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- W4306177614 abstract "Introduction: Incidence of infective endocarditis (IE) requiring surgical intervention is increasing. We compared outcomes and readmission in IE patients with and without known substance abuse (SA) after left-heart surgical intervention. Methods: The Nationwide Readmission Database (2016-2018) was queried and 13,994 IE patients who underwent isolated aortic or mitral repair or replacement were identified and stratified by documented elicit substance abuse. Outcomes and readmission rates were compared. Results: Of the IE cohort, SA-associated-IE (SA-IE) was present in 20.6% (2,880/13,994) of patients, and 79.4% (11,114/13,994) were non-SA-IE patients. Although SA-IE patients were younger than non-SA-IE patients (median 38 vs 58 years old, p < 0.001), had fewer comorbidities (Elixhauser score: 13 [3-22] vs 20 [11-31], IQR, p < 0.001), and experienced lower in-hospital mortality (3.3% vs 7.0%, p < 0.001), SA-IE patients had longer length of stay (26 [16-44] vs 18 [12-28] days, p < 0.001) and costlier admissions ($89,102 vs 79,321, p < 0.001). There were no differences in 30-day (19.1% vs 20.4%, p = 0.4) and 90-day (32.0% vs 30.9%, p = 0.5) readmission between SA-IE and non-SA-IE patients but increased incidence of death if readmitted (10.8% vs 5.1%, <0.001). Conclusion: SA-IE patients an increased length of stay and associated cost. Readmission in the SA-IE cohort was common, and SA-IE was associated with higher mortality on readmission. Targeted SA-IE patient follow-up strategies should try to reduce this risk." @default.
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- W4306177614 date "2022-10-17" @default.
- W4306177614 modified "2023-10-17" @default.
- W4306177614 title "The Role of Substance Abuse on Outcomes and Readmission for Left-Sided Heart Valve Surgery in Endocarditis in the US" @default.
- W4306177614 doi "https://doi.org/10.1097/01.xcs.0000895660.90891.3b" @default.
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