FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306149502> ?p ?o ?g. }

• W4306149502 endingPage "5012" @default.
• W4306149502 startingPage "5012" @default.
• W4306149502 abstract "Background. In many malignancies, sentinel lymph node dissection (SLND) is being used as a nodal staging tool. We prospectively evaluated the diagnostic value of radio-guided sentinel lymph node (SLN) detection in patients with prostate cancer (PCa). This study aimed to investigate the reliability of the radio-guided SLN detection technique for perioperative localization of LNs metastases as well as to map lymphatic drainage patterns of the prostate. Methods. Forty-three patients with intermediate- or high-risk cN0cM0 PCa at conventional imaging underwent radical prostatectomy with modified-extended pelvic lymph node dissection (mePLND). A day before the planned surgery, a Tc-99m nanocolloid was injected into the prostate under the control of transrectal ultrasonography (TRUS). Preoperative single-photon emission computed tomography (SPECT-CT) imaging and intraoperative gamma-probe were used to identify SLNs. All positive lesions were excised, followed by mePLND. The excised lymph nodes (LNs) were then submitted for histopathological examination, which was used as a reference for the calculation of diagnostic parameters of the SLN technique for SPECT-CT and the intraoperative gamma-probe. Results. In total, 119 SLNs were detected preoperatively (SPECT-CT) and 118 intraoperatively (gamma-probe). The study revealed that both SLN detection techniques showed a sensitivity of 90% and a specificity of 6.06%. The negative predictive value (NPV) was 66.67%. SLN technique would have correctly staged nine of 10 patients, which is the same result as in the case of limited LND. However, it allowed the removal of all metastatic nodes only in four of them. SLND would have comprised 69.7% of preoperatively detected LNs, and removed 13 out of 19 positive LNs (68.42%), respectively. Conclusions. Radio-guided SLND has a low diagnostic rate and is a poor staging tool. ePLND remains the gold standard in nodal metastases assessment in PCa. Our study indicates that lymphatic drainage of the prostate and actual metastasis routes may vary significantly." @default.
• W4306149502 created "2022-10-14" @default.
• W4306149502 creator A5007819899 @default.
• W4306149502 creator A5012396827 @default.
• W4306149502 creator A5013337799 @default.
• W4306149502 creator A5019620887 @default.
• W4306149502 creator A5019862970 @default.
• W4306149502 creator A5019968775 @default.
• W4306149502 creator A5034600466 @default.
• W4306149502 creator A5045464361 @default.
• W4306149502 creator A5046580566 @default.
• W4306149502 creator A5063133885 @default.
• W4306149502 creator A5063656550 @default.
• W4306149502 creator A5068484913 @default.
• W4306149502 creator A5076785961 @default.
• W4306149502 date "2022-10-13" @default.
• W4306149502 modified "2023-10-07" @default.
• W4306149502 title "Diagnostic Value of Radio-Guided Sentinel Node Detection in Patients with Prostate Cancer Undergoing Radical Prostatectomy with Modified-Extended Lymphadenectomy" @default.
• W4306149502 cites W1978128021 @default.
• W4306149502 cites W1994437131 @default.
• W4306149502 cites W2045281091 @default.
• W4306149502 cites W2060092937 @default.
• W4306149502 cites W2073207929 @default.
• W4306149502 cites W2074621482 @default.
• W4306149502 cites W2091083791 @default.
• W4306149502 cites W2094291050 @default.
• W4306149502 cites W2269266605 @default.
• W4306149502 cites W2404828017 @default.
• W4306149502 cites W2519576613 @default.
• W4306149502 cites W2529001189 @default.
• W4306149502 cites W2566789386 @default.
• W4306149502 cites W2580862866 @default.
• W4306149502 cites W2738549467 @default.
• W4306149502 cites W2746784295 @default.
• W4306149502 cites W2904287678 @default.
• W4306149502 cites W2944084616 @default.
• W4306149502 cites W3000417394 @default.
• W4306149502 cites W3097158220 @default.
• W4306149502 cites W3112599791 @default.
• W4306149502 cites W3128646645 @default.
• W4306149502 cites W3153693580 @default.
• W4306149502 cites W3201577472 @default.
• W4306149502 cites W4226452748 @default.
• W4306149502 cites W4286701414 @default.
• W4306149502 doi "https://doi.org/10.3390/cancers14205012" @default.
• W4306149502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36291796" @default.
• W4306149502 hasPublicationYear "2022" @default.
• W4306149502 type Work @default.
• W4306149502 citedByCount "1" @default.
• W4306149502 countsByYear W43061495022023 @default.
• W4306149502 crossrefType "journal-article" @default.
• W4306149502 hasAuthorship W4306149502A5007819899 @default.
• W4306149502 hasAuthorship W4306149502A5012396827 @default.
• W4306149502 hasAuthorship W4306149502A5013337799 @default.
• W4306149502 hasAuthorship W4306149502A5019620887 @default.
• W4306149502 hasAuthorship W4306149502A5019862970 @default.
• W4306149502 hasAuthorship W4306149502A5019968775 @default.
• W4306149502 hasAuthorship W4306149502A5034600466 @default.
• W4306149502 hasAuthorship W4306149502A5045464361 @default.
• W4306149502 hasAuthorship W4306149502A5046580566 @default.
• W4306149502 hasAuthorship W4306149502A5063133885 @default.
• W4306149502 hasAuthorship W4306149502A5063656550 @default.
• W4306149502 hasAuthorship W4306149502A5068484913 @default.
• W4306149502 hasAuthorship W4306149502A5076785961 @default.
• W4306149502 hasBestOaLocation W43061495021 @default.
• W4306149502 hasConcept C121608353 @default.
• W4306149502 hasConcept C126322002 @default.
• W4306149502 hasConcept C126838900 @default.
• W4306149502 hasConcept C142724271 @default.
• W4306149502 hasConcept C2775862295 @default.
• W4306149502 hasConcept C2776235491 @default.
• W4306149502 hasConcept C2777793825 @default.
• W4306149502 hasConcept C2778660094 @default.
• W4306149502 hasConcept C2779466945 @default.
• W4306149502 hasConcept C2779720271 @default.
• W4306149502 hasConcept C2780192828 @default.
• W4306149502 hasConcept C2780212769 @default.
• W4306149502 hasConcept C2780824555 @default.
• W4306149502 hasConcept C2780849966 @default.
• W4306149502 hasConcept C2989005 @default.
• W4306149502 hasConcept C31174226 @default.
• W4306149502 hasConcept C530470458 @default.
• W4306149502 hasConcept C71924100 @default.
• W4306149502 hasConceptScore W4306149502C121608353 @default.
• W4306149502 hasConceptScore W4306149502C126322002 @default.
• W4306149502 hasConceptScore W4306149502C126838900 @default.
• W4306149502 hasConceptScore W4306149502C142724271 @default.
• W4306149502 hasConceptScore W4306149502C2775862295 @default.
• W4306149502 hasConceptScore W4306149502C2776235491 @default.
• W4306149502 hasConceptScore W4306149502C2777793825 @default.
• W4306149502 hasConceptScore W4306149502C2778660094 @default.
• W4306149502 hasConceptScore W4306149502C2779466945 @default.
• W4306149502 hasConceptScore W4306149502C2779720271 @default.
• W4306149502 hasConceptScore W4306149502C2780192828 @default.
• W4306149502 hasConceptScore W4306149502C2780212769 @default.
• W4306149502 hasConceptScore W4306149502C2780824555 @default.
• W4306149502 hasConceptScore W4306149502C2780849966 @default.
• W4306149502 hasConceptScore W4306149502C2989005 @default.

• next