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- W4306362659 abstract "Malignant peripheral nerve sheath tumor (MPNST) is a spindle cell sarcoma with poor prognosis. Although patients with neurofibromatosis type 1 (NF1) have a higher risk of MPNST, it can also occur in the sporadic setting and may rarely arise centrally within bone. In this study, we present an extremely rare case of intraosseous MPNST of the maxilla arising in a 38-year-old female with no history of NF1. Despite radical surgery and postoperative radiotherapy, the patient died due to multiple distant metastases 1 year after treatment. According to the results of the literature analysis performed in this study, maxillary MPNST cases have worse clinical outcomes than general MPNSTs. In addition, it seems that NF1 and histological necrosis are poor prognostic indicators in patients with maxillary MPNST." @default.
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- W4306362659 date "2022-12-01" @default.
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- W4306362659 title "Metformin and oral cancer: In reply with emphasis on an emerging role of an old drug in oral cancer chemoprevention" @default.
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- W4306362659 doi "https://doi.org/10.1016/j.oraloncology.2022.106196" @default.
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