FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304163261> ?p ?o ?g. }

• W4304163261 abstract "Hypertension is a frequent condition encountered during kidney disease development and a leading cause in its progression. Hallmark factors contributing to hypertension constitute a complexity of events that progress chronic kidney disease (CKD) into end-stage renal disease (ESRD). Multiple crosstalk mechanisms are involved in sustaining the inevitable high blood pressure (BP) state in CKD, and these play an important role in the pathogenesis of increased cardiovascular (CV) events associated with CKD. The present review discusses relevant contributory mechanisms underpinning the promotion of hypertension and their consequent eventuation to renal damage and CV disease. In particular, salt and volume expansion, sympathetic nervous system (SNS) hyperactivity, upregulated renin-angiotensin-aldosterone system (RAAS), oxidative stress, vascular remodeling, endothelial dysfunction, and a range of mediators and signaling molecules which are thought to play a role in this concert of events are emphasized. As the control of high BP via therapeutic interventions can represent the key strategy to not only reduce BP but also the CV burden in kidney disease, evidence for major strategic pathways that can alleviate the progression of hypertensive kidney disease are highlighted. This review provides a particular focus on the impact of RAAS antagonists, renal nerve denervation, baroreflex stimulation, and other modalities affecting BP in the context of CKD, to provide interesting perspectives on the management of hypertensive nephropathy and associated CV comorbidities." @default.
• W4304163261 created "2022-10-11" @default.
• W4304163261 creator A5046484119 @default.
• W4304163261 date "2022-10-11" @default.
• W4304163261 modified "2023-09-30" @default.
• W4304163261 title "Hypertension in chronic kidney disease: What lies behind the scene" @default.
• W4304163261 cites W133084136 @default.
• W4304163261 cites W143205812 @default.
• W4304163261 cites W1489427667 @default.
• W4304163261 cites W1508102251 @default.
• W4304163261 cites W1512521218 @default.
• W4304163261 cites W1547024765 @default.
• W4304163261 cites W1549872837 @default.
• W4304163261 cites W1558440797 @default.
• W4304163261 cites W1583834060 @default.
• W4304163261 cites W1588861005 @default.
• W4304163261 cites W1590434695 @default.
• W4304163261 cites W1598217995 @default.
• W4304163261 cites W1667976360 @default.
• W4304163261 cites W167701172 @default.
• W4304163261 cites W1714940412 @default.
• W4304163261 cites W1718902802 @default.
• W4304163261 cites W1771976347 @default.
• W4304163261 cites W1962462058 @default.
• W4304163261 cites W1964825408 @default.
• W4304163261 cites W1965355084 @default.
• W4304163261 cites W1967972391 @default.
• W4304163261 cites W1968726611 @default.
• W4304163261 cites W1973553081 @default.
• W4304163261 cites W1974077099 @default.
• W4304163261 cites W1974850809 @default.
• W4304163261 cites W1975470640 @default.
• W4304163261 cites W1977528704 @default.
• W4304163261 cites W1977783092 @default.
• W4304163261 cites W1977965797 @default.
• W4304163261 cites W1978911374 @default.
• W4304163261 cites W1980809339 @default.
• W4304163261 cites W1981327055 @default.
• W4304163261 cites W1982282544 @default.
• W4304163261 cites W1983804278 @default.
• W4304163261 cites W1984794690 @default.
• W4304163261 cites W1989254586 @default.
• W4304163261 cites W1990022756 @default.
• W4304163261 cites W1990294083 @default.
• W4304163261 cites W1991210746 @default.
• W4304163261 cites W1991920032 @default.
• W4304163261 cites W1992368579 @default.
• W4304163261 cites W1992390260 @default.
• W4304163261 cites W1993637988 @default.
• W4304163261 cites W1994135647 @default.
• W4304163261 cites W1994506978 @default.
• W4304163261 cites W1995381509 @default.
• W4304163261 cites W1996133577 @default.
• W4304163261 cites W1996510966 @default.
• W4304163261 cites W1996653758 @default.
• W4304163261 cites W1997286719 @default.
• W4304163261 cites W1997592103 @default.
• W4304163261 cites W1997868105 @default.
• W4304163261 cites W2000060059 @default.
• W4304163261 cites W2002288522 @default.
• W4304163261 cites W2002603278 @default.
• W4304163261 cites W2003790156 @default.
• W4304163261 cites W2003972147 @default.
• W4304163261 cites W2004270313 @default.
• W4304163261 cites W2005588918 @default.
• W4304163261 cites W2007943051 @default.
• W4304163261 cites W2009619048 @default.
• W4304163261 cites W2011089437 @default.
• W4304163261 cites W2014844679 @default.
• W4304163261 cites W2015170224 @default.
• W4304163261 cites W2015556579 @default.
• W4304163261 cites W2015794850 @default.
• W4304163261 cites W2018462891 @default.
• W4304163261 cites W2018796965 @default.
• W4304163261 cites W2020584414 @default.
• W4304163261 cites W2020699761 @default.
• W4304163261 cites W2024178248 @default.
• W4304163261 cites W2024848503 @default.
• W4304163261 cites W2025719390 @default.
• W4304163261 cites W2025829800 @default.
• W4304163261 cites W2026798537 @default.
• W4304163261 cites W2027806178 @default.
• W4304163261 cites W2029241241 @default.
• W4304163261 cites W2031026506 @default.
• W4304163261 cites W2032576629 @default.
• W4304163261 cites W2035655266 @default.
• W4304163261 cites W2035943962 @default.
• W4304163261 cites W2037135703 @default.
• W4304163261 cites W2037841947 @default.
• W4304163261 cites W2038408757 @default.
• W4304163261 cites W2039949792 @default.
• W4304163261 cites W2041461323 @default.
• W4304163261 cites W2045494721 @default.
• W4304163261 cites W2047390875 @default.
• W4304163261 cites W2048302860 @default.
• W4304163261 cites W2048320044 @default.
• W4304163261 cites W2048435005 @default.
• W4304163261 cites W2048539937 @default.
• W4304163261 cites W2048592627 @default.
• W4304163261 cites W2048921942 @default.

• next