FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304694268> ?p ?o ?g. }

• W4304694268 abstract "Chlorella spp., Spirulina spp., and fucoidan dry powders, are commercialized as food supplements and are considered safe for human consumption. Their broad-spectrum antiviral properties have been studied, however, their effect against SARS-CoV-2 remains unknown. We investigated the potential antiviral activity of three algae powders: Chlorella vulgaris, Arthrospira maxima (Spirulina) and fucoidan purified from marine brown algae Sargassum spp. against SARS-CoV-2 infection in vitro. Vero cells were incubated with 70 μg/ml of each algae powder and either 50 or 100 TCID50/ml of SARS-CoV-2, in two types of experiments (pretreatment and simultaneous) and comparing two kinds of solvents (DMEM and DMSO). Chlorella vulgaris powder, inhibited SARS-CoV-2 infection in all assays; viral RNA was significantly reduced in supernatants at 24, 48, 72, and 96 h post-infection, the highest difference in viral load (8000-fold) was observed after 96 h. Arthrospira maxima powder inhibited SARS-CoV-2 infection using 50 TCID50/ml for both experimental schemes, but protection percent was lower when viral inoculum was increase to 100 TCID50/ml; viral RNA decreased 48 h after infection, reaching a 250-fold difference at 72 h. Fucoidan powder partially inhibited SARS-CoV-2 infection since no CPE was observed in 62.5% of trated cultures in DMEM, but the antiviral activity was increased to 100% of protection when DMSO was used as solvent. All the algae samples showed high antiviral activity against SARS-CoV-2 with a SI above of 18. These results suggest that all three algae samples are potential therapeutic candidates for the treatment of COVID-19." @default.
• W4304694268 created "2022-10-12" @default.
• W4304694268 creator A5033896110 @default.
• W4304694268 creator A5052642068 @default.
• W4304694268 creator A5056611826 @default.
• W4304694268 creator A5089939996 @default.
• W4304694268 date "2022-10-12" @default.
• W4304694268 modified "2023-10-17" @default.
• W4304694268 title "In vitro inhibition of SARS-CoV-2 Infection by dry algae powders" @default.
• W4304694268 cites W1963874329 @default.
• W4304694268 cites W1972685257 @default.
• W4304694268 cites W1974599834 @default.
• W4304694268 cites W1992403094 @default.
• W4304694268 cites W2005150070 @default.
• W4304694268 cites W2026261205 @default.
• W4304694268 cites W2031422991 @default.
• W4304694268 cites W2036422574 @default.
• W4304694268 cites W2126535317 @default.
• W4304694268 cites W2136414263 @default.
• W4304694268 cites W2551400711 @default.
• W4304694268 cites W2885829958 @default.
• W4304694268 cites W2980465288 @default.
• W4304694268 cites W3004303422 @default.
• W4304694268 cites W3004318991 @default.
• W4304694268 cites W3018037557 @default.
• W4304694268 cites W3026271934 @default.
• W4304694268 cites W3036391214 @default.
• W4304694268 cites W3080092764 @default.
• W4304694268 cites W3081667723 @default.
• W4304694268 cites W3087242436 @default.
• W4304694268 cites W3093862692 @default.
• W4304694268 cites W3117340327 @default.
• W4304694268 cites W3132999071 @default.
• W4304694268 cites W3138279754 @default.
• W4304694268 cites W3143941394 @default.
• W4304694268 cites W3153636933 @default.
• W4304694268 cites W3157898654 @default.
• W4304694268 cites W3158210316 @default.
• W4304694268 cites W3174014221 @default.
• W4304694268 cites W3191934781 @default.
• W4304694268 cites W3202134042 @default.
• W4304694268 cites W3208789597 @default.
• W4304694268 cites W3209833474 @default.
• W4304694268 cites W3214297587 @default.
• W4304694268 cites W3216580572 @default.
• W4304694268 cites W4200113113 @default.
• W4304694268 cites W4206934123 @default.
• W4304694268 cites W4210488586 @default.
• W4304694268 doi "https://doi.org/10.1038/s41598-022-22148-6" @default.
• W4304694268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36224327" @default.
• W4304694268 hasPublicationYear "2022" @default.
• W4304694268 type Work @default.
• W4304694268 citedByCount "4" @default.
• W4304694268 countsByYear W43046942682023 @default.
• W4304694268 crossrefType "journal-article" @default.
• W4304694268 hasAuthorship W4304694268A5033896110 @default.
• W4304694268 hasAuthorship W4304694268A5052642068 @default.
• W4304694268 hasAuthorship W4304694268A5056611826 @default.
• W4304694268 hasAuthorship W4304694268A5089939996 @default.
• W4304694268 hasBestOaLocation W43046942681 @default.
• W4304694268 hasConcept C100817775 @default.
• W4304694268 hasConcept C18903297 @default.
• W4304694268 hasConcept C202751555 @default.
• W4304694268 hasConcept C206139338 @default.
• W4304694268 hasConcept C2775909754 @default.
• W4304694268 hasConcept C2778760044 @default.
• W4304694268 hasConcept C2779669040 @default.
• W4304694268 hasConcept C2779784034 @default.
• W4304694268 hasConcept C2781274799 @default.
• W4304694268 hasConcept C2992619708 @default.
• W4304694268 hasConcept C31903555 @default.
• W4304694268 hasConcept C522721590 @default.
• W4304694268 hasConcept C523546767 @default.
• W4304694268 hasConcept C54355233 @default.
• W4304694268 hasConcept C55493867 @default.
• W4304694268 hasConcept C559758991 @default.
• W4304694268 hasConcept C59822182 @default.
• W4304694268 hasConcept C86803240 @default.
• W4304694268 hasConcept C89138240 @default.
• W4304694268 hasConcept C89423630 @default.
• W4304694268 hasConceptScore W4304694268C100817775 @default.
• W4304694268 hasConceptScore W4304694268C18903297 @default.
• W4304694268 hasConceptScore W4304694268C202751555 @default.
• W4304694268 hasConceptScore W4304694268C206139338 @default.
• W4304694268 hasConceptScore W4304694268C2775909754 @default.
• W4304694268 hasConceptScore W4304694268C2778760044 @default.
• W4304694268 hasConceptScore W4304694268C2779669040 @default.
• W4304694268 hasConceptScore W4304694268C2779784034 @default.
• W4304694268 hasConceptScore W4304694268C2781274799 @default.
• W4304694268 hasConceptScore W4304694268C2992619708 @default.
• W4304694268 hasConceptScore W4304694268C31903555 @default.
• W4304694268 hasConceptScore W4304694268C522721590 @default.
• W4304694268 hasConceptScore W4304694268C523546767 @default.
• W4304694268 hasConceptScore W4304694268C54355233 @default.
• W4304694268 hasConceptScore W4304694268C55493867 @default.
• W4304694268 hasConceptScore W4304694268C559758991 @default.
• W4304694268 hasConceptScore W4304694268C59822182 @default.
• W4304694268 hasConceptScore W4304694268C86803240 @default.
• W4304694268 hasConceptScore W4304694268C89138240 @default.
• W4304694268 hasConceptScore W4304694268C89423630 @default.

• next