Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306382234> ?p ?o ?g. }
- W4306382234 abstract "Background Raw hawthorn (RH) is a traditional Chinese medicine commonly used to treat indigestion. Charred hawthorn (CH) is obtained from RH by charring. It is reported that the effect of CH treatment on dyspepsia is stronger than RH. However, this has not been fully proven. The purpose of this study was to compare the effects of RH and CH on functional dyspepsia (FD) model rats. And contribute to the development of dietary therapy for dyspepsia. Methods SPF-grade male SD rats were divided into 5 groups: the control group, the model group, the Mos group, the RH group, and the CH group. The FD rat model was established by using the methods of water restriction, fasting, tilting cage restraint, day and night upside down, swimming, and tail damping. The body weight of rats in each group was recorded. And the gastric emptying rate, intestinal propulsive rate, and the levels of motilin (MTL), gastrin (GAS), and 5-HT in serum were compared in each group. The expression of C-kit in the stomach and small intestine of each group was compared by immunofluorescence and PCR. Results RH and CH could increase weight, improve the gastric emptying rate and intestinal propulsive rate, and promote the secretion of motilin (MTL), gastrin (GAS), and 5-HT in the serum of FD rats. RH and CH can upregulate the expression of the characteristic protein c-kit of ICC in the stomach and small intestine of FD model rats, and the effect of CH is stronger than RH. Conclusion RH and CH may increase the number of interstitial cells of Cajal (ICC) in the gastrointestinal tract by upregulating c-kit expression, thus improving gastrointestinal motility in FD model rats. And compared with RH, CH has certain advantages." @default.
- W4306382234 created "2022-10-17" @default.
- W4306382234 creator A5001621109 @default.
- W4306382234 creator A5024818901 @default.
- W4306382234 creator A5038715859 @default.
- W4306382234 creator A5044396095 @default.
- W4306382234 creator A5058696745 @default.
- W4306382234 creator A5083840942 @default.
- W4306382234 date "2022-10-17" @default.
- W4306382234 modified "2023-10-01" @default.
- W4306382234 title "Investigation of the improving effect of raw and charred hawthorn on functional dyspepsia based on interstitial cells of Cajal" @default.
- W4306382234 cites W1164166279 @default.
- W4306382234 cites W1899152401 @default.
- W4306382234 cites W1966133025 @default.
- W4306382234 cites W1991175004 @default.
- W4306382234 cites W2018695056 @default.
- W4306382234 cites W2033538743 @default.
- W4306382234 cites W2085139899 @default.
- W4306382234 cites W2099590846 @default.
- W4306382234 cites W2122234580 @default.
- W4306382234 cites W2126719655 @default.
- W4306382234 cites W2215058389 @default.
- W4306382234 cites W2427259524 @default.
- W4306382234 cites W2742717079 @default.
- W4306382234 cites W2780710542 @default.
- W4306382234 cites W2797521231 @default.
- W4306382234 cites W2889652823 @default.
- W4306382234 cites W2900705789 @default.
- W4306382234 cites W2920795385 @default.
- W4306382234 cites W2965658118 @default.
- W4306382234 cites W2967060093 @default.
- W4306382234 cites W2979399591 @default.
- W4306382234 cites W2990754338 @default.
- W4306382234 cites W2995482116 @default.
- W4306382234 cites W3006212682 @default.
- W4306382234 cites W3166555599 @default.
- W4306382234 cites W3193422000 @default.
- W4306382234 cites W3202068022 @default.
- W4306382234 cites W3214810310 @default.
- W4306382234 cites W4210962142 @default.
- W4306382234 cites W4220903417 @default.
- W4306382234 cites W4225526071 @default.
- W4306382234 doi "https://doi.org/10.3389/fsufs.2022.1010556" @default.
- W4306382234 hasPublicationYear "2022" @default.
- W4306382234 type Work @default.
- W4306382234 citedByCount "0" @default.
- W4306382234 crossrefType "journal-article" @default.
- W4306382234 hasAuthorship W4306382234A5001621109 @default.
- W4306382234 hasAuthorship W4306382234A5024818901 @default.
- W4306382234 hasAuthorship W4306382234A5038715859 @default.
- W4306382234 hasAuthorship W4306382234A5044396095 @default.
- W4306382234 hasAuthorship W4306382234A5058696745 @default.
- W4306382234 hasAuthorship W4306382234A5083840942 @default.
- W4306382234 hasBestOaLocation W43063822341 @default.
- W4306382234 hasConcept C126322002 @default.
- W4306382234 hasConcept C131793682 @default.
- W4306382234 hasConcept C134018914 @default.
- W4306382234 hasConcept C178790620 @default.
- W4306382234 hasConcept C185592680 @default.
- W4306382234 hasConcept C201539569 @default.
- W4306382234 hasConcept C204232928 @default.
- W4306382234 hasConcept C2776946213 @default.
- W4306382234 hasConcept C2776986829 @default.
- W4306382234 hasConcept C2779422922 @default.
- W4306382234 hasConcept C3020479747 @default.
- W4306382234 hasConcept C49039625 @default.
- W4306382234 hasConcept C71924100 @default.
- W4306382234 hasConcept C73546260 @default.
- W4306382234 hasConcept C90924648 @default.
- W4306382234 hasConceptScore W4306382234C126322002 @default.
- W4306382234 hasConceptScore W4306382234C131793682 @default.
- W4306382234 hasConceptScore W4306382234C134018914 @default.
- W4306382234 hasConceptScore W4306382234C178790620 @default.
- W4306382234 hasConceptScore W4306382234C185592680 @default.
- W4306382234 hasConceptScore W4306382234C201539569 @default.
- W4306382234 hasConceptScore W4306382234C204232928 @default.
- W4306382234 hasConceptScore W4306382234C2776946213 @default.
- W4306382234 hasConceptScore W4306382234C2776986829 @default.
- W4306382234 hasConceptScore W4306382234C2779422922 @default.
- W4306382234 hasConceptScore W4306382234C3020479747 @default.
- W4306382234 hasConceptScore W4306382234C49039625 @default.
- W4306382234 hasConceptScore W4306382234C71924100 @default.
- W4306382234 hasConceptScore W4306382234C73546260 @default.
- W4306382234 hasConceptScore W4306382234C90924648 @default.
- W4306382234 hasLocation W43063822341 @default.
- W4306382234 hasLocation W43063822342 @default.
- W4306382234 hasOpenAccess W4306382234 @default.
- W4306382234 hasPrimaryLocation W43063822341 @default.
- W4306382234 hasRelatedWork W2056657039 @default.
- W4306382234 hasRelatedWork W2094926990 @default.
- W4306382234 hasRelatedWork W2152793037 @default.
- W4306382234 hasRelatedWork W2335339451 @default.
- W4306382234 hasRelatedWork W2371127954 @default.
- W4306382234 hasRelatedWork W2375646530 @default.
- W4306382234 hasRelatedWork W2375846835 @default.
- W4306382234 hasRelatedWork W2417190956 @default.
- W4306382234 hasRelatedWork W2748952813 @default.
- W4306382234 hasRelatedWork W4306382234 @default.
- W4306382234 hasVolume "6" @default.
- W4306382234 isParatext "false" @default.