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- W4306742205 abstract "Abstract Purpose To describe the clinical and sonographic features of ovarian benign Brenner tumor (BBT) and malignant Brenner tumor (MBT), and to compare performance of four diagnostic models in differentiating them. Methods Fifteen patients with BBTs and nine patients with MBTs were retrospectively identified in our institution from January 2003 and December 2021. One ultrasound examiner categorized each mass according to ovarian-adnexal reporting and data system (O-RADS), International Ovarian Tumor Analysis (IOTA) Simple Rules Risk (SR-Risk) assessment and assessment of different neoplasias in the adnexa (ADNEX) models with/without CA125. Receiver operating characteristic curves were generated to compare diagnostic performance. Results Patients with MBT had higher CA125 serum level (62.5% vs 6.7%, P =0.009) and larger maximum diameter of lesion (89mm vs 43mm, P =0.009) than did those with BBT. BBT tended to have higher prevalence of calcifications (100% vs 55.6%, P =0.012) and acoustic shadowing (93.3% vs 33.3%, P =0.004), and lower color scores manifesting none or minimal flow (100.0% vs 22.2%, P <0.001). Areas under curves of O-RADS, IOTA SR-Risk and ADNEX models with/without CA125 were 0.896, 0.913, 0.892 and 0.896, respectively. There were no significant differences between them. Conclusion BBTs are often small solid tumors with sparse color Doppler signals, which contain calcifications with posterior acoustic shadowing. The most common pattern of MBT is a large multilocular-solid or solid mass with irregular tumor borders, and most were moderately or richly vascularized at color Doppler. These four models have excellent performance in distinguishing them." @default.
- W4306742205 created "2022-10-19" @default.
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- W4306742205 date "2022-10-18" @default.
- W4306742205 modified "2023-10-18" @default.
- W4306742205 title "Comparison of performance between O-RADS, IOTA Simple Rules Risk assessment and ADNEX model in the discrimination of ovarian Brenner tumors" @default.
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- W4306742205 doi "https://doi.org/10.21203/rs.3.rs-2160740/v1" @default.
- W4306742205 hasPublicationYear "2022" @default.
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