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- W4306179230 abstract "INTRODUCTION: The use of ketamine by emergency medical services in the prehospital setting has increased. Adverse effects of prehospital ketamine administration have not been well-established in trauma patients. The objective of this study was to evaluate the effects of prehospital ketamine on trauma patients presenting to a Level I trauma center. This study hypothesized that respiratory depression or oversedation from ketamine would increase the number of emergency department (ED) intubations. METHODS: A retrospective review of adult trauma patients receiving prehospital ketamine from 2016 to 2021 was performed. Patients with severe traumatic brain injuries were excluded. A 1:1 propensity match was performed of patients with similar demographics, injury severity, and mechanism of injury who did not receive prehospital ketamine. Univariate analyses were used for comparison. The primary outcome was the incidence of intubation in the ED (Figure).avg, average; ED, emergency department; pts, patients.RESULTS: A total of 74 patients who received prehospital ketamine were identified. The average ketamine dose was 39 mg IV and 226.4 mg IM. Of the patients, 35.1% received ketamine for pain, 29.7% for agitation. The ED intubation rate was higher in the prehospital ketamine group with 17.6% (n = 13 of 74) requiring intubation compared with 4.8% (n = 3 of 63) who did not receive ketamine (p = 0.03). Patients who required ED intubation had higher average doses of both IV/IO (37.7 ± 4.8 mg vs 55.0 ± 24.2 mg) and IM ketamine (196.4 ± 41.7 mg vs 290.0 ± 41.3 mg). CONCLUSION: This study demonstrated that prehospital ketamine increased ED intubations. Further studies are necessary to help refine prehospital protocols and allow for more efficacious use given its increasing popularity." @default.
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- W4306179230 date "2022-10-17" @default.
- W4306179230 modified "2023-09-27" @default.
- W4306179230 title "Prehospital Ketamine Administration for Trauma Patients Results in More Emergency Department Intubations" @default.
- W4306179230 doi "https://doi.org/10.1097/01.xcs.0000895304.23446.76" @default.
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