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- W4306651442 abstract "Abstract Targeted memory reactivation (TMR) during sleep enhances memory consolidation in young adults by modulating electrophysiological markers of neuroplasticity. Interestingly, older adults exhibit deficits in motor memory consolidation, an impairment that has been linked to age-related degradations in the same sleep features sensitive to TMR. We hypothesized that TMR would enhance consolidation in older adults via the modulation of these markers. Seventeen older participants were trained on a motor task involving two auditory-cued sequences. During a post-learning nap, two auditory cues were played: one associated to a learned (i.e., reactivated) sequence and one control. Performance during two delayed retests did not differ between reactivated and non-reactivated sequences. Moreover, both associated and control sounds modulated brain responses, yet there were no consistent differences between the auditory cue types. Our results collectively demonstrate that older adults do not benefit from specific reactivation of a motor memory trace by an associated auditory cue during post-learning sleep. It is possible, however, that auditory stimulation during post-learning sleep boosts motor memory consolidation in a non-specific manner." @default.
- W4306651442 created "2022-10-18" @default.
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- W4306651442 date "2022-10-17" @default.
- W4306651442 modified "2023-10-03" @default.
- W4306651442 title "Targeted memory reactivation during post-learning sleep does not enhance motor memory consolidation in older adults" @default.
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- W4306651442 doi "https://doi.org/10.1101/2022.10.13.512106" @default.
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