FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306167962> ?p ?o ?g. }

• W4306167962 endingPage "204201882211271" @default.
• W4306167962 startingPage "204201882211271" @default.
• W4306167962 abstract "Context: Polycystic ovary syndrome (PCOS) is one of the commonest endocrine disorders affecting women of reproductive age, and metformin is a widely used medication in managing this condition. Aim: To review the available literature comprehensively on the therapeutic impact of metformin on the clinical and metabolic parameters of women with PCOS. Data source: We searched PubMed, MEDLINE, Scopus, Embase, Cochrane Library and the Web of Science and selected sources for grey literature from their inception to April 2020. An updated search in PubMed was performed in June 2022. Data synthesis: Two reviewers selected eligible studies and extracted data, and the review is reported following the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Results: In 24 eligible randomised controlled trials (RCTs) involving 564 participants who received metformin therapy, metformin was associated with significant reduction in body weight by 3.13 kg (95% CI: −5.33, −0.93), body mass index (BMI) by 0.82 kg/m² (95% CI: −1.22, −0.41), fasting blood glucose [standardised mean difference (SMD): −0.23; 95% CI: −0.40, −0.06], low-density lipoprotein cholesterol (LDL-C) (SMD: −0.41; 95% CI: −0.85, 0.03), total testosterone (SMD: −0.33; 95% CI: −0.49, −0.17), androstenedione (SMD: −0.45; 95% CI: −0.70, −0.20), 17-hydroxyprogesterone (17-OHP) (SMD: −0.58; 95% CI: −1.16, 0.00) and increase the likelihood of clinical pregnancy rate [odds ratio (OR): 3.00; 95% CI: 1.95, 4.59] compared with placebo. Conclusion: In women with PCOS, metformin use has shown a positive impact in reducing body weight, BMI, total testosterone, androstenedione, 17-OHP, LDL-C, fasting blood glucose and increasing the likelihood of pregnancy in women with PCOS." @default.
• W4306167962 created "2022-10-14" @default.
• W4306167962 creator A5004073760 @default.
• W4306167962 creator A5024715045 @default.
• W4306167962 creator A5031329815 @default.
• W4306167962 creator A5036163332 @default.
• W4306167962 creator A5052449640 @default.
• W4306167962 creator A5062170233 @default.
• W4306167962 creator A5064495299 @default.
• W4306167962 creator A5088604122 @default.
• W4306167962 date "2022-01-01" @default.
• W4306167962 modified "2023-09-25" @default.
• W4306167962 title "Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials" @default.
• W4306167962 cites W1515708729 @default.
• W4306167962 cites W1827907298 @default.
• W4306167962 cites W1967263394 @default.
• W4306167962 cites W1969475765 @default.
• W4306167962 cites W1971656549 @default.
• W4306167962 cites W1978918108 @default.
• W4306167962 cites W1980862973 @default.
• W4306167962 cites W1984632097 @default.
• W4306167962 cites W1985310425 @default.
• W4306167962 cites W1986856837 @default.
• W4306167962 cites W1997137520 @default.
• W4306167962 cites W2000075793 @default.
• W4306167962 cites W2000855097 @default.
• W4306167962 cites W2012438099 @default.
• W4306167962 cites W2015778467 @default.
• W4306167962 cites W2021358564 @default.
• W4306167962 cites W2024515163 @default.
• W4306167962 cites W2026413615 @default.
• W4306167962 cites W2040105472 @default.
• W4306167962 cites W2053731484 @default.
• W4306167962 cites W2063485400 @default.
• W4306167962 cites W2076863250 @default.
• W4306167962 cites W2086084736 @default.
• W4306167962 cites W2088236976 @default.
• W4306167962 cites W2091687656 @default.
• W4306167962 cites W2093049350 @default.
• W4306167962 cites W2098923148 @default.
• W4306167962 cites W2099346905 @default.
• W4306167962 cites W2102239047 @default.
• W4306167962 cites W2108906929 @default.
• W4306167962 cites W2108998486 @default.
• W4306167962 cites W2119437574 @default.
• W4306167962 cites W2122016988 @default.
• W4306167962 cites W2123925343 @default.
• W4306167962 cites W2124304641 @default.
• W4306167962 cites W2129308211 @default.
• W4306167962 cites W2132825241 @default.
• W4306167962 cites W2133783450 @default.
• W4306167962 cites W2137765752 @default.
• W4306167962 cites W2138226825 @default.
• W4306167962 cites W2138595862 @default.
• W4306167962 cites W2141923412 @default.
• W4306167962 cites W2143635979 @default.
• W4306167962 cites W2146522847 @default.
• W4306167962 cites W2154024784 @default.
• W4306167962 cites W2157301576 @default.
• W4306167962 cites W2159094112 @default.
• W4306167962 cites W2164271065 @default.
• W4306167962 cites W2165010366 @default.
• W4306167962 cites W2165523894 @default.
• W4306167962 cites W2169777843 @default.
• W4306167962 cites W2171439516 @default.
• W4306167962 cites W2186218348 @default.
• W4306167962 cites W2560296895 @default.
• W4306167962 cites W2567362164 @default.
• W4306167962 cites W2588681363 @default.
• W4306167962 cites W2795877912 @default.
• W4306167962 cites W2913484301 @default.
• W4306167962 cites W2949825098 @default.
• W4306167962 cites W2952164700 @default.
• W4306167962 cites W2978795816 @default.
• W4306167962 cites W2990092897 @default.
• W4306167962 cites W2995755060 @default.
• W4306167962 cites W2996243158 @default.
• W4306167962 cites W3036060734 @default.
• W4306167962 cites W3118615836 @default.
• W4306167962 cites W3186515993 @default.
• W4306167962 cites W3213220919 @default.
• W4306167962 cites W4200098732 @default.
• W4306167962 doi "https://doi.org/10.1177/20420188221127142" @default.
• W4306167962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36225721" @default.
• W4306167962 hasPublicationYear "2022" @default.
• W4306167962 type Work @default.
• W4306167962 citedByCount "1" @default.
• W4306167962 countsByYear W43061679622023 @default.
• W4306167962 crossrefType "journal-article" @default.
• W4306167962 hasAuthorship W4306167962A5004073760 @default.
• W4306167962 hasAuthorship W4306167962A5024715045 @default.
• W4306167962 hasAuthorship W4306167962A5031329815 @default.
• W4306167962 hasAuthorship W4306167962A5036163332 @default.
• W4306167962 hasAuthorship W4306167962A5052449640 @default.
• W4306167962 hasAuthorship W4306167962A5062170233 @default.
• W4306167962 hasAuthorship W4306167962A5064495299 @default.
• W4306167962 hasAuthorship W4306167962A5088604122 @default.
• W4306167962 hasBestOaLocation W43061679621 @default.

• next