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- W4306352944 abstract "Rosai-Dorfman disease (RDD) is a type of sinus histiocytosis. It is a rare disease (1:200000), particularly in children and commonly presents with massive, painless and usually bilateral cervical lymphadenopathy along with fever and weight loss. Leukocytosis, elevated erythrocyte sedimentation rate and hypergammaglobulinemia are common. A definitive diagnosis can only be made by histological analysis of affected lymph nodes. Emperipolesis and a typical immunohistochemical pattern characterized by positivity for S-100 protein and CD68 antigen and negativity for CD1a antigen are diagnostic for RDD. Here we report a case of RDD occurring in a 10-month-old child with progressive cervical lymphadenopathy and persistent fever. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis. A watchful follow-up resulted in the resolution of fever and lymphadenopathy. J Bangladesh Coll Phys Surg 2022; 40: 299-301" @default.
- W4306352944 created "2022-10-16" @default.
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- W4306352944 date "2022-10-16" @default.
- W4306352944 modified "2023-10-18" @default.
- W4306352944 title "Rosai-Dorfman Disease: A Case Report" @default.
- W4306352944 doi "https://doi.org/10.3329/jbcps.v40i4.61894" @default.
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