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- W4304890498 endingPage "108049" @default.
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- W4304890498 abstract "Bio-derived materials have long been harnessed for their potential as backbones of biodegradable constructs. With increasing understanding of organismal biochemistry and molecular genetics, scientists are now able to obtain biomaterials with properties comparable to those achieved by the petroleum industry. Poly-γ-glutamic acid (γ-PGA) is an anionic pseudopolypeptide produced and secreted by several microorganisms, especially Bacillus species. γ-PGA is polymerised via the pgs intermembrane enzymatic complex expressed by many bacteria (including GRAS member - Bacillus subtilis). γ-PGA can exist as a homopolymer of L- glutamic acid or D- glutamic acid units or it can be a co-polymer comprised of D and L enantiomers. This non-toxic polymer is highly viscous, soluble, biodegradable and biocompatible. γ-PGA is also an example of versatile chiral-polymer, a characteristic that draws great attention from the industry. Increased understanding in the correlation between microbial genetics, substrate compositions, fermentation conditions and polymeric chemical characteristics have led to bioprocess optimisation to provide cost competitive, non-petroleum-based, biodegradable solutions. This review presents detailed insights into microbial synthesis of γ-PGA and summaries current understanding of the correlation between genetic makeup of γ-PGA-producing bacteria, range of culture cultivation conditions, and physicochemical properties of this incredibly versatile biopolymer. Additionally, we hope that review provides an updated overview of findings relevant to sustainable and cost-effective biosynthesis of γ-PGA, with application in medicine, pharmacy, cosmetics, food, agriculture and for bioremediation." @default.
- W4304890498 created "2022-10-13" @default.
- W4304890498 creator A5006441316 @default.
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- W4304890498 creator A5057901351 @default.
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- W4304890498 creator A5084978266 @default.
- W4304890498 date "2022-12-01" @default.
- W4304890498 modified "2023-09-30" @default.
- W4304890498 title "Building a circular economy around poly(D/L-γ-glutamic acid)- a smart microbial biopolymer" @default.
- W4304890498 cites W133535115 @default.
- W4304890498 cites W1440059669 @default.
- W4304890498 cites W1509202041 @default.
- W4304890498 cites W1522448931 @default.
- W4304890498 cites W1584186822 @default.
- W4304890498 cites W1602619123 @default.
- W4304890498 cites W1944495115 @default.
- W4304890498 cites W1951524074 @default.
- W4304890498 cites W1959723945 @default.
- W4304890498 cites W1962450832 @default.
- W4304890498 cites W1966239112 @default.
- W4304890498 cites W1968825130 @default.
- W4304890498 cites W1970365340 @default.
- W4304890498 cites W1970695401 @default.
- W4304890498 cites W1973008729 @default.
- W4304890498 cites W1975236551 @default.
- W4304890498 cites W1976127302 @default.
- W4304890498 cites W1977366439 @default.
- W4304890498 cites W1979804738 @default.
- W4304890498 cites W1979814728 @default.
- W4304890498 cites W1980381802 @default.
- W4304890498 cites W1981523368 @default.
- W4304890498 cites W1982582935 @default.
- W4304890498 cites W1982860510 @default.
- W4304890498 cites W1983272281 @default.
- W4304890498 cites W1984800116 @default.
- W4304890498 cites W1986688681 @default.
- W4304890498 cites W1991895907 @default.
- W4304890498 cites W1994822789 @default.
- W4304890498 cites W1994863696 @default.
- W4304890498 cites W199865532 @default.
- W4304890498 cites W2000130670 @default.
- W4304890498 cites W2000996976 @default.
- W4304890498 cites W2002857853 @default.
- W4304890498 cites W2002937744 @default.
- W4304890498 cites W2003983219 @default.
- W4304890498 cites W2005556237 @default.
- W4304890498 cites W2006167503 @default.
- W4304890498 cites W2006214823 @default.
- W4304890498 cites W2012607503 @default.
- W4304890498 cites W2014467721 @default.
- W4304890498 cites W2022566464 @default.
- W4304890498 cites W2023039530 @default.
- W4304890498 cites W2023996751 @default.
- W4304890498 cites W2025056990 @default.
- W4304890498 cites W2026572966 @default.
- W4304890498 cites W2028198141 @default.
- W4304890498 cites W2031425293 @default.
- W4304890498 cites W2034815091 @default.
- W4304890498 cites W2035319066 @default.
- W4304890498 cites W2038612402 @default.
- W4304890498 cites W2038969379 @default.
- W4304890498 cites W2041421525 @default.
- W4304890498 cites W2043587098 @default.
- W4304890498 cites W2046420543 @default.
- W4304890498 cites W2048628290 @default.
- W4304890498 cites W2052597514 @default.
- W4304890498 cites W2054331052 @default.
- W4304890498 cites W2057674807 @default.
- W4304890498 cites W2063100178 @default.
- W4304890498 cites W2068272458 @default.
- W4304890498 cites W2076122189 @default.
- W4304890498 cites W2079406364 @default.
- W4304890498 cites W2083311703 @default.
- W4304890498 cites W2084074212 @default.
- W4304890498 cites W2089393267 @default.
- W4304890498 cites W2091344812 @default.
- W4304890498 cites W2101218555 @default.
- W4304890498 cites W2105512129 @default.
- W4304890498 cites W2106707530 @default.
- W4304890498 cites W2106861464 @default.
- W4304890498 cites W2124739568 @default.
- W4304890498 cites W2127577188 @default.
- W4304890498 cites W2129772846 @default.
- W4304890498 cites W2132868339 @default.
- W4304890498 cites W2133072777 @default.
- W4304890498 cites W2134020188 @default.
- W4304890498 cites W2137158805 @default.
- W4304890498 cites W2139077617 @default.
- W4304890498 cites W2140865551 @default.
- W4304890498 cites W2142135584 @default.
- W4304890498 cites W2142139001 @default.
- W4304890498 cites W2143403807 @default.
- W4304890498 cites W2143867966 @default.
- W4304890498 cites W2149443281 @default.
- W4304890498 cites W2152025026 @default.