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• W4306398984 abstract "The alkaloid Aspidocarpine was isolated from the bark of Aspidosperma desmanthum. Its structure was elucidated by the spectral data of 1H and 13C-NMR (1D and 2D) and high-resolution mass spectrometry (HRESIMS). The antihypertensive activity was investigated by intravenous infusion in Wistar rats. This alkaloid significantly reduced (p < 0.05) the systolic, median, and diastolic blood pressures of rodents, without causing motor incoordination and imbalance in the rotarod test. The results indicate that the alkaloid Aspidocarpine exerts its antihypertensive activity without causing sedation or the impairment of motor functions." @default.
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• W4306398984 date "2022-10-14" @default.
• W4306398984 modified "2023-10-15" @default.
• W4306398984 title "Antihypertensive Activity of the Alkaloid Aspidocarpine in Normotensive Wistar Rats" @default.
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• W4306398984 doi "https://doi.org/10.3390/molecules27206895" @default.
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