Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304187411> ?p ?o ?g. }
- W4304187411 abstract "Aims: This study aimed to prepare and physicochemically evaluate as well as assess the cytotoxicity and stimulation of early osteogenic differentiation of dental pulp stem cells of gelatin-hydroxyapatite (Gel-HA) fibrous nanocomposite scaffold. Background: Recently, the electrospinning approach in nanotechnology has been considered due to its application in the preparation of biomimetic nanofibers for tissue engineering. Objective: The main objective of this study was to evaluate Gel-HA fibrous nanocomposite for regenerative dentistry and bone tissue engineering material. Methods: The nano-scaffold was prepared via the electrospinning method. Then, the physicochemical properties (particle size, surface charge, morphology, hydrophilicity, specific surface area, crystalline state and the characterization of functional groups) and the proliferative effects of nano-scaffolds on dental pulp stem cells were assessed. The alkaline phosphatase activity was assessed for evaluation of early osteogenic differentiation of dental pulp stem cells. Results: The prepared nano-scaffolds had a negative surface charge (-30 mv±1.3), mono-dispersed nano-scale diameter (98 nm±1.2), crystalline state and fibrous uniform morphology without any bead (structural defects). The nanofibrous scaffold showed increased hydrophobicity compared to gelatin nanofibers. Based on Brunauer-Emmett-Teller analysis, the specific surface area, pore volume and pore diameter of Gel-HA nanofibers decreased compared to gelatin nanofibers. The Gel-HA nano-fibers showed the proliferative effect and increased the alkaline phosphatase activity of cells significantly (P<0.05). Conclusion: The prepared Gel-HA nanofibers can be considered potential candidates for application in bone tissue engineering and regenerative dentistry. Other: Gel-HA nanofibers could be a potential material for bone regeneration and regenerative dentistry in the near future." @default.
- W4304187411 created "2022-10-11" @default.
- W4304187411 creator A5024091208 @default.
- W4304187411 creator A5026048457 @default.
- W4304187411 creator A5028557055 @default.
- W4304187411 creator A5047867776 @default.
- W4304187411 creator A5062166832 @default.
- W4304187411 date "2022-10-11" @default.
- W4304187411 modified "2023-09-30" @default.
- W4304187411 title "Gelatin-hydroxyapatite Fibrous Nanocomposite for Regenerative Dentistry and bone Tissue Engineering" @default.
- W4304187411 cites W1898130976 @default.
- W4304187411 cites W1974873948 @default.
- W4304187411 cites W1978196655 @default.
- W4304187411 cites W1999318759 @default.
- W4304187411 cites W2013459939 @default.
- W4304187411 cites W2032187006 @default.
- W4304187411 cites W2034878796 @default.
- W4304187411 cites W2048203157 @default.
- W4304187411 cites W2054022426 @default.
- W4304187411 cites W2068076106 @default.
- W4304187411 cites W2076065085 @default.
- W4304187411 cites W2111195311 @default.
- W4304187411 cites W2114035952 @default.
- W4304187411 cites W2160018954 @default.
- W4304187411 cites W2397131438 @default.
- W4304187411 cites W2402337764 @default.
- W4304187411 cites W2567525360 @default.
- W4304187411 cites W2587988584 @default.
- W4304187411 cites W2617276432 @default.
- W4304187411 cites W2793045677 @default.
- W4304187411 cites W2808973838 @default.
- W4304187411 cites W2885582644 @default.
- W4304187411 cites W2889438766 @default.
- W4304187411 cites W2889714474 @default.
- W4304187411 cites W2893267824 @default.
- W4304187411 cites W2903146197 @default.
- W4304187411 cites W2904738292 @default.
- W4304187411 cites W2912816164 @default.
- W4304187411 cites W2916279213 @default.
- W4304187411 cites W2920060179 @default.
- W4304187411 cites W2944784158 @default.
- W4304187411 cites W2949704821 @default.
- W4304187411 cites W2955498209 @default.
- W4304187411 cites W2968632405 @default.
- W4304187411 cites W2969535285 @default.
- W4304187411 cites W2969759217 @default.
- W4304187411 cites W2979851760 @default.
- W4304187411 cites W3018712837 @default.
- W4304187411 cites W3033001486 @default.
- W4304187411 cites W3033225111 @default.
- W4304187411 cites W3049134750 @default.
- W4304187411 cites W3089573375 @default.
- W4304187411 cites W3092088581 @default.
- W4304187411 cites W3093760486 @default.
- W4304187411 cites W3099560583 @default.
- W4304187411 cites W3114059087 @default.
- W4304187411 cites W3118523306 @default.
- W4304187411 cites W3163747386 @default.
- W4304187411 cites W3172846931 @default.
- W4304187411 cites W3184503759 @default.
- W4304187411 cites W4200624586 @default.
- W4304187411 cites W4211241235 @default.
- W4304187411 doi "https://doi.org/10.2174/18742106-v16-e2208200" @default.
- W4304187411 hasPublicationYear "2022" @default.
- W4304187411 type Work @default.
- W4304187411 citedByCount "0" @default.
- W4304187411 crossrefType "journal-article" @default.
- W4304187411 hasAuthorship W4304187411A5024091208 @default.
- W4304187411 hasAuthorship W4304187411A5026048457 @default.
- W4304187411 hasAuthorship W4304187411A5028557055 @default.
- W4304187411 hasAuthorship W4304187411A5047867776 @default.
- W4304187411 hasAuthorship W4304187411A5062166832 @default.
- W4304187411 hasBestOaLocation W43041874111 @default.
- W4304187411 hasConcept C136229726 @default.
- W4304187411 hasConcept C144796933 @default.
- W4304187411 hasConcept C159985019 @default.
- W4304187411 hasConcept C160160445 @default.
- W4304187411 hasConcept C171250308 @default.
- W4304187411 hasConcept C181199279 @default.
- W4304187411 hasConcept C185592680 @default.
- W4304187411 hasConcept C192562407 @default.
- W4304187411 hasConcept C199343813 @default.
- W4304187411 hasConcept C202751555 @default.
- W4304187411 hasConcept C2777400515 @default.
- W4304187411 hasConcept C2778823387 @default.
- W4304187411 hasConcept C49892992 @default.
- W4304187411 hasConcept C521977710 @default.
- W4304187411 hasConcept C55493867 @default.
- W4304187411 hasConcept C71924100 @default.
- W4304187411 hasConcept C89429830 @default.
- W4304187411 hasConcept C91129048 @default.
- W4304187411 hasConcept C92880739 @default.
- W4304187411 hasConceptScore W4304187411C136229726 @default.
- W4304187411 hasConceptScore W4304187411C144796933 @default.
- W4304187411 hasConceptScore W4304187411C159985019 @default.
- W4304187411 hasConceptScore W4304187411C160160445 @default.
- W4304187411 hasConceptScore W4304187411C171250308 @default.
- W4304187411 hasConceptScore W4304187411C181199279 @default.
- W4304187411 hasConceptScore W4304187411C185592680 @default.
- W4304187411 hasConceptScore W4304187411C192562407 @default.