FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306735107> ?p ?o ?g. }

• W4306735107 endingPage "100232" @default.
• W4306735107 startingPage "100232" @default.
• W4306735107 abstract "To evaluate efficacy and vision with 2 prototype myopia control soft contact lenses with noncoaxial ring-focus designs (for enhancing efficacy [EE] and enhancing vision [EV]) compared with dual-focus (DF) and single-vision (SV) designs.Multicenter, 6-month, randomized, controlled, double-masked clinical trial.One hundred ninety-nine myopic (-0.75 diopters [D] to -4.50 D) children aged 7 to 12 years.Participants were randomized with stratification into myopia control (EE, EV, or DF) or SV arms at 9 clinical sites in 3 countries. Postcycloplegia axial length (AL) and spherical equivalent autorefraction (SECAR) were measured at baseline and 26 weeks. Axial length was also measured without cycloplegia at baseline, 1, 4, 13, and 26 weeks. Progression was analyzed using linear mixed models by intention-to-treat population. Visual acuity (VA) and vision quality were monitored.Axial elongation, change in SECAR.A total of 185 subjects completed the study (n = 44, 49, 45, and 47 for EE, EV, DF, and SV, respectively). There were no serious/significant ocular adverse events. After 26 weeks, EE, EV, and DF all had statistically significantly less axial elongation than SV (unadjusted mean [standard deviation]: EE, 0.079 [0.125]; EV, 0.119 [0.101]; DF, 0.135 [0.117]; SV; 0.189 [0.121] mm). The estimated least-square mean (LSM) differences (adjusted 95% confidence interval) compared with SV were -0.105 (-0.149, -0.062), -0.063 (-0.106, -0.020), and -0.056 (-0.100, -0.013) mm for EE, EV, and DF, respectively. Enhancing efficacy alone had statistically significantly less progression of SECAR than SV (EE: -0.12 [0.27] D vs. SV: -0.35 [0.33] D; LSM difference: 0.22 D [0.09, 0.35]). Enhancing efficacy also had statistically significantly less axial elongation than DF (-0.049 mm [-0.093, -0.004]). Changes in AL and SECAR of EV and DF were not statistically different. All 3 myopia control lenses had mean VA close to 0.00 logarithm of the minimum angle of resolution (logMAR) with estimated 95% upper confidence limits <0.10 logMAR. Enhancing efficacy and DF produced similar reports of halos but more than EV and SV.The prototype contact lenses met the design intent; EE was more efficacious in slowing axial elongation than DF with comparable vision performance, whereas EV produced comparable efficacy to DF with similar vision performance to SV." @default.
• W4306735107 created "2022-10-19" @default.
• W4306735107 creator A5011141787 @default.
• W4306735107 creator A5011792514 @default.
• W4306735107 creator A5082412772 @default.
• W4306735107 date "2023-03-01" @default.
• W4306735107 modified "2023-10-12" @default.
• W4306735107 title "Randomized Trial of Soft Contact Lenses with Novel Ring Focus for Controlling Myopia Progression" @default.
• W4306735107 cites W1998396779 @default.
• W4306735107 cites W1999311530 @default.
• W4306735107 cites W2007846238 @default.
• W4306735107 cites W2012757283 @default.
• W4306735107 cites W2013386495 @default.
• W4306735107 cites W2031121840 @default.
• W4306735107 cites W2042874125 @default.
• W4306735107 cites W2045918089 @default.
• W4306735107 cites W2051483562 @default.
• W4306735107 cites W2073228888 @default.
• W4306735107 cites W2147101515 @default.
• W4306735107 cites W2162741876 @default.
• W4306735107 cites W2165318802 @default.
• W4306735107 cites W2273479788 @default.
• W4306735107 cites W2327806714 @default.
• W4306735107 cites W2328599164 @default.
• W4306735107 cites W2465095160 @default.
• W4306735107 cites W2498992379 @default.
• W4306735107 cites W2792922215 @default.
