Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304758014> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4304758014 endingPage "23" @default.
- W4304758014 startingPage "17" @default.
- W4304758014 abstract "Background: Oral chemotherapy nonadherence is a challenge in clinical oncology. During therapy for acute lymphoblastic leukemia (ALL), poor adherence to 6-mercaptopurine (6MP) increases relapse risk. Clinically significant nonadherence is reported in 30% of children treated for ALL on Children's Oncology Group (COG) trials. Whether nonadherence rates vary across regimens with different treatment schedules and modes of administration is unknown. Methods: We conducted an exploratory, cross-sectional survey study on parents of children (1-18 years) receiving continuation therapy on, or as per Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 11-001. Treatment required weekly visits to the clinic and 14 days of oral 6MP every 3 weeks. Survey assessed self-reported sociodemographics, medication-taking, chemotherapy comprehension, and 6MP adherence; adherence survey items were developed from published surveys. Patients were grouped as nonadherent if they endorsed missing one 6MP dose during the last cycle, or more than one dose during prior cycles, for nonmedical reasons. Results: Sixty-two families completed the surveys, all of whom had evaluable adherence data. In total, 25% of patients met the study definition of nonadherence. Twenty-three percent reported that it was not easy to follow administration guidelines around the dairy intake and 57% requested more teaching and educational resources. Conclusion: Self-reported nonadherence to oral 6MP in the DFCI ALL Consortium is high, with rates similar to those observed in the COG. This suggests that the additional contact during weekly infusions on the DFCI is insufficient to address barriers affecting oral chemotherapy adherence." @default.
- W4304758014 created "2022-10-13" @default.
- W4304758014 creator A5002930435 @default.
- W4304758014 creator A5010249866 @default.
- W4304758014 creator A5038675629 @default.
- W4304758014 creator A5041624249 @default.
- W4304758014 creator A5048748466 @default.
- W4304758014 creator A5050678292 @default.
- W4304758014 creator A5053651370 @default.
- W4304758014 creator A5059056112 @default.
- W4304758014 creator A5077589186 @default.
- W4304758014 creator A5087504195 @default.
- W4304758014 creator A5089358491 @default.
- W4304758014 date "2022-10-12" @default.
- W4304758014 modified "2023-10-14" @default.
- W4304758014 title "Oral Mercaptopurine Adherence in Pediatric Acute Lymphoblastic Leukemia: A Survey Study From the Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium" @default.
- W4304758014 cites W1881676016 @default.
- W4304758014 cites W1972467214 @default.
- W4304758014 cites W1979305378 @default.
- W4304758014 cites W2030049579 @default.
- W4304758014 cites W2070741569 @default.
- W4304758014 cites W2103564256 @default.
- W4304758014 cites W2162139369 @default.
- W4304758014 cites W2272486312 @default.
- W4304758014 cites W2417735660 @default.
- W4304758014 cites W2488714789 @default.
- W4304758014 cites W2544857927 @default.
- W4304758014 cites W2584404070 @default.
- W4304758014 cites W2597868456 @default.
- W4304758014 cites W2811286257 @default.
- W4304758014 cites W2997265561 @default.
- W4304758014 cites W3205215515 @default.
- W4304758014 doi "https://doi.org/10.1177/27527530221122685" @default.
- W4304758014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36221984" @default.
- W4304758014 hasPublicationYear "2022" @default.
- W4304758014 type Work @default.
- W4304758014 citedByCount "0" @default.
- W4304758014 crossrefType "journal-article" @default.
- W4304758014 hasAuthorship W4304758014A5002930435 @default.
- W4304758014 hasAuthorship W4304758014A5010249866 @default.
- W4304758014 hasAuthorship W4304758014A5038675629 @default.
- W4304758014 hasAuthorship W4304758014A5041624249 @default.
- W4304758014 hasAuthorship W4304758014A5048748466 @default.
- W4304758014 hasAuthorship W4304758014A5050678292 @default.
- W4304758014 hasAuthorship W4304758014A5053651370 @default.
- W4304758014 hasAuthorship W4304758014A5059056112 @default.
- W4304758014 hasAuthorship W4304758014A5077589186 @default.
- W4304758014 hasAuthorship W4304758014A5087504195 @default.
- W4304758014 hasAuthorship W4304758014A5089358491 @default.
- W4304758014 hasConcept C121608353 @default.
- W4304758014 hasConcept C126322002 @default.
- W4304758014 hasConcept C187212893 @default.
- W4304758014 hasConcept C2776694085 @default.
- W4304758014 hasConcept C2777173762 @default.
- W4304758014 hasConcept C2778461978 @default.
- W4304758014 hasConcept C2781107101 @default.
- W4304758014 hasConcept C2909962599 @default.
- W4304758014 hasConcept C535046627 @default.
- W4304758014 hasConcept C71924100 @default.
- W4304758014 hasConceptScore W4304758014C121608353 @default.
- W4304758014 hasConceptScore W4304758014C126322002 @default.
- W4304758014 hasConceptScore W4304758014C187212893 @default.
- W4304758014 hasConceptScore W4304758014C2776694085 @default.
- W4304758014 hasConceptScore W4304758014C2777173762 @default.
- W4304758014 hasConceptScore W4304758014C2778461978 @default.
- W4304758014 hasConceptScore W4304758014C2781107101 @default.
- W4304758014 hasConceptScore W4304758014C2909962599 @default.
- W4304758014 hasConceptScore W4304758014C535046627 @default.
- W4304758014 hasConceptScore W4304758014C71924100 @default.
- W4304758014 hasFunder F4320337351 @default.
- W4304758014 hasIssue "1" @default.
- W4304758014 hasLocation W43047580141 @default.
- W4304758014 hasLocation W43047580142 @default.
- W4304758014 hasOpenAccess W4304758014 @default.
- W4304758014 hasPrimaryLocation W43047580141 @default.
- W4304758014 hasRelatedWork W1526681768 @default.
- W4304758014 hasRelatedWork W170801347 @default.
- W4304758014 hasRelatedWork W1995903260 @default.
- W4304758014 hasRelatedWork W2060104469 @default.
- W4304758014 hasRelatedWork W2150118645 @default.
- W4304758014 hasRelatedWork W2336649003 @default.
- W4304758014 hasRelatedWork W3030927894 @default.
- W4304758014 hasRelatedWork W4229655155 @default.
- W4304758014 hasRelatedWork W4249127917 @default.
- W4304758014 hasRelatedWork W2360954726 @default.
- W4304758014 hasVolume "40" @default.
- W4304758014 isParatext "false" @default.
- W4304758014 isRetracted "false" @default.
- W4304758014 workType "article" @default.