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• W4304845748 abstract "Due to its high temporal resolution and non-invasive nature, electroencephalography (EEG) is considered a method of great value for the field of auditory cognitive neuroscience. In performing source space analyses, localization accuracy poses a bottleneck, which precise forward models based on individualized attributes such as subject anatomy or electrode locations aim to overcome. Yet acquiring anatomical images or localizing EEG electrodes requires significant additional funds and processing time, making it an oftentimes inaccessible asset. Neuroscientific software offers template solutions, on which analyses can be based. For localizing the source of auditory evoked responses, we here compared the results of employing such template anatomies and electrode positions versus the subject-specific ones, as well as combinations of the two. All considered cases represented approaches commonly used in electrophysiological studies. We considered differences between two commonly used inverse solutions (dSPM, sLORETA) and targeted the primary auditory cortex; a notoriously small cortical region that is located within the lateral sulcus, thus particularly prone to errors in localization. Through systematical comparison of early evoked component metrics and spatial leakage, we assessed how the individualization steps impacted the analyses outcomes. Both electrode locations as well as subject anatomies were found to have an effect, which though varied based on the configuration considered. When comparing the inverse solutions, we moreover found that dSPM more consistently benefited from individualization of subject morphologies compared to sLORETA, suggesting it to be the better choice for auditory cortex localization." @default.
• W4304845748 created "2022-10-13" @default.
• W4304845748 creator A5053231371 @default.
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• W4304845748 date "2022-10-13" @default.
• W4304845748 modified "2023-10-14" @default.
• W4304845748 title "Effects of individualized brain anatomies and EEG electrode positions on inferred activity of the primary auditory cortex" @default.
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• W4304845748 doi "https://doi.org/10.3389/fninf.2022.970372" @default.
• W4304845748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36313125" @default.
• W4304845748 hasPublicationYear "2022" @default.
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