Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304758344> ?p ?o ?g. }
- W4304758344 endingPage "1037" @default.
- W4304758344 startingPage "1017" @default.
- W4304758344 abstract "Immunotherapy has emerged as a powerful strategy for liquid tumors to overcome the limitations of conventional cancer therapies. The nanomedical delivery system offers the possibility of enhancing cancer immunotherapy and expanding it to solid tumors. Here, we discuss the applications of medical nanoparticles to improve the efficacy of immunotherapy. We first focus on nanomedical particles used in cancer immunotherapy to deliver peptide and mRNA vaccines to the lymph nodes; and the exosome-based therapeutic cancer vaccine. Next, we highlight the applications of nanomedicine in immune checkpoint therapy to prolong the therapeutic effects, enhance tumor-targeting ability, and overcome drug resistance. We also evaluate the roles of nanomedical particles in oncolytic viral treatment, enabling the systemic injection of viruses or oncolytic plasmids/oncotoxic proteins; and virus entry in a receptor-independency manner. Lastly, we focus on nanoparticles in chimeric antigen receptor (CAR) T cell therapy to engineer CAR T cells, enhancing T cell proliferation and infiltration. We envision the nanomedical particles enhancing the therapeutic effects of immunotherapy and revolutionizing cancer therapy in the foreseeable future." @default.
- W4304758344 created "2022-10-13" @default.
- W4304758344 creator A5012239261 @default.
- W4304758344 creator A5013851036 @default.
- W4304758344 creator A5061975152 @default.
- W4304758344 creator A5083410410 @default.
- W4304758344 date "2022-11-01" @default.
- W4304758344 modified "2023-10-16" @default.
- W4304758344 title "Nanomedicine for advanced cancer immunotherapy" @default.
- W4304758344 cites W1542448731 @default.
- W4304758344 cites W1574663134 @default.
- W4304758344 cites W1597938223 @default.
- W4304758344 cites W1787662247 @default.
- W4304758344 cites W1804501722 @default.
- W4304758344 cites W1862365802 @default.
- W4304758344 cites W1963706689 @default.
- W4304758344 cites W1967722242 @default.
- W4304758344 cites W1968519475 @default.
- W4304758344 cites W1968583232 @default.
- W4304758344 cites W1973071182 @default.
- W4304758344 cites W1976892064 @default.
- W4304758344 cites W1981302308 @default.
- W4304758344 cites W1982432848 @default.
- W4304758344 cites W1983438812 @default.
- W4304758344 cites W1984334584 @default.
- W4304758344 cites W1984376606 @default.
- W4304758344 cites W1984801985 @default.
- W4304758344 cites W1986580574 @default.
- W4304758344 cites W1988072378 @default.
- W4304758344 cites W1989993555 @default.
- W4304758344 cites W1990099678 @default.
- W4304758344 cites W1991968193 @default.
- W4304758344 cites W2000297273 @default.
- W4304758344 cites W2003197307 @default.
- W4304758344 cites W2004917206 @default.
- W4304758344 cites W2004979714 @default.
- W4304758344 cites W2005771030 @default.
- W4304758344 cites W2013798321 @default.
- W4304758344 cites W2016757852 @default.
- W4304758344 cites W2016829755 @default.
- W4304758344 cites W2020079079 @default.
- W4304758344 cites W2020604513 @default.
- W4304758344 cites W2021472146 @default.
- W4304758344 cites W2021520686 @default.
- W4304758344 cites W2022668894 @default.
- W4304758344 cites W2026255101 @default.
- W4304758344 cites W2030672230 @default.
- W4304758344 cites W2033999645 @default.
- W4304758344 cites W2037262542 @default.
- W4304758344 cites W2045475405 @default.
- W4304758344 cites W2046127956 @default.
- W4304758344 cites W2050002181 @default.
- W4304758344 cites W2053760636 @default.
- W4304758344 cites W2056628849 @default.
- W4304758344 cites W2057389857 @default.
- W4304758344 cites W2058940694 @default.
- W4304758344 cites W2061101944 @default.
- W4304758344 cites W2063512646 @default.
- W4304758344 cites W2064688742 @default.
- W4304758344 cites W2070722434 @default.
- W4304758344 cites W2071105928 @default.
- W4304758344 cites W2071244674 @default.
- W4304758344 cites W2072718270 @default.
- W4304758344 cites W2079852426 @default.
- W4304758344 cites W2081562047 @default.
- W4304758344 cites W2088446904 @default.
- W4304758344 cites W2096944839 @default.
- W4304758344 cites W2109653150 @default.
- W4304758344 cites W2110410873 @default.
- W4304758344 cites W2113777630 @default.
- W4304758344 cites W2113961742 @default.
- W4304758344 cites W2114245966 @default.
- W4304758344 cites W2114363080 @default.
- W4304758344 cites W2115583652 @default.
- W4304758344 cites W2115791536 @default.
- W4304758344 cites W2118561606 @default.
- W4304758344 cites W2119191289 @default.
- W4304758344 cites W2120813964 @default.
- W4304758344 cites W2121950548 @default.
- W4304758344 cites W2124427232 @default.
- W4304758344 cites W2128564429 @default.
- W4304758344 cites W2130011407 @default.
- W4304758344 cites W2130865996 @default.
- W4304758344 cites W2142447995 @default.
- W4304758344 cites W2143463421 @default.
- W4304758344 cites W2148523692 @default.
- W4304758344 cites W2154670252 @default.
- W4304758344 cites W2154740756 @default.
- W4304758344 cites W2159271973 @default.
- W4304758344 cites W2161036292 @default.
- W4304758344 cites W2162350300 @default.
- W4304758344 cites W2166022006 @default.
- W4304758344 cites W2167028666 @default.
- W4304758344 cites W2177826333 @default.
- W4304758344 cites W2197990531 @default.
- W4304758344 cites W2219535347 @default.
- W4304758344 cites W2220882815 @default.
- W4304758344 cites W2221797292 @default.