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• W4306173775 abstract "Identification of eloquent cortices is a prerequisite for the surgical plan but may be challenging, in particular for language areas (LAs), considering the complexity of language function and organization. Electrical intracerebral stimulations (ES) during Stereo-electroencephalography are an essential tool in the localization of LAs and high frequency ES (HFS, 50 Hz) are current gold standard. Low frequencies (1 Hz) are not effective. We aim to investigate different ES frequencies for establishing their utility in localizing LAs. We implemented an observational and prospective study evaluating frequencies lower than 50 and higher than 1 Hz; indicated as “intermediate” frequencies (IFS) performed at 6, 9 and 12 Hz and lasting 15 seconds. We included ten patients and carried out a standardized protocol comparing IFS to HFS. Eighty-six ES were carried out in LAs, positive for a language interference in 61.6% without noteworthy difference between IFS and HFS. Among these, 53.3% IFS vs 21.7% HFS yielded no after-discharge. IFS were similarly effective as HFS, with lower incidence of ADs. Their longer duration facilitated more accurate clinical testing. Our results are promising, suggesting that IFS can be useful in the study of LAs." @default.
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• W4306173775 date "2022-12-01" @default.
• W4306173775 modified "2023-10-17" @default.
• W4306173775 title "Intermediate stimulation frequencies for language mapping using Stereo-EEG" @default.
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• W4306173775 doi "https://doi.org/10.1016/j.clinph.2022.10.003" @default.
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