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- W4304974982 endingPage "1163" @default.
- W4304974982 startingPage "1149" @default.
- W4304974982 abstract "Current study for the first time tested the hypothesis that during 3 days of soleus muscle unloading, calcium-dependent signaling pathways, markers of protein synthesis, and the expression of E3 ubiquitin ligases can be regulated by metformin. Treatment with metformin during unloading: prevented the decrease of p-AMPK and increase of ATP content, affected regulation of calcium-dependent signaling pathways, and attenuated an increase of critical markers of ubiquitin-proteasome pathways. Nevertheless, metformin treatment has not prevented soleus muscle atrophy." @default.
- W4304974982 created "2022-10-14" @default.
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- W4304974982 creator A5046307315 @default.
- W4304974982 date "2022-11-01" @default.
- W4304974982 modified "2023-10-05" @default.
- W4304974982 title "Metformin attenuates an increase of calcium-dependent and ubiquitin-proteasome markers in unloaded muscle" @default.
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- W4304974982 doi "https://doi.org/10.1152/japplphysiol.00415.2022" @default.
- W4304974982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36227165" @default.