FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4304789128> ?p ?o ?g. }

• W4304789128 abstract "Objective Screening for diabetic peripheral neuropathy (DPN) is essential for early detection and timely intervention. Quantitative assessment of small nerve fiber damage is key to the early diagnosis and assessment of its progression. Corneal confocal microscopy (CCM) is a non-invasive, in-vivo diagnostic technique that provides an accurate surrogate biomarker for small-fiber neuropathy. In this novel study for the first time, we introduced CCM to primary care as a screening tool for DPN alongside retinopathy screening to assess the level of neuropathy in this novel cohort. Research design and methods 450 consecutive subjects with type 1 or type 2 diabetes attending for annual eye screening in primary care optometry settings underwent assessment with CCM to establish the prevalence of sub-clinical diabetic peripheral neuropathy. Subjects underwent assessment for neurological and ocular symptoms of diabetes and a history of diabetic foot disease, neuropathy and diabetic retinopathy (DR). Results CCM examination was completed successfully in 427 (94.9%) subjects, 22% of whom had neuropathy according to Diabetic Neuropathy Symptom (DNS) score. The prevalence of sub-clinical neuropathy as defined by abnormal corneal nerve fiber length (CNFL) was 12.9%. In the subjects with a short duration of type 2 diabetes, 9.2% had abnormal CNFL. CCM showed significant abnormalities in corneal nerve parameters in this cohort of subjects with reduction of corneal nerve fiber density (CNFD, p&lt;0.001), CNFL (p&lt;0.001) and corneal nerve branch density (CNBD, p&lt;0.001) compared to healthy subjects. In subjects who had no evidence of DR (67% of all subjects), 12.0% had abnormal CNFL. Conclusions CCM may be a sensitive biomarker for early detection and screening of DPN in primary care alongside retinopathy screening." @default.
• W4304789128 created "2022-10-13" @default.
• W4304789128 creator A5011284115 @default.
• W4304789128 creator A5014733796 @default.
• W4304789128 creator A5030922322 @default.
• W4304789128 creator A5031749184 @default.
• W4304789128 creator A5033575514 @default.
• W4304789128 creator A5072883388 @default.
• W4304789128 creator A5090718485 @default.
• W4304789128 date "2022-10-12" @default.
• W4304789128 modified "2023-10-06" @default.
• W4304789128 title "Implementation of corneal confocal microscopy for screening and early detection of diabetic neuropathy in primary care alongside retinopathy screening: Results from a feasibility study" @default.
• W4304789128 cites W1486378717 @default.
• W4304789128 cites W1854315659 @default.
• W4304789128 cites W1965139875 @default.
• W4304789128 cites W1970589776 @default.
• W4304789128 cites W1985282719 @default.
• W4304789128 cites W2025988857 @default.
• W4304789128 cites W2034210776 @default.
• W4304789128 cites W2036255272 @default.
• W4304789128 cites W2039248126 @default.
• W4304789128 cites W2044721387 @default.
• W4304789128 cites W2053006551 @default.
• W4304789128 cites W2060377359 @default.
• W4304789128 cites W2073504587 @default.
• W4304789128 cites W2075258965 @default.
• W4304789128 cites W2084817684 @default.
• W4304789128 cites W2101631478 @default.
• W4304789128 cites W2103243775 @default.
• W4304789128 cites W2108663538 @default.
• W4304789128 cites W2113599279 @default.
• W4304789128 cites W2117172569 @default.
• W4304789128 cites W2123715778 @default.
• W4304789128 cites W2123899029 @default.
• W4304789128 cites W2137347183 @default.
• W4304789128 cites W2139960926 @default.
• W4304789128 cites W2143048304 @default.
• W4304789128 cites W2146713507 @default.
• W4304789128 cites W2150666931 @default.
• W4304789128 cites W2164153016 @default.
• W4304789128 cites W2272598166 @default.
• W4304789128 cites W2320683013 @default.
• W4304789128 cites W2488953096 @default.
• W4304789128 cites W2561727131 @default.
• W4304789128 cites W2583633419 @default.
• W4304789128 cites W2590154593 @default.
• W4304789128 cites W2596954081 @default.
• W4304789128 cites W2738165667 @default.
• W4304789128 cites W2761186840 @default.
• W4304789128 cites W2796208760 @default.
• W4304789128 cites W2806995405 @default.
• W4304789128 cites W2886200465 @default.
• W4304789128 cites W2895320890 @default.
• W4304789128 cites W2900944803 @default.
• W4304789128 cites W2940749272 @default.
• W4304789128 cites W2970441691 @default.
• W4304789128 cites W3047055434 @default.
• W4304789128 cites W4212827053 @default.
• W4304789128 cites W4230007976 @default.
• W4304789128 cites W4245107010 @default.
• W4304789128 doi "https://doi.org/10.3389/fendo.2022.891575" @default.
• W4304789128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36313738" @default.
• W4304789128 hasPublicationYear "2022" @default.
• W4304789128 type Work @default.
• W4304789128 citedByCount "3" @default.
• W4304789128 countsByYear W43047891282022 @default.
• W4304789128 countsByYear W43047891282023 @default.
• W4304789128 crossrefType "journal-article" @default.
• W4304789128 hasAuthorship W4304789128A5011284115 @default.
• W4304789128 hasAuthorship W4304789128A5014733796 @default.
• W4304789128 hasAuthorship W4304789128A5030922322 @default.
• W4304789128 hasAuthorship W4304789128A5031749184 @default.
• W4304789128 hasAuthorship W4304789128A5033575514 @default.
• W4304789128 hasAuthorship W4304789128A5072883388 @default.
• W4304789128 hasAuthorship W4304789128A5090718485 @default.
• W4304789128 hasBestOaLocation W43047891281 @default.
• W4304789128 hasConcept C118487528 @default.
• W4304789128 hasConcept C118552586 @default.
• W4304789128 hasConcept C126322002 @default.
• W4304789128 hasConcept C134018914 @default.
• W4304789128 hasConcept C2776823239 @default.
• W4304789128 hasConcept C2777180221 @default.
• W4304789128 hasConcept C2778313320 @default.
• W4304789128 hasConcept C2779178840 @default.
• W4304789128 hasConcept C2779829184 @default.
• W4304789128 hasConcept C2779901536 @default.
• W4304789128 hasConcept C2780592520 @default.
• W4304789128 hasConcept C2780837183 @default.
• W4304789128 hasConcept C555293320 @default.
• W4304789128 hasConcept C71924100 @default.
• W4304789128 hasConcept C72563966 @default.
• W4304789128 hasConceptScore W4304789128C118487528 @default.
• W4304789128 hasConceptScore W4304789128C118552586 @default.
• W4304789128 hasConceptScore W4304789128C126322002 @default.
• W4304789128 hasConceptScore W4304789128C134018914 @default.
• W4304789128 hasConceptScore W4304789128C2776823239 @default.
• W4304789128 hasConceptScore W4304789128C2777180221 @default.
• W4304789128 hasConceptScore W4304789128C2778313320 @default.
• W4304789128 hasConceptScore W4304789128C2779178840 @default.
• W4304789128 hasConceptScore W4304789128C2779829184 @default.

• next