Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304585359> ?p ?o ?g. }
- W4304585359 endingPage "4985" @default.
- W4304585359 startingPage "4985" @default.
- W4304585359 abstract "Recently, considerable progress has been achieved in cancer immunotherapy. Targeted immune checkpoint therapies have been established for several forms of cancers, which resulted in a tremendous positive impact on patient survival, even in more advanced tumor stages. With a better understanding of cellular responses to immune checkpoint therapies, it will soon be feasible to find targeted compounds which will make personalized medicine practicable. This is a great opportunity, but it also sets tremendous challenges on both the scientific and clinical aspects. Head and neck tumors evade immune surveillance through various mechanisms. They contain fewer lymphocytes (natural killer cells) than normal tissue with an accumulation of immunosuppressive regulatory T cells. Standard therapies for HNSCC, such as surgery, radiation, and chemotherapy, are becoming more advantageous by targeting immune checkpoints and employing combination therapies. The purpose of this review is to provide an overview of the expanded therapeutic options, particularly the combination of immune checkpoint inhibition with various conventional and novel therapeutics for head and neck tumor patients." @default.
- W4304585359 created "2022-10-12" @default.
- W4304585359 creator A5033513615 @default.
- W4304585359 creator A5043373358 @default.
- W4304585359 creator A5062484236 @default.
- W4304585359 creator A5087467494 @default.
- W4304585359 date "2022-10-11" @default.
- W4304585359 modified "2023-10-15" @default.
- W4304585359 title "Checkpoint Inhibitors in Cancer Therapy: Clinical Benefits for Head and Neck Cancers" @default.
- W4304585359 cites W1488814076 @default.
- W4304585359 cites W1498931318 @default.
- W4304585359 cites W1815115486 @default.
- W4304585359 cites W1820495241 @default.
- W4304585359 cites W1821185514 @default.
- W4304585359 cites W1869500669 @default.
- W4304585359 cites W1881296535 @default.
- W4304585359 cites W1900099842 @default.
- W4304585359 cites W1963665993 @default.
- W4304585359 cites W1966064788 @default.
- W4304585359 cites W1966285815 @default.
- W4304585359 cites W1976926341 @default.
- W4304585359 cites W1978758070 @default.
- W4304585359 cites W1979103878 @default.
- W4304585359 cites W1984545852 @default.
- W4304585359 cites W1988474688 @default.
- W4304585359 cites W1989754098 @default.
- W4304585359 cites W1992249154 @default.
- W4304585359 cites W2017712207 @default.
- W4304585359 cites W2023630604 @default.
- W4304585359 cites W2027538916 @default.
- W4304585359 cites W2029101596 @default.
- W4304585359 cites W2029566727 @default.
- W4304585359 cites W2033932056 @default.
- W4304585359 cites W2036117709 @default.
- W4304585359 cites W2041629407 @default.
- W4304585359 cites W2049553585 @default.
- W4304585359 cites W2055284977 @default.
- W4304585359 cites W2055390961 @default.
- W4304585359 cites W2067118084 @default.
- W4304585359 cites W2076652911 @default.
- W4304585359 cites W2081553653 @default.
- W4304585359 cites W2086946343 @default.
- W4304585359 cites W2087526226 @default.
- W4304585359 cites W2098028863 @default.
- W4304585359 cites W2101760255 @default.
- W4304585359 cites W2102095362 @default.
- W4304585359 cites W2102833781 @default.
- W4304585359 cites W2107075226 @default.
- W4304585359 cites W2107484016 @default.
- W4304585359 cites W2109274792 @default.
- W4304585359 cites W2112845420 @default.
- W4304585359 cites W2114443495 @default.
- W4304585359 cites W2115307546 @default.
- W4304585359 cites W2117328669 @default.
- W4304585359 cites W2117692326 @default.
- W4304585359 cites W2118396147 @default.
- W4304585359 cites W2121071739 @default.
- W4304585359 cites W2124427232 @default.
- W4304585359 cites W2127055182 @default.
- W4304585359 cites W2131971625 @default.
- W4304585359 cites W2141186092 @default.
- W4304585359 cites W2143265289 @default.
- W4304585359 cites W2143772132 @default.
- W4304585359 cites W2144431766 @default.
- W4304585359 cites W2151213561 @default.
- W4304585359 cites W2159094759 @default.
- W4304585359 cites W2163196794 @default.
- W4304585359 cites W2163814058 @default.
- W4304585359 cites W2175965103 @default.
- W4304585359 cites W2176667622 @default.
- W4304585359 cites W2183585286 @default.
- W4304585359 cites W2201379305 @default.
- W4304585359 cites W2217300711 @default.
- W4304585359 cites W2280151081 @default.
- W4304585359 cites W2282664279 @default.
- W4304585359 cites W2284998884 @default.
- W4304585359 cites W2335332412 @default.
- W4304585359 cites W2345568581 @default.
- W4304585359 cites W2345835165 @default.
- W4304585359 cites W2386935098 @default.
- W4304585359 cites W2401455386 @default.
- W4304585359 cites W2510493372 @default.
- W4304585359 cites W2523194272 @default.
- W4304585359 cites W2529484692 @default.
- W4304585359 cites W2537963082 @default.
- W4304585359 cites W2548444198 @default.
- W4304585359 cites W2549481046 @default.
- W4304585359 cites W2560367415 @default.
- W4304585359 cites W2572174216 @default.
- W4304585359 cites W2585352231 @default.
- W4304585359 cites W2586937224 @default.
- W4304585359 cites W2588255011 @default.
- W4304585359 cites W2594700923 @default.
- W4304585359 cites W2604266972 @default.
- W4304585359 cites W2607191617 @default.
- W4304585359 cites W2615301036 @default.
- W4304585359 cites W2618327597 @default.
- W4304585359 cites W2622219590 @default.