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- W4306702244 abstract "• Toxicological effects of polystyrene nanoparticles (NPs) on yeast cells were studied. • Cells were exposed to positively charged NPs of 100-nm diameter in NaCl solutions. • Adhesion amount of NPs to a cell and cell mortality decreased with NaCl concentration. • The lower-temperature exposure reduced adhesion amount of NPs and cell mortality. • Optimal NaCl concentration was found for yeast to survive in suspensions of NPs. We have comprehensively scrutinized the effect of NaCl salt concentration ( C NaCl = 5–600 mM) and exposure temperature ( T exp = 4 and 25 °C) on the adhesion and cytotoxicity of positively charged nanoparticles (NPs) of 100-nm diameter toward two yeast strains ( Saccharomyces cerevisiae and Schizosaccharomyces pombe ) during exposure of t exp = 0.5–24 h. On the short-time exposure toward S. cerevisiae at T exp = 25 °C, the number of the NPs adhered to a yeast cell ( N adh ) monotonically decreased with C NaCl to become negligibly small at C NaCl ≥ 150 mM. The greater value of N adh resulted in the higher cell mortality. Similar results were obtained for S. pombe at C NaCl = 5–100 mM. Interestingly, N adh for S. pombe increased with C NaCl (=100 to 600 mM), where the cells considerably covered with the NPs showed relatively low mortalities during the short-time exposure. The favorable NaCl concentration was found as C * NaCl = 150 and 100 mM for S. cerevisiae and S. pombe , respectively, to survive in the aqueous suspensions of positively charged NPs during 24 h. The lower-temperature exposure ( T exp = 4 °C) for each exposure duration caused the significantly decreasing mortality of every yeast strain at the NaCl concentrations around C * NaCl ." @default.
- W4306702244 created "2022-10-19" @default.
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- W4306702244 date "2022-11-01" @default.
- W4306702244 modified "2023-10-18" @default.
- W4306702244 title "Effect of salt concentration and exposure temperature on adhesion and cytotoxicity of positively charged nanoparticles toward yeast cells" @default.
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- W4306702244 doi "https://doi.org/10.1016/j.apt.2022.103835" @default.
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