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• W4306386157 abstract "At mucosal surfaces, immature resident dendritic cells (DCs) and Langerhans cells (LCs) are among the first cell types to encounter and be infected by HIV-1 virus ( Ahmed et al., 2015 Ahmed Z. Kawamura T. Shimada S. Piguet V. The role of human dendritic cells in HIV-1 infection. J Invest Dermatol. 2015; 135: 1225-1233 Abstract Full Text Full Text PDF PubMed Scopus (38) Google Scholar ; Pena-Cruz et al., 2018 Pena-Cruz V. Agosto L.M. Akiyama H. Olson A. Moreau Y. Larrieux J.R. et al. HIV-1 replicates and persists in vaginal epithelial dendritic cells. J Clin Invest. 2018; 128: 3439-3444 Crossref PubMed Scopus (41) Google Scholar ). LCs and myeloid DCs can restrict early HIV-1 infection through active mechanisms of viral entry restriction owing to their primary autophagic functions ( Blanchet et al., 2010 Blanchet F.P. Moris A. Nikolic D.S. Lehmann M. Cardinaud S. Stalder R. et al. Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity. 2010; 32: 654-669 Abstract Full Text Full Text PDF PubMed Scopus (218) Google Scholar ). During early-stage infection, the recognition of virus by DCs results in the release of cytokines: IFN-stimulated genes and TGF-β have shown their contribution to the control of HIV-1 infection ( Czubala et al., 2016 Czubala M.A. Finsterbusch K. Ivory M.O. Mitchell J.P. Ahmed Z. Shimauchi T. et al. TGFbeta induces a SAMHD1-independent post-entry restriction to HIV-1 infection of human epithelial Langerhans cells. J Invest Dermatol. 2016; 136: 1981-1989 Abstract Full Text Full Text PDF PubMed Scopus (14) Google Scholar ; Soper et al., 2017 Soper A. Kimura I. Nagaoka S. Konno Y. Yamamoto K. Koyanagi Y. et al. Type I interferon responses by HIV-1 infection: association with disease progression and control. Front Immunol. 2017; 8: 1823 Crossref PubMed Scopus (47) Google Scholar ). Cell-to-cell models of early HIV-1 infection have established the role of DCs in HIV-1 transfer to T lymphocytes ( Garcia et al., 2005 Garcia E. Pion M. Pelchen-Matthews A. Collinson L. Arrighi J.F. Blot G. et al. HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. Traffic. 2005; 6: 488-501 Crossref PubMed Scopus (195) Google Scholar )." @default.
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• W4306386157 date "2023-04-01" @default.
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• W4306386157 title "Macrophage Migration Inhibitory Factor Restriction of HIV-1 Transinfection from Dendritic Cells to CD4+ T Cells through the Regulation of Autophagy" @default.
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• W4306386157 doi "https://doi.org/10.1016/j.jid.2022.09.655" @default.
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