FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306377107> ?p ?o ?g. }

• W4306377107 abstract "Abstract Males and females show differential patterns in connectivity in resting-state networks (RSNs) during normal aging, from early adulthood to late middle age. Age-related differences in network integration (effectiveness of specialized communication at the global network level) and segregation (functional specialization at the local level of specific brain regions) may also differ by sex. These differences may be due at least in part to endogenous hormonal fluctuation, such as that which occurs in females during midlife with the transition to menopause when levels of estrogens and progesterone drop markedly. A limited number of studies that have investigated sex differences in the action of steroid hormones in brain networks. Here we investigated how sex steroid hormones relate to age-network relationships in both males and females, with a focus on network segregation. Females displayed a significant quadratic relationship between age and network segregation for the cerebellar-basal ganglia and salience networks. In both cases, segregation was still increasing through adulthood, highest in midlife, and with a downturn thereafter. However, there were no significant relationships between sex steroid hormone levels and network segregation levels in females, and they did not exhibit significant associations between progesterone or 17β-estradiol and network segregation. Patterns of connectivity between the cerebellum and basal ganglia have been associated with cognitive performance and self-reported balance confidence in older adults. Together, these findings suggest that network segregation patterns with age in females vary by network, and that sex steroid hormones are not associated with this measure of connectivity in this cross-sectional analysis. Though this is a null effect, it remains critical for understanding the extent to which hormones relate to brain network architecture." @default.
• W4306377107 created "2022-10-17" @default.
• W4306377107 creator A5000708853 @default.
• W4306377107 creator A5015156550 @default.
• W4306377107 creator A5018238510 @default.
• W4306377107 creator A5025650418 @default.
• W4306377107 creator A5052333709 @default.
• W4306377107 creator A5052551611 @default.
• W4306377107 date "2022-10-16" @default.
• W4306377107 modified "2023-10-16" @default.
• W4306377107 title "Network Segregation in Aging Females and Evaluation of the Impact of Sex Steroid Hormones" @default.
• W4306377107 cites W1772985023 @default.
• W4306377107 cites W1924391114 @default.
• W4306377107 cites W1924727730 @default.
• W4306377107 cites W1969884618 @default.
• W4306377107 cites W1973741448 @default.
• W4306377107 cites W1976692588 @default.
• W4306377107 cites W1979406324 @default.
• W4306377107 cites W1983183519 @default.
• W4306377107 cites W1983340457 @default.
• W4306377107 cites W1989868932 @default.
• W4306377107 cites W1990392898 @default.
• W4306377107 cites W2002002593 @default.
• W4306377107 cites W2007729962 @default.
• W4306377107 cites W2019634736 @default.
• W4306377107 cites W2024287605 @default.
• W4306377107 cites W2027879303 @default.
• W4306377107 cites W2042949427 @default.
• W4306377107 cites W2045645123 @default.
• W4306377107 cites W2050282115 @default.
• W4306377107 cites W2059181515 @default.
• W4306377107 cites W2063435176 @default.
• W4306377107 cites W2072826785 @default.
• W4306377107 cites W2089572795 @default.
• W4306377107 cites W2090496772 @default.
• W4306377107 cites W2091582322 @default.
• W4306377107 cites W2109262924 @default.
• W4306377107 cites W2113314534 @default.
• W4306377107 cites W2119285123 @default.
• W4306377107 cites W2134820284 @default.
• W4306377107 cites W2144317269 @default.
• W4306377107 cites W2149463687 @default.
• W4306377107 cites W2162057258 @default.
• W4306377107 cites W2291815547 @default.
• W4306377107 cites W2510306587 @default.
• W4306377107 cites W2518313848 @default.
• W4306377107 cites W2549673192 @default.
• W4306377107 cites W2550678493 @default.
• W4306377107 cites W2611821611 @default.
• W4306377107 cites W2893411620 @default.
• W4306377107 cites W2899542570 @default.
• W4306377107 cites W2913549930 @default.
• W4306377107 cites W2950512494 @default.
• W4306377107 cites W2952826950 @default.
• W4306377107 cites W2954210335 @default.
• W4306377107 cites W2977883299 @default.
• W4306377107 cites W3038831287 @default.
• W4306377107 cites W3130580852 @default.
• W4306377107 cites W4200072053 @default.
• W4306377107 cites W4220769376 @default.
• W4306377107 cites W4229608423 @default.
• W4306377107 cites W4242289937 @default.
• W4306377107 cites W4243426848 @default.
• W4306377107 cites W4244212067 @default.
• W4306377107 cites W4293786418 @default.
• W4306377107 doi "https://doi.org/10.1101/2022.10.12.511918" @default.
• W4306377107 hasPublicationYear "2022" @default.
• W4306377107 type Work @default.
• W4306377107 citedByCount "0" @default.
• W4306377107 crossrefType "posted-content" @default.
• W4306377107 hasAuthorship W4306377107A5000708853 @default.
• W4306377107 hasAuthorship W4306377107A5015156550 @default.
• W4306377107 hasAuthorship W4306377107A5018238510 @default.
• W4306377107 hasAuthorship W4306377107A5025650418 @default.
• W4306377107 hasAuthorship W4306377107A5052333709 @default.
• W4306377107 hasAuthorship W4306377107A5052551611 @default.
• W4306377107 hasBestOaLocation W43063771071 @default.
• W4306377107 hasConcept C126322002 @default.
• W4306377107 hasConcept C134018914 @default.
• W4306377107 hasConcept C2778024521 @default.
• W4306377107 hasConcept C2778562196 @default.
• W4306377107 hasConcept C2779306644 @default.
• W4306377107 hasConcept C2779938979 @default.
• W4306377107 hasConcept C2780902042 @default.
• W4306377107 hasConcept C42407357 @default.
• W4306377107 hasConcept C71315377 @default.
• W4306377107 hasConcept C71924100 @default.
• W4306377107 hasConcept C86803240 @default.
• W4306377107 hasConceptScore W4306377107C126322002 @default.
• W4306377107 hasConceptScore W4306377107C134018914 @default.
• W4306377107 hasConceptScore W4306377107C2778024521 @default.
• W4306377107 hasConceptScore W4306377107C2778562196 @default.
• W4306377107 hasConceptScore W4306377107C2779306644 @default.
• W4306377107 hasConceptScore W4306377107C2779938979 @default.
• W4306377107 hasConceptScore W4306377107C2780902042 @default.
• W4306377107 hasConceptScore W4306377107C42407357 @default.
• W4306377107 hasConceptScore W4306377107C71315377 @default.
• W4306377107 hasConceptScore W4306377107C71924100 @default.
• W4306377107 hasConceptScore W4306377107C86803240 @default.
• W4306377107 hasLocation W43063771071 @default.

• next