FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304203431> ?p ?o ?g. }

• W4304203431 abstract "Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease with irreversible and continuous progression. It has become the fifth most burdensome disease and the third most deadly disease globally. Therefore, the prevention and treatment of COPD are urgent, and it is also important to clarify the pathogenesis of it. Smoking is the main and most common risk factor for COPD. Cigarette smoke (CS) can cause lung inflammation and other pathological mechanisms in the airways and lung tissue. Airway inflammation is one of the important mechanisms leading to the pathogenesis of COPD. Recent studies have shown that high mobility group box 1 (HMGB1) is involved in the occurrence and development of respiratory diseases, including COPD. HMGB1 is a typical damage-associated molecular pattern (DAMP) protein, which mainly exerts its activity by binding to the receptor for advanced glycation end products (RAGE) and toll-like receptor 4 (TLR4) and further participate in the process of airway inflammation. Studies have shown that the abnormal expression of HMGB1, RAGE, and TLR4 are related to inflammation in COPD. Herein, we discuss the roles of HMGB1, RAGE, and TLR4 in CS/cigarette smoke extract-induced inflammation in COPD, providing a new target for the diagnosis, treatment and prevention of COPD." @default.
• W4304203431 created "2022-10-11" @default.
• W4304203431 creator A5011141266 @default.
• W4304203431 creator A5012677271 @default.
• W4304203431 creator A5013072436 @default.
• W4304203431 creator A5040650909 @default.
• W4304203431 creator A5077947540 @default.
• W4304203431 date "2022-10-11" @default.
• W4304203431 modified "2023-10-14" @default.
• W4304203431 title "The role of HMGB1/RAGE/TLR4 signaling pathways in cigarette smoke‐induced inflammation in chronic obstructive pulmonary disease" @default.
• W4304203431 cites W103801910 @default.
• W4304203431 cites W1490762074 @default.
• W4304203431 cites W1542857544 @default.
• W4304203431 cites W1590156932 @default.
• W4304203431 cites W1747652534 @default.
• W4304203431 cites W1828520970 @default.
• W4304203431 cites W1847056372 @default.
• W4304203431 cites W1931590068 @default.
• W4304203431 cites W1965891167 @default.
• W4304203431 cites W1966235050 @default.
• W4304203431 cites W1967393044 @default.
• W4304203431 cites W1970801712 @default.
• W4304203431 cites W1973312267 @default.
• W4304203431 cites W1974972632 @default.
• W4304203431 cites W1981010107 @default.
• W4304203431 cites W1984830754 @default.
• W4304203431 cites W1989289468 @default.
• W4304203431 cites W1989329537 @default.
• W4304203431 cites W1992944558 @default.
• W4304203431 cites W1993005570 @default.
• W4304203431 cites W1994190235 @default.
• W4304203431 cites W1998224383 @default.
• W4304203431 cites W2002246184 @default.
• W4304203431 cites W2004927458 @default.
• W4304203431 cites W2008239392 @default.
• W4304203431 cites W2008778288 @default.
• W4304203431 cites W2020840750 @default.
• W4304203431 cites W2022727685 @default.
• W4304203431 cites W2026885016 @default.
• W4304203431 cites W2029068688 @default.
• W4304203431 cites W2029346951 @default.
• W4304203431 cites W2029561500 @default.
• W4304203431 cites W2032026196 @default.
• W4304203431 cites W2035649296 @default.
• W4304203431 cites W2047948148 @default.
• W4304203431 cites W2049029258 @default.
• W4304203431 cites W2049871145 @default.
• W4304203431 cites W2052419059 @default.
• W4304203431 cites W2053517795 @default.
• W4304203431 cites W2069465034 @default.
• W4304203431 cites W2075035271 @default.
• W4304203431 cites W2079112084 @default.
• W4304203431 cites W2080183381 @default.
• W4304203431 cites W2086327676 @default.
• W4304203431 cites W2088310198 @default.
• W4304203431 cites W2093789959 @default.
• W4304203431 cites W2106039427 @default.
• W4304203431 cites W2109590683 @default.
• W4304203431 cites W2113468396 @default.
• W4304203431 cites W2117796628 @default.
• W4304203431 cites W2120476106 @default.
• W4304203431 cites W2123608437 @default.
• W4304203431 cites W2126420549 @default.
• W4304203431 cites W2131165238 @default.
• W4304203431 cites W2143239934 @default.
• W4304203431 cites W2143263732 @default.
• W4304203431 cites W2144015888 @default.
• W4304203431 cites W2154194339 @default.
• W4304203431 cites W2157404235 @default.
• W4304203431 cites W2160960292 @default.
• W4304203431 cites W2161528116 @default.
• W4304203431 cites W2162182198 @default.
• W4304203431 cites W2163550534 @default.
• W4304203431 cites W2164618384 @default.
• W4304203431 cites W2164970501 @default.
• W4304203431 cites W2165410977 @default.
• W4304203431 cites W2170688086 @default.
• W4304203431 cites W2198703234 @default.
• W4304203431 cites W2204595052 @default.
• W4304203431 cites W2218664020 @default.
• W4304203431 cites W2282960387 @default.
• W4304203431 cites W2315092288 @default.
• W4304203431 cites W2324917897 @default.
• W4304203431 cites W2395320478 @default.
• W4304203431 cites W2401306489 @default.
• W4304203431 cites W2410130417 @default.
• W4304203431 cites W2539344253 @default.
• W4304203431 cites W2548624887 @default.
• W4304203431 cites W2555875150 @default.
• W4304203431 cites W2561612116 @default.
• W4304203431 cites W2563386262 @default.
• W4304203431 cites W2570738774 @default.
• W4304203431 cites W2584023838 @default.
• W4304203431 cites W2590701429 @default.
• W4304203431 cites W2607275024 @default.
• W4304203431 cites W2619076532 @default.
• W4304203431 cites W2736859780 @default.
• W4304203431 cites W2737662840 @default.
• W4304203431 cites W2739498582 @default.
• W4304203431 cites W2747666769 @default.

• next