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- W4306376919 endingPage "1864" @default.
- W4306376919 startingPage "1864" @default.
- W4306376919 abstract "The 3D chromatin structure within the nucleus is important for gene expression regulation and correct developmental programs. Recently, the rapid development of low-input chromatin conformation capture technologies has made it possible to study 3D chromatin structures in gametes, zygotes and early embryos in a variety of species, including flies, vertebrates and mammals. There are distinct 3D chromatin structures within the male and female gametes. Following the fertilization of male and female gametes, fertilized eggs undergo drastic epigenetic reprogramming at multi levels, including the 3D chromatin structure, to convert the terminally differentiated gamete state into the totipotent state, which can give rise to an individual. However, to what extent the 3D chromatin structure reorganization is evolutionarily conserved and what the underlying mechanisms are for the tremendous reorganization in early embryos remain elusive. Here, we review the latest findings on the 3D chromatin structure reorganization during embryogenesis, and discuss the convergent and divergent reprogramming patterns and key molecular mechanisms for the 3D chromatin structure reorganization from gametes to embryos in different species. These findings shed light on how the 3D chromatin structure reorganization contribute to embryo development in different species. The findings also indicate the role of the 3D chromatin structure on the acquisition of totipotent developmental potential." @default.
- W4306376919 created "2022-10-17" @default.
- W4306376919 creator A5061565884 @default.
- W4306376919 creator A5064271606 @default.
- W4306376919 date "2022-10-15" @default.
- W4306376919 modified "2023-10-18" @default.
- W4306376919 title "A Tremendous Reorganization Journey for the 3D Chromatin Structure from Gametes to Embryos" @default.
- W4306376919 cites W1818806520 @default.
- W4306376919 cites W1922881706 @default.
- W4306376919 cites W1963648581 @default.
- W4306376919 cites W1968065062 @default.
- W4306376919 cites W1973062929 @default.
- W4306376919 cites W1979315404 @default.
- W4306376919 cites W1982480043 @default.
- W4306376919 cites W1984236721 @default.
- W4306376919 cites W1984827465 @default.
- W4306376919 cites W2000830981 @default.
- W4306376919 cites W2006015474 @default.
- W4306376919 cites W2011457803 @default.
- W4306376919 cites W2019077723 @default.
- W4306376919 cites W2028630156 @default.
- W4306376919 cites W2029925140 @default.
- W4306376919 cites W2030846850 @default.
- W4306376919 cites W2032550070 @default.
- W4306376919 cites W2034217568 @default.
- W4306376919 cites W2036827053 @default.
- W4306376919 cites W2037818631 @default.
- W4306376919 cites W2042734558 @default.
- W4306376919 cites W2045203842 @default.
- W4306376919 cites W2047755766 @default.
- W4306376919 cites W2057061886 @default.
- W4306376919 cites W2063337177 @default.
- W4306376919 cites W2064374160 @default.
- W4306376919 cites W2064537118 @default.
- W4306376919 cites W2064727535 @default.
- W4306376919 cites W2070021921 @default.
- W4306376919 cites W2073157961 @default.
- W4306376919 cites W2073504534 @default.
- W4306376919 cites W2073747699 @default.
- W4306376919 cites W2073761355 @default.
- W4306376919 cites W2090037139 @default.
- W4306376919 cites W2097201830 @default.
- W4306376919 cites W2103410123 @default.
- W4306376919 cites W2120480931 @default.
- W4306376919 cites W2125427542 @default.
- W4306376919 cites W2135842590 @default.
- W4306376919 cites W2150731787 @default.
- W4306376919 cites W2152968621 @default.
- W4306376919 cites W2159479483 @default.
- W4306376919 cites W2161212572 @default.
- W4306376919 cites W2162362951 @default.
- W4306376919 cites W2296542523 @default.
- W4306376919 cites W2302043687 @default.
- W4306376919 cites W2401568148 @default.
- W4306376919 cites W2409806253 @default.
- W4306376919 cites W2443585466 @default.
- W4306376919 cites W2461460074 @default.
- W4306376919 cites W2519280707 @default.
- W4306376919 cites W2520701010 @default.
- W4306376919 cites W2520906511 @default.
- W4306376919 cites W2530292798 @default.
- W4306376919 cites W2549864964 @default.
- W4306376919 cites W2594764564 @default.
- W4306376919 cites W2599773520 @default.
- W4306376919 cites W2604200375 @default.
- W4306376919 cites W2734870846 @default.
- W4306376919 cites W2735035409 @default.
- W4306376919 cites W2747643030 @default.
- W4306376919 cites W2757387674 @default.
- W4306376919 cites W2761461280 @default.
- W4306376919 cites W2766284392 @default.
- W4306376919 cites W2782774915 @default.
- W4306376919 cites W2799520277 @default.
- W4306376919 cites W2806123558 @default.
- W4306376919 cites W2808165720 @default.
- W4306376919 cites W2809594440 @default.
- W4306376919 cites W2809872064 @default.
- W4306376919 cites W2810823898 @default.
- W4306376919 cites W2900649558 @default.
- W4306376919 cites W2911472928 @default.
- W4306376919 cites W2913116862 @default.
- W4306376919 cites W2914173303 @default.
- W4306376919 cites W2921600473 @default.
- W4306376919 cites W2937299982 @default.
- W4306376919 cites W2952664869 @default.
- W4306376919 cites W2971932838 @default.
- W4306376919 cites W2991248607 @default.
- W4306376919 cites W2992741119 @default.
- W4306376919 cites W2992904732 @default.
- W4306376919 cites W2994756760 @default.
- W4306376919 cites W3012994109 @default.
- W4306376919 cites W3015686080 @default.
- W4306376919 cites W3036250079 @default.
- W4306376919 cites W3038841557 @default.
- W4306376919 cites W3047847485 @default.
- W4306376919 cites W3089191828 @default.
- W4306376919 cites W3108485699 @default.
- W4306376919 cites W3114643239 @default.