• W4306735107 cites W2917133749 @default.
• W4306735107 cites W2920216425 @default.
• W4306735107 cites W2951303995 @default.
• W4306735107 cites W2963136959 @default.
• W4306735107 cites W2980582702 @default.
• W4306735107 cites W3048606831 @default.
• W4306735107 cites W3109159961 @default.
• W4306735107 cites W3159627128 @default.
• W4306735107 cites W3162209735 @default.
• W4306735107 cites W4205775408 @default.
• W4306735107 doi "https://doi.org/10.1016/j.xops.2022.100232" @default.
• W4306735107 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36545264" @default.
• W4306735107 hasPublicationYear "2023" @default.
• W4306735107 type Work @default.
• W4306735107 citedByCount "6" @default.
• W4306735107 countsByYear W43067351072023 @default.
• W4306735107 crossrefType "journal-article" @default.
• W4306735107 hasAuthorship W4306735107A5011141787 @default.
• W4306735107 hasAuthorship W4306735107A5011792514 @default.
• W4306735107 hasAuthorship W4306735107A5082412772 @default.
• W4306735107 hasBestOaLocation W43067351071 @default.
• W4306735107 hasConcept C118487528 @default.
• W4306735107 hasConcept C126322002 @default.
• W4306735107 hasConcept C141071460 @default.
• W4306735107 hasConcept C168563851 @default.
• W4306735107 hasConcept C259533 @default.
• W4306735107 hasConcept C2777381306 @default.
• W4306735107 hasConcept C2778257484 @default.
• W4306735107 hasConcept C2781135284 @default.
• W4306735107 hasConcept C2908647359 @default.
• W4306735107 hasConcept C2986805488 @default.
• W4306735107 hasConcept C44249647 @default.
• W4306735107 hasConcept C71924100 @default.
• W4306735107 hasConcept C99454951 @default.
• W4306735107 hasConceptScore W4306735107C118487528 @default.
• W4306735107 hasConceptScore W4306735107C126322002 @default.
• W4306735107 hasConceptScore W4306735107C141071460 @default.
• W4306735107 hasConceptScore W4306735107C168563851 @default.
• W4306735107 hasConceptScore W4306735107C259533 @default.
• W4306735107 hasConceptScore W4306735107C2777381306 @default.
• W4306735107 hasConceptScore W4306735107C2778257484 @default.
• W4306735107 hasConceptScore W4306735107C2781135284 @default.
• W4306735107 hasConceptScore W4306735107C2908647359 @default.
• W4306735107 hasConceptScore W4306735107C2986805488 @default.
• W4306735107 hasConceptScore W4306735107C44249647 @default.
• W4306735107 hasConceptScore W4306735107C71924100 @default.
• W4306735107 hasConceptScore W4306735107C99454951 @default.
• W4306735107 hasIssue "1" @default.
• W4306735107 hasLocation W43067351071 @default.
• W4306735107 hasLocation W43067351072 @default.
• W4306735107 hasLocation W43067351073 @default.
• W4306735107 hasOpenAccess W4306735107 @default.
• W4306735107 hasPrimaryLocation W43067351071 @default.
• W4306735107 hasRelatedWork W1976336980 @default.
• W4306735107 hasRelatedWork W2006659773 @default.
• W4306735107 hasRelatedWork W2030135619 @default.
• W4306735107 hasRelatedWork W2083248541 @default.
• W4306735107 hasRelatedWork W2260725436 @default.
• W4306735107 hasRelatedWork W2325228635 @default.
• W4306735107 hasRelatedWork W2396091285 @default.
• W4306735107 hasRelatedWork W4223552752 @default.
• W4306735107 hasRelatedWork W202679667 @default.
• W4306735107 hasRelatedWork W2612152597 @default.
• W4306735107 hasVolume "3" @default.
• W4306735107 isParatext "false" @default.
• W4306735107 isRetracted "false" @default.
• W4306735107 workType "article" @default.