF-I level decreased with drug abuse and the level was not restored by abstinence. We speculated that the amphetamine-heroin users might pose risk to initiate heart disease even though the users abstained for more than two weeks. The activity change of MMP-9 and MMP-2 can be a direct reason affecting heart function. The indirect reason may be related to liver damage by drug abuse reduce IGF-1 production to protect heart function." @default.
• W4304136060 created "2022-10-11" @default.
• W4304136060 creator A5017165971 @default.
• W4304136060 creator A5024637369 @default.
• W4304136060 creator A5025462564 @default.
• W4304136060 creator A5025617602 @default.
• W4304136060 creator A5046155407 @default.
• W4304136060 creator A5046900257 @default.
• W4304136060 creator A5053360201 @default.
• W4304136060 creator A5062745561 @default.
• W4304136060 creator A5062820627 @default.
• W4304136060 creator A5065978176 @default.
• W4304136060 creator A5087584598 @default.
• W4304136060 date "2022-10-10" @default.
• W4304136060 modified "2023-09-26" @default.
• W4304136060 title "Estimating the impact of drug addiction causes heart damage" @default.
• W4304136060 cites W1964993487 @default.
• W4304136060 cites W1966537913 @default.
• W4304136060 cites W1996599358 @default.
• W4304136060 cites W2010399667 @default.
• W4304136060 cites W2011369409 @default.
• W4304136060 cites W2015639803 @default.
• W4304136060 cites W2022269638 @default.
• W4304136060 cites W2026949272 @default.
• W4304136060 cites W2044372871 @default.
• W4304136060 cites W2047749249 @default.
• W4304136060 cites W2063567825 @default.
• W4304136060 cites W2066253688 @default.
• W4304136060 cites W2067862349 @default.
• W4304136060 cites W2084490045 @default.
• W4304136060 cites W2087549039 @default.
• W4304136060 cites W2088244043 @default.
• W4304136060 cites W2089878975 @default.
• W4304136060 cites W2093004592 @default.
• W4304136060 cites W2093727767 @default.
• W4304136060 cites W2122015416 @default.
• W4304136060 cites W2130656441 @default.
• W4304136060 cites W2140031274 @default.
• W4304136060 cites W2147005862 @default.
• W4304136060 cites W2152090961 @default.
• W4304136060 cites W2169095915 @default.
• W4304136060 cites W2336383135 @default.
• W4304136060 cites W2345592446 @default.
• W4304136060 cites W2463921077 @default.
• W4304136060 cites W2557098740 @default.
• W4304136060 cites W2615764914 @default.
• W4304136060 cites W2782508195 @default.
• W4304136060 cites W2963740889 @default.
• W4304136060 cites W2999983901 @default.
• W4304136060 cites W3014064772 @default.
• W4304136060 cites W3118267397 @default.
• W4304136060 cites W3128552334 @default.
• W4304136060 cites W3162899768 @default.
• W4304136060 cites W4281620537 @default.
• W4304136060 doi "https://doi.org/10.1080/01480545.2022.2122984" @default.
• W4304136060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36216784" @default.
• W4304136060 hasPublicationYear "2022" @default.
• W4304136060 type Work @default.
• W4304136060 citedByCount "0" @default.
• W4304136060 crossrefType "journal-article" @default.
• W4304136060 hasAuthorship W4304136060A5017165971 @default.
• W4304136060 hasAuthorship W4304136060A5024637369 @default.
• W4304136060 hasAuthorship W4304136060A5025462564 @default.
• W4304136060 hasAuthorship W4304136060A5025617602 @default.
• W4304136060 hasAuthorship W4304136060A5046155407 @default.
• W4304136060 hasAuthorship W4304136060A5046900257 @default.
• W4304136060 hasAuthorship W4304136060A5053360201 @default.
• W4304136060 hasAuthorship W4304136060A5062745561 @default.
• W4304136060 hasAuthorship W4304136060A5062820627 @default.
• W4304136060 hasAuthorship W4304136060A5065978176 @default.
• W4304136060 hasAuthorship W4304136060A5087584598 @default.
• W4304136060 hasConcept C118552586 @default.
• W4304136060 hasConcept C126322002 @default.
• W4304136060 hasConcept C134018914 @default.
• W4304136060 hasConcept C2777193897 @default.
• W4304136060 hasConcept C2778903686 @default.
• W4304136060 hasConcept C2780035454 @default.
• W4304136060 hasConcept C2780074459 @default.
• W4304136060 hasConcept C2780687700 @default.
• W4304136060 hasConcept C42407357 @default.
• W4304136060 hasConcept C48856860 @default.
• W4304136060 hasConcept C513476851 @default.
• W4304136060 hasConcept C71924100 @default.
• W4304136060 hasConcept C98274493 @default.
• W4304136060 hasConceptScore W4304136060C118552586 @default.
• W4304136060 hasConceptScore W4304136060C126322002 @default.
• W4304136060 hasConceptScore W4304136060C134018914 @default.
• W4304136060 hasConceptScore W4304136060C2777193897 @default.
• W4304136060 hasConceptScore W4304136060C2778903686 @default.
• W4304136060 hasConceptScore W4304136060C2780035454 @default.
• W4304136060 hasConceptScore W4304136060C2780074459 @default.
• W4304136060 hasConceptScore W4304136060C2780687700 @default.
• W4304136060 hasConceptScore W4304136060C42407357 @default.
• W4304136060 hasConceptScore W4304136060C48856860 @default.
• W4304136060 hasConceptScore W4304136060C513476851 @default.
• W4304136060 hasConceptScore W4304136060C71924100 @default.
• W4304136060 hasConceptScore W4304136060C98274493 @default.
• W4304136060 hasFunder F4320323032 @default.

• next