FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304191898> ?p ?o ?g. }

• W4304191898 endingPage "e42585" @default.
• W4304191898 startingPage "e42585" @default.
• W4304191898 abstract "Background The ongoing volatile opioid epidemic remains a significant public health concern, alongside continued outbreaks of HIV and hepatitis C virus among people who inject drugs. The limited access to and scale-up of medications for opioid use disorder (MOUD) among people who inject drugs, coupled with multilevel barriers to pre-exposure prophylaxis (PrEP) uptake, makes it imperative to integrate evidence-based risk reduction and HIV prevention strategies in innovative ways. To address this need, we developed an integrated rapid access to HIV prevention program for people who inject drugs (iRaPID) that incorporates same-day PrEP and MOUD for this population. Objective The primary objective of this pilot study is to assess the feasibility and acceptability of the program and evaluate its preliminary efficacy on PrEP and MOUD uptake for a future randomized controlled trial (RCT). We also aim to explore information on the implementation of the program in a real-world setting using a type I hybrid implementation trial design. Methods Using a type I hybrid implementation trial design, we are pilot testing the nurse practitioner–led iRaPID program while exploring information on its implementation in a real-world setting. Specifically, we will assess the feasibility and acceptability of the iRaPID program and evaluate its preliminary efficacy on PrEP and MOUD uptake in a pilot RCT. The enrolled 50 people who inject drugs will be randomized (1:1) to either iRaPID or treatment as usual (TAU). Behavioral assessments will occur at baseline, and at 1, 3, and 6 months. Additionally, we will conduct a process evaluation of the delivery and implementation of the iRaPID program to collect information for future implementation. Results Recruitment began in July 2021 and was completed in August 2022. Data collection is planned through February 2023. The Institutional Review Boards at Yale University and the University of Connecticut approved this study (2000028740). Conclusions This prospective pilot study will test a nurse practitioner–led, integrated HIV prevention program that incorporates same-day PrEP and MOUD for people who inject drugs. This low-threshold protocol delivers integrated prevention via one-stop shopping under the direction of nurse practitioners. iRaPID seeks to overcome barriers to delayed PrEP and MOUD initiation, which is crucial for people who inject drugs who have had minimal access to evidence-based prevention. Trial Registration ClinicalTrials.gov NCT04531670; https://clinicaltrials.gov/ct2/show/NCT04531670 International Registered Report Identifier (IRRID) DERR1-10.2196/42585" @default.
• W4304191898 created "2022-10-11" @default.
• W4304191898 creator A5006243971 @default.
• W4304191898 creator A5007238225 @default.
• W4304191898 creator A5007606082 @default.
• W4304191898 creator A5021494352 @default.
• W4304191898 creator A5034022794 @default.
• W4304191898 creator A5038392101 @default.
• W4304191898 creator A5044840931 @default.
• W4304191898 creator A5058849441 @default.
• W4304191898 creator A5060254817 @default.
• W4304191898 creator A5063209435 @default.
• W4304191898 date "2022-10-11" @default.
• W4304191898 modified "2023-10-14" @default.
• W4304191898 title "Nurse Practitioner–Led Integrated Rapid Access to HIV Prevention for People Who Inject Drugs (iRaPID): Protocol for a Pilot Randomized Controlled Trial" @default.
• W4304191898 cites W1724694251 @default.
• W4304191898 cites W1952259858 @default.
• W4304191898 cites W1965388675 @default.
• W4304191898 cites W1971540772 @default.
• W4304191898 cites W1979089942 @default.
• W4304191898 cites W1989807443 @default.
• W4304191898 cites W1999480157 @default.
• W4304191898 cites W2005325503 @default.
• W4304191898 cites W2011363763 @default.
• W4304191898 cites W2039503871 @default.
• W4304191898 cites W2044619545 @default.
• W4304191898 cites W2057716417 @default.
• W4304191898 cites W2059730204 @default.
• W4304191898 cites W2063739166 @default.
• W4304191898 cites W2065813340 @default.
• W4304191898 cites W2094645425 @default.
• W4304191898 cites W2101924020 @default.
• W4304191898 cites W2115188769 @default.
• W4304191898 cites W2117818945 @default.
• W4304191898 cites W2118743377 @default.
• W4304191898 cites W2132974770 @default.
• W4304191898 cites W2134458339 @default.
• W4304191898 cites W2143001335 @default.
• W4304191898 cites W2146795731 @default.
• W4304191898 cites W2153796879 @default.
• W4304191898 cites W2158702615 @default.
• W4304191898 cites W2305604517 @default.
• W4304191898 cites W2329324888 @default.
• W4304191898 cites W2334201740 @default.
• W4304191898 cites W2338238134 @default.
• W4304191898 cites W2412852451 @default.
• W4304191898 cites W2466146762 @default.
• W4304191898 cites W2470822429 @default.
• W4304191898 cites W2514546776 @default.
• W4304191898 cites W2533184263 @default.
• W4304191898 cites W2554190977 @default.
• W4304191898 cites W2557642610 @default.
• W4304191898 cites W2594572380 @default.
• W4304191898 cites W2613370096 @default.
• W4304191898 cites W2614824983 @default.
• W4304191898 cites W2743331583 @default.
• W4304191898 cites W2746467818 @default.
• W4304191898 cites W2746887775 @default.
• W4304191898 cites W2750910194 @default.
• W4304191898 cites W2765091655 @default.
• W4304191898 cites W2768611407 @default.
• W4304191898 cites W2794931281 @default.
• W4304191898 cites W2795178149 @default.
• W4304191898 cites W2804237879 @default.
• W4304191898 cites W2889644859 @default.
• W4304191898 cites W2890429763 @default.
• W4304191898 cites W2895909318 @default.
• W4304191898 cites W2911490965 @default.
• W4304191898 cites W2914851967 @default.
• W4304191898 cites W2927856564 @default.
• W4304191898 cites W2937384782 @default.
• W4304191898 cites W2954876968 @default.
• W4304191898 cites W2987866502 @default.
• W4304191898 cites W2994625237 @default.
• W4304191898 cites W3000270651 @default.
• W4304191898 cites W3044927684 @default.
• W4304191898 cites W3046406812 @default.
• W4304191898 cites W3096370392 @default.
• W4304191898 cites W3109847459 @default.
• W4304191898 cites W3132813327 @default.
• W4304191898 cites W3137914276 @default.
• W4304191898 cites W3190424399 @default.
• W4304191898 cites W3205235034 @default.
• W4304191898 cites W3206071471 @default.
• W4304191898 cites W4220881240 @default.
• W4304191898 cites W4280565035 @default.
• W4304191898 doi "https://doi.org/10.2196/42585" @default.
• W4304191898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36222826" @default.
• W4304191898 hasPublicationYear "2022" @default.
• W4304191898 type Work @default.
• W4304191898 citedByCount "1" @default.
• W4304191898 countsByYear W43041918982022 @default.
• W4304191898 crossrefType "journal-article" @default.
• W4304191898 hasAuthorship W4304191898A5006243971 @default.
• W4304191898 hasAuthorship W4304191898A5007238225 @default.
• W4304191898 hasAuthorship W4304191898A5007606082 @default.
• W4304191898 hasAuthorship W4304191898A5021494352 @default.
• W4304191898 hasAuthorship W4304191898A5034022794 @default.

• next