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- W4306156032 abstract "Background: Deep TMS was demonstrated to be efficacious for treatment-resistant OCD in sham-controlled pilot and subsequent multicenter trials. More recently, it’s efficacy has also been demonstrated in real-world clinical practice settings in a post marketing registry study reporting a response rate of 58% after 29 sessions. However, remission rates following Deep TMS treatment have not been reported thus far. Methods: OCD post marketing registry data from 11 sites and 170 patients was revisited to reveal remission rates. Remission was defined as an endpoint Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score <12. Only patients with at least 20 treatments sessions, baseline Y-BOCS of at least 14 and at least one post-baseline Y-BOCS were included in the analysis. Results: 145 patients from 10 sites met the inclusion criteria. 46 out of those have remitted representing 31.7% remission rate. Baseline Y-BOCS and number of lifetime failed medications positively correlated with Endpoint Y-BOCS and negatively correlated with remission rates. Conclusions: Approximately a third of treatment-resistant OCD patients achieve remission following Deep TMS. Conflicts of Interest: AT has a financial interest in BrainsWay and Advanced Mental Health Care. YR is a key inventor of the Deep TMS technology and has a financial interest in BrainsWay. RG and TH has a financial interest in BrainsWay. Funding: None" @default.
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- W4306156032 date "2022-09-01" @default.
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- W4306156032 title "Remission rates following deep TMS for treatment-resistant OCD" @default.
- W4306156032 doi "https://doi.org/10.1016/j.brs.2022.07.022" @default.
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