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- W4306252643 abstract "Abstract Background PIENTER 3 (P3) is the third nationwide serological survey in the Netherlands, conducted in 2016/17. The overall response rate was 13.9%, following a decreasing trend in response compared to the previous two PIENTER studies (1995/1996 and 2006/2007). During P3 a non-response survey was used to investigate non-response bias. We assess P3 representativeness and potential sources of non-response bias, and trends in decreasing participation rates across all PIENTER studies. Methods P3 invitees were classified into survey response types (RTs): Full Participants (FP), Questionnaire Only (QO), Non-Response Questionnaire (NRQ) and Absolute Non-Responders (ANR). FP demographic and health indicator data were compared with Dutch national statistics, and then the RTs were compared to each other. Random Forest algorithms were used to predict an invitee’s RT. Finally, FPs from all three PIENTERs were compared to investigate the profile of national survey participants through time. Results P3 FPs were in general healthier, younger and higher educated than the Dutch population. Random forest was not able to differentiate between FPs and ANRs, but when predicting FPs from NRQs we found evidence of healthy-responder bias. Participants of the three PIENTERs were found to be similar, but we found that, in line with national trends, P3 participants were less inclined to vaccinate than previous cohorts. Discussion As vaccination coverage is high in the Netherlands, P3 remains a powerful tool to monitor population-level protection against vaccine preventable diseases (VPDs). Participants of all three PIENTERS do not differ and there can be compared through time. However, future PIENTER studies should continue to focus on improving recruitment from under-represented groups but consider alternative survey modes to improve overall response." @default.
- W4306252643 created "2022-10-15" @default.
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- W4306252643 date "2022-10-14" @default.
- W4306252643 modified "2023-10-01" @default.
- W4306252643 title "Investigating sources of non-response bias in a population-based seroprevalence study of vaccine- preventable diseases in The Netherlands" @default.
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- W4306252643 doi "https://doi.org/10.21203/rs.3.rs-2093388/v1" @default.
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