FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306249005> ?p ?o ?g. }

• W4306249005 abstract "Background Colorectal cancer (CRC) is a common neoplasm in Western countries. Prioritizing access to colonoscopy appears of critical relevance. Alarm features are considered to increase the likelihood of CRC. Our aim was to assess the diagnostic performance of alarm features for CRC diagnosis. Methods We performed a systematic review and meta-analysis of studies reporting the diagnostic accuracy of alarm features (rectal bleeding, anemia, change in bowel habit, and weight loss) for CRC, published up to September 2021. Colonoscopy was required as the reference diagnostic test. Diagnostic accuracy measures were pooled by a bivariate mixed-effects regression model. The number needed to scope (NNS; i. e. the number of patients who need to undergo colonoscopy to diagnose one CRC) according to each alarm feature was calculated. Results 31 studies with 45 100 patients (mean age 31–88 years; men 36 %–63 %) were included. The prevalence of CRC ranged from 0.2 % to 22 %. Sensitivity was suboptimal, ranging from 12.4 % for weight loss to 49 % for rectal bleeding, whereas specificity ranged from 69.8 % for rectal bleeding to 91.9 % for weight loss. Taken individually, rectal bleeding and anemia would be the only practical alarm features mandating colonoscopy (NNS 5.3 and 6.7, respectively). Conclusions When considered independently, alarm features have variable accuracy for CRC, given the high heterogeneity of study populations reflected by wide variability in CRC prevalence. Rectal bleeding and anemia are the most practical to select patients for colonoscopy. Integration of alarm features in a comprehensive evaluation of patients should be considered." @default.
• W4306249005 created "2022-10-15" @default.
• W4306249005 creator A5003597455 @default.
• W4306249005 creator A5005836246 @default.
• W4306249005 creator A5010071655 @default.
• W4306249005 creator A5010158984 @default.
• W4306249005 creator A5010708270 @default.
• W4306249005 creator A5018820955 @default.
• W4306249005 creator A5020927144 @default.
• W4306249005 creator A5025249542 @default.
• W4306249005 creator A5029208789 @default.
• W4306249005 creator A5066004697 @default.
• W4306249005 creator A5071746022 @default.
• W4306249005 creator A5073501343 @default.
• W4306249005 creator A5074927059 @default.
• W4306249005 creator A5090863427 @default.
• W4306249005 date "2022-10-14" @default.
• W4306249005 modified "2023-10-16" @default.
• W4306249005 title "Clinical value of alarm features for colorectal cancer: a meta-analysis" @default.
• W4306249005 cites W191190337 @default.
• W4306249005 cites W1967911585 @default.
• W4306249005 cites W1989785910 @default.
• W4306249005 cites W2005501262 @default.
• W4306249005 cites W2050069009 @default.
• W4306249005 cites W2088467163 @default.
• W4306249005 cites W2121833919 @default.
• W4306249005 cites W2126727011 @default.
• W4306249005 cites W2135228145 @default.
• W4306249005 cites W2139168999 @default.
• W4306249005 cites W2141089513 @default.
• W4306249005 cites W2147493587 @default.
• W4306249005 cites W2163689545 @default.
• W4306249005 cites W2166721229 @default.
• W4306249005 cites W2510086083 @default.
• W4306249005 cites W2894356359 @default.
• W4306249005 cites W2898436077 @default.
• W4306249005 cites W2934145981 @default.
• W4306249005 cites W2994714212 @default.
• W4306249005 cites W3008953081 @default.
• W4306249005 cites W3011598093 @default.
• W4306249005 cites W3026477975 @default.
• W4306249005 cites W3092657136 @default.
• W4306249005 cites W3103327164 @default.
• W4306249005 cites W3118608387 @default.
• W4306249005 cites W3128646645 @default.
• W4306249005 doi "https://doi.org/10.1055/a-1961-4266" @default.
• W4306249005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36241197" @default.
• W4306249005 hasPublicationYear "2022" @default.
• W4306249005 type Work @default.
• W4306249005 citedByCount "0" @default.
• W4306249005 crossrefType "journal-article" @default.
• W4306249005 hasAuthorship W4306249005A5003597455 @default.
• W4306249005 hasAuthorship W4306249005A5005836246 @default.
• W4306249005 hasAuthorship W4306249005A5010071655 @default.
• W4306249005 hasAuthorship W4306249005A5010158984 @default.
• W4306249005 hasAuthorship W4306249005A5010708270 @default.
• W4306249005 hasAuthorship W4306249005A5018820955 @default.
• W4306249005 hasAuthorship W4306249005A5020927144 @default.
• W4306249005 hasAuthorship W4306249005A5025249542 @default.
• W4306249005 hasAuthorship W4306249005A5029208789 @default.
• W4306249005 hasAuthorship W4306249005A5066004697 @default.
• W4306249005 hasAuthorship W4306249005A5071746022 @default.
• W4306249005 hasAuthorship W4306249005A5073501343 @default.
• W4306249005 hasAuthorship W4306249005A5074927059 @default.
• W4306249005 hasAuthorship W4306249005A5090863427 @default.
• W4306249005 hasConcept C121608353 @default.
• W4306249005 hasConcept C126322002 @default.
• W4306249005 hasConcept C159985019 @default.
• W4306249005 hasConcept C192562407 @default.
• W4306249005 hasConcept C2778248108 @default.
• W4306249005 hasConcept C2778435480 @default.
• W4306249005 hasConcept C2779119184 @default.
• W4306249005 hasConcept C526805850 @default.
• W4306249005 hasConcept C71924100 @default.
• W4306249005 hasConcept C95190672 @default.
• W4306249005 hasConceptScore W4306249005C121608353 @default.
• W4306249005 hasConceptScore W4306249005C126322002 @default.
• W4306249005 hasConceptScore W4306249005C159985019 @default.
• W4306249005 hasConceptScore W4306249005C192562407 @default.
• W4306249005 hasConceptScore W4306249005C2778248108 @default.
• W4306249005 hasConceptScore W4306249005C2778435480 @default.
• W4306249005 hasConceptScore W4306249005C2779119184 @default.
• W4306249005 hasConceptScore W4306249005C526805850 @default.
• W4306249005 hasConceptScore W4306249005C71924100 @default.
• W4306249005 hasConceptScore W4306249005C95190672 @default.
• W4306249005 hasLocation W43062490051 @default.
• W4306249005 hasLocation W43062490052 @default.
• W4306249005 hasOpenAccess W4306249005 @default.
• W4306249005 hasPrimaryLocation W43062490051 @default.
• W4306249005 hasRelatedWork W2086392903 @default.
• W4306249005 hasRelatedWork W2170272972 @default.
• W4306249005 hasRelatedWork W2353666855 @default.
• W4306249005 hasRelatedWork W2425239049 @default.
• W4306249005 hasRelatedWork W2758544941 @default.
• W4306249005 hasRelatedWork W2792729164 @default.
• W4306249005 hasRelatedWork W2966059297 @default.
• W4306249005 hasRelatedWork W3004259476 @default.
• W4306249005 hasRelatedWork W3016587774 @default.
• W4306249005 hasRelatedWork W2903040050 @default.
• W4306249005 isParatext "false" @default.

• next