Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306386091> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4306386091 endingPage "2383" @default.
- W4306386091 startingPage "2375" @default.
- W4306386091 abstract "Serum Cholinesterase (CHE) levels have been found to be elevated in individuals with nephrotic syndrome (NS); nevertheless, it is unknown whether CHE can serve as a biomarker for NS diagnosis and what its diagnostic relevance is for NS in minors.In this study, 138 minors aged 1-17 years with NS were enrolled, including 101 patients with the first episode of NS and 37 patients with relapsing NS. One hundred and four minors suffering from nephritis and 109 healthy minors were included as control groups. The clinical information and laboratory data of all NS patients and the control group were obtained. Logistic regression, correlation analyses and receiver operator characteristic curve were used to examine the value of CHE for NS patients.Compared to patients diagnosed with nephritis and healthy minors in the control group, the serum CHE levels of total/first episode/relapsing NS patients were substantially higher (P < 0.05). The CHE was an independent risk predictor of total (adjusted odds ratio [OR] = 2.23, 95% confidence interval [CI]: 1.57-3.18)/first episode (adjusted OR = 4.02, 95% CI: 1.47-11.08)/relapsing (adjusted OR = 2.04, 95% CI: 1.42-2.93) NS, and was positively correlated with total cholesterol in total/first episode/relapsing NS patients, respectively. The optimal cutoff for total/first episode/relapsing NS all was 11 KU/L, but the diagnostic accuracy in first episode NS (area under the curve [AUC] = 0.96, 95% CI: 0.94-0.98) was higher than the total NS (AUC = 0.93, 95% CI: 0.91-0.96) and relapsing NS (AUC = 0.85, 95% CI: 0.78-0.92).CHE is a possible biomarker for NS and has good diagnostic accuracy for NS in minors, particularly for the first episode of NS in minors." @default.
- W4306386091 created "2022-10-17" @default.
- W4306386091 creator A5003916755 @default.
- W4306386091 creator A5085817118 @default.
- W4306386091 date "2022-10-01" @default.
- W4306386091 modified "2023-10-01" @default.
- W4306386091 title "Cholinesterase is a Potential Biomarker with High Accuracy for the Nephrotic Syndrome Diagnosis in Minors" @default.
- W4306386091 cites W1994069320 @default.
- W4306386091 cites W2011341258 @default.
- W4306386091 cites W20260963 @default.
- W4306386091 cites W2030310825 @default.
- W4306386091 cites W2053918575 @default.
- W4306386091 cites W2055178678 @default.
- W4306386091 cites W2075226611 @default.
- W4306386091 cites W2108507435 @default.
- W4306386091 cites W2139250630 @default.
- W4306386091 cites W2140684874 @default.
- W4306386091 cites W2172917810 @default.
- W4306386091 cites W2594454279 @default.
- W4306386091 cites W2619139290 @default.
- W4306386091 cites W2859836197 @default.
- W4306386091 cites W2909961594 @default.
- W4306386091 cites W2924038979 @default.
- W4306386091 cites W4226150732 @default.
- W4306386091 doi "https://doi.org/10.2147/jmdh.s379249" @default.
- W4306386091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36277118" @default.
- W4306386091 hasPublicationYear "2022" @default.
- W4306386091 type Work @default.
- W4306386091 citedByCount "0" @default.
- W4306386091 crossrefType "journal-article" @default.
- W4306386091 hasAuthorship W4306386091A5003916755 @default.
- W4306386091 hasAuthorship W4306386091A5085817118 @default.
- W4306386091 hasBestOaLocation W43063860911 @default.
- W4306386091 hasConcept C126322002 @default.
- W4306386091 hasConcept C146304588 @default.
- W4306386091 hasConcept C151956035 @default.
- W4306386091 hasConcept C156957248 @default.
- W4306386091 hasConcept C185592680 @default.
- W4306386091 hasConcept C2778930706 @default.
- W4306386091 hasConcept C2781197716 @default.
- W4306386091 hasConcept C44249647 @default.
- W4306386091 hasConcept C55493867 @default.
- W4306386091 hasConcept C58471807 @default.
- W4306386091 hasConcept C71924100 @default.
- W4306386091 hasConcept C76318530 @default.
- W4306386091 hasConcept C90924648 @default.
- W4306386091 hasConceptScore W4306386091C126322002 @default.
- W4306386091 hasConceptScore W4306386091C146304588 @default.
- W4306386091 hasConceptScore W4306386091C151956035 @default.
- W4306386091 hasConceptScore W4306386091C156957248 @default.
- W4306386091 hasConceptScore W4306386091C185592680 @default.
- W4306386091 hasConceptScore W4306386091C2778930706 @default.
- W4306386091 hasConceptScore W4306386091C2781197716 @default.
- W4306386091 hasConceptScore W4306386091C44249647 @default.
- W4306386091 hasConceptScore W4306386091C55493867 @default.
- W4306386091 hasConceptScore W4306386091C58471807 @default.
- W4306386091 hasConceptScore W4306386091C71924100 @default.
- W4306386091 hasConceptScore W4306386091C76318530 @default.
- W4306386091 hasConceptScore W4306386091C90924648 @default.
- W4306386091 hasLocation W43063860911 @default.
- W4306386091 hasLocation W43063860912 @default.
- W4306386091 hasLocation W43063860913 @default.
- W4306386091 hasLocation W43063860914 @default.
- W4306386091 hasOpenAccess W4306386091 @default.
- W4306386091 hasPrimaryLocation W43063860911 @default.
- W4306386091 hasRelatedWork W2037611947 @default.
- W4306386091 hasRelatedWork W2102477885 @default.
- W4306386091 hasRelatedWork W2122443163 @default.
- W4306386091 hasRelatedWork W2335988042 @default.
- W4306386091 hasRelatedWork W2416466220 @default.
- W4306386091 hasRelatedWork W2611007169 @default.
- W4306386091 hasRelatedWork W3132856804 @default.
- W4306386091 hasRelatedWork W3175552280 @default.
- W4306386091 hasRelatedWork W4317659509 @default.
- W4306386091 hasRelatedWork W4318821646 @default.
- W4306386091 hasVolume "Volume 15" @default.
- W4306386091 isParatext "false" @default.
- W4306386091 isRetracted "false" @default.
- W4306386091 workType "article" @default.