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• W4304607260 abstract "Abstract Speed is key during infectious disease outbreaks. It is essential, for example, to identify critical host binding factors to the pathogens as fast as possible. The complexity of host plasma membrane is often a limiting factor hindering fast and accurate determination of host binding factors as well as high-throughput screening for neutralizing antimicrobial drug targets. Here we describe MIGH-T, a multi-parametric and high-throughput platform tackling this bottleneck and enabling fast screens for host binding factors as well as new antiviral drug targets. The sensitivity and robustness of our platform was validated by blocking SARS-CoV-2 spike particles with nanobodies and IgGs from human serum samples." @default.
• W4304607260 created "2022-10-12" @default.
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• W4304607260 date "2022-10-11" @default.
• W4304607260 modified "2023-10-18" @default.
• W4304607260 title "MIGH-T – A Multi-Parametric and High-Throughput Platform for Host-Virus Binding Screens" @default.
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• W4304607260 doi "https://doi.org/10.1101/2022.10.10.511545" @default.
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