FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306643046> ?p ?o ?g. }

• W4306643046 endingPage "2927" @default.
• W4306643046 startingPage "2918" @default.
• W4306643046 abstract "Abrupt return to normothermia has been shown a genuine factor contributing to graft dysfunction after transplantation. This study tested the concept to mitigate reperfusion injury of liver grafts by gentle warming-up using ex vivo machine perfusion prior to reperfusion. In a single center randomized controlled study, livers were assigned to conventional static cold storage (SCS) alone or to SCS followed by 90 min of ex vivo machine perfusion including controlled oxygenated rewarming (COR) by gentle and protracted elevation of the perfusate temperature from 10°C to 20°C. Primary outcome mean peak aspartate aminotransferase (AST) was 1371 U/L (SD 2871) after SCS versus 767 U/L (SD 1157) after COR (p = 0.273). Liver function test (LiMAx) on postoperative day 1 yielded 187 μg/kg/h (SD 121) after SCS, but rose to 294 μg/kg/h (SD 106) after COR (p = 0.006). Likewise, hepatic synthesis of coagulation factor V was significantly accelerated in the COR group immediately after transplantation (103% [SD 34] vs. 66% [SD 26]; p = 0.001). Fewer severe complications (Clavien-Dindo grade ≥3b) were reported in the COR group (8) than in the SCS group (15). Rewarming/reperfusion injury of liver grafts can be safely and effectively mitigated by controlling of the rewarming kinetics prior to blood reperfusion using end-ischemic ex vivo machine perfusion after cold storage." @default.
• W4306643046 created "2022-10-18" @default.
• W4306643046 creator A5005108651 @default.
• W4306643046 creator A5019797776 @default.
• W4306643046 creator A5031120133 @default.
• W4306643046 creator A5039113931 @default.
• W4306643046 creator A5046616571 @default.
• W4306643046 creator A5054893614 @default.
• W4306643046 creator A5061830141 @default.
• W4306643046 creator A5074931342 @default.
• W4306643046 creator A5087299211 @default.
• W4306643046 date "2022-10-17" @default.
• W4306643046 modified "2023-10-18" @default.
• W4306643046 title "Controlled oxygenated rewarming as novel end‐ischemic therapy for cold stored liver grafts. A randomized controlled trial" @default.
• W4306643046 cites W1481542266 @default.
• W4306643046 cites W1516189339 @default.
• W4306643046 cites W1822152374 @default.
• W4306643046 cites W1892886372 @default.
• W4306643046 cites W1931837522 @default.
• W4306643046 cites W1970229614 @default.
• W4306643046 cites W1983803702 @default.
• W4306643046 cites W2002333200 @default.
• W4306643046 cites W2031915073 @default.
• W4306643046 cites W2044760516 @default.
• W4306643046 cites W2051008480 @default.
• W4306643046 cites W2051752183 @default.
• W4306643046 cites W2061896591 @default.
• W4306643046 cites W2064825251 @default.
• W4306643046 cites W2081213279 @default.
• W4306643046 cites W2086292351 @default.
• W4306643046 cites W2088306561 @default.
• W4306643046 cites W2095126985 @default.
• W4306643046 cites W2119363042 @default.
• W4306643046 cites W2135698835 @default.
• W4306643046 cites W2144173184 @default.
• W4306643046 cites W2153076757 @default.
• W4306643046 cites W2182459494 @default.
• W4306643046 cites W2463332837 @default.
• W4306643046 cites W2464096277 @default.
• W4306643046 cites W2523430665 @default.
• W4306643046 cites W2797665619 @default.
• W4306643046 cites W2941342405 @default.
• W4306643046 cites W3175485131 @default.
• W4306643046 cites W4200009916 @default.
• W4306643046 cites W4306643046 @default.
• W4306643046 doi "https://doi.org/10.1111/cts.13409" @default.
• W4306643046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36251938" @default.
• W4306643046 hasPublicationYear "2022" @default.
• W4306643046 type Work @default.
• W4306643046 citedByCount "7" @default.
• W4306643046 countsByYear W43066430462022 @default.
• W4306643046 countsByYear W43066430462023 @default.
• W4306643046 crossrefType "journal-article" @default.
• W4306643046 hasAuthorship W4306643046A5005108651 @default.
• W4306643046 hasAuthorship W4306643046A5019797776 @default.
• W4306643046 hasAuthorship W4306643046A5031120133 @default.
• W4306643046 hasAuthorship W4306643046A5039113931 @default.
• W4306643046 hasAuthorship W4306643046A5046616571 @default.
• W4306643046 hasAuthorship W4306643046A5054893614 @default.
• W4306643046 hasAuthorship W4306643046A5061830141 @default.
• W4306643046 hasAuthorship W4306643046A5074931342 @default.
• W4306643046 hasAuthorship W4306643046A5087299211 @default.
• W4306643046 hasBestOaLocation W43066430461 @default.
• W4306643046 hasConcept C126322002 @default.
• W4306643046 hasConcept C141071460 @default.
• W4306643046 hasConcept C144027150 @default.
• W4306643046 hasConcept C146957229 @default.
• W4306643046 hasConcept C150903083 @default.
• W4306643046 hasConcept C207001950 @default.
• W4306643046 hasConcept C26291073 @default.
• W4306643046 hasConcept C2779288732 @default.
• W4306643046 hasConcept C2779609443 @default.
• W4306643046 hasConcept C2780114680 @default.
• W4306643046 hasConcept C2911091166 @default.
• W4306643046 hasConcept C2988529969 @default.
• W4306643046 hasConcept C42219234 @default.
• W4306643046 hasConcept C541997718 @default.
• W4306643046 hasConcept C71924100 @default.
• W4306643046 hasConcept C86803240 @default.
• W4306643046 hasConceptScore W4306643046C126322002 @default.
• W4306643046 hasConceptScore W4306643046C141071460 @default.
• W4306643046 hasConceptScore W4306643046C144027150 @default.
• W4306643046 hasConceptScore W4306643046C146957229 @default.
• W4306643046 hasConceptScore W4306643046C150903083 @default.
• W4306643046 hasConceptScore W4306643046C207001950 @default.
• W4306643046 hasConceptScore W4306643046C26291073 @default.
• W4306643046 hasConceptScore W4306643046C2779288732 @default.
• W4306643046 hasConceptScore W4306643046C2779609443 @default.
• W4306643046 hasConceptScore W4306643046C2780114680 @default.
• W4306643046 hasConceptScore W4306643046C2911091166 @default.
• W4306643046 hasConceptScore W4306643046C2988529969 @default.
• W4306643046 hasConceptScore W4306643046C42219234 @default.
• W4306643046 hasConceptScore W4306643046C541997718 @default.
• W4306643046 hasConceptScore W4306643046C71924100 @default.
• W4306643046 hasConceptScore W4306643046C86803240 @default.
• W4306643046 hasIssue "12" @default.
• W4306643046 hasLocation W43066430461 @default.
• W4306643046 hasLocation W43066430462 @default.

• next