FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306767255> ?p ?o ?g. }

• W4306767255 endingPage "136" @default.
• W4306767255 startingPage "128" @default.
• W4306767255 abstract "Resistance to the pharmacological effect of clopidogrel in patients undergoing dual antiplatelet therapy for carotid stenting may increase the risk of periprocedural neurological events. The purpose of the study was to describe the phenomenon of clopidogrel resistance in a series of patients undergoing carotid stenting.Data of patients who consecutively underwent carotid stenting from November 2016 to December 2020 for a significant stenosis and who underwent a dual antiplatelet therapy using acetyl-salicylic acid and clopidogrel were prospectively collected. Patients who were already taking a different thienopyridine were excluded. The effectiveness of antiplatelet drugs was assessed by the impedance aggregometry test. Primary endpoint was to evaluate the incidence of clopidogrel resistance and the effectiveness of ticagrelor as alternative therapy. P values < 0.05 were considered statistically significant.Two-hundred patients (80 females, 40%) underwent stenting for carotid stenosis (94% asymptomatic). The phenomenon of clopidogrel resistance was observed in 38 patients (19%), in whom clopidogrel was replaced by ticagrelor (90 mg/bis in die) with 100% effectiveness at aggregometry test. Platelet counts was associated to clopidogrel resistance (P = 0.001). There was no stent thrombosis at 30 days, neither major hemorrhagic events; a total of 12/200 major adverse cardiovascular events occurred (6%), including 1 in the group of patients who took ticagrelor and 11 in group of patients under clopidogrel (2.6% versus 6.7%, P = 0.55).Clopidogrel was ineffective in 19% of patients undergoing carotid stenting. Platelet count seemed to affect this phenomenon. In these patients, clopidogrel was effectively replaced by ticagrelor." @default.
• W4306767255 created "2022-10-19" @default.
• W4306767255 creator A5007850230 @default.
• W4306767255 creator A5008977908 @default.
• W4306767255 creator A5036523034 @default.
• W4306767255 creator A5054080849 @default.
• W4306767255 creator A5064650496 @default.
• W4306767255 creator A5068473771 @default.
• W4306767255 creator A5077602287 @default.
• W4306767255 creator A5081146865 @default.
• W4306767255 date "2023-03-01" @default.
• W4306767255 modified "2023-10-18" @default.
• W4306767255 title "Clopidogrel Resistance and Ticagrelor Replacement in Dual Antiplatelet Therapy for Carotid Artery Stenting" @default.
• W4306767255 cites W2024115454 @default.
• W4306767255 cites W2031277082 @default.
• W4306767255 cites W2074830138 @default.
• W4306767255 cites W2083038715 @default.
• W4306767255 cites W2098118614 @default.
• W4306767255 cites W2140501627 @default.
• W4306767255 cites W2161785946 @default.
• W4306767255 cites W2207242726 @default.
• W4306767255 cites W2552989745 @default.
• W4306767255 cites W2594248026 @default.
• W4306767255 cites W2612334191 @default.
• W4306767255 cites W2745403241 @default.
• W4306767255 cites W2788989970 @default.
• W4306767255 cites W2948570007 @default.
• W4306767255 cites W2953775081 @default.
• W4306767255 cites W3027047450 @default.
• W4306767255 cites W3105351895 @default.
• W4306767255 cites W3163624623 @default.
• W4306767255 cites W3173746046 @default.
• W4306767255 cites W3207179234 @default.
• W4306767255 cites W3216813363 @default.
• W4306767255 cites W3217389542 @default.
• W4306767255 cites W4210663677 @default.
• W4306767255 doi "https://doi.org/10.1016/j.avsg.2022.09.063" @default.
• W4306767255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36270550" @default.
• W4306767255 hasPublicationYear "2023" @default.
• W4306767255 type Work @default.
• W4306767255 citedByCount "1" @default.
• W4306767255 countsByYear W43067672552023 @default.
• W4306767255 crossrefType "journal-article" @default.
• W4306767255 hasAuthorship W4306767255A5007850230 @default.
• W4306767255 hasAuthorship W4306767255A5008977908 @default.
• W4306767255 hasAuthorship W4306767255A5036523034 @default.
• W4306767255 hasAuthorship W4306767255A5054080849 @default.
• W4306767255 hasAuthorship W4306767255A5064650496 @default.
• W4306767255 hasAuthorship W4306767255A5068473771 @default.
• W4306767255 hasAuthorship W4306767255A5077602287 @default.
• W4306767255 hasAuthorship W4306767255A5081146865 @default.
• W4306767255 hasConcept C126322002 @default.
• W4306767255 hasConcept C164705383 @default.
• W4306767255 hasConcept C2777028646 @default.
• W4306767255 hasConcept C2777628954 @default.
• W4306767255 hasConcept C2777849778 @default.
• W4306767255 hasConcept C2779169563 @default.
• W4306767255 hasConcept C2780007028 @default.
• W4306767255 hasConcept C2780890252 @default.
• W4306767255 hasConcept C2781068581 @default.
• W4306767255 hasConcept C42219234 @default.
• W4306767255 hasConcept C71924100 @default.
• W4306767255 hasConceptScore W4306767255C126322002 @default.
• W4306767255 hasConceptScore W4306767255C164705383 @default.
• W4306767255 hasConceptScore W4306767255C2777028646 @default.
• W4306767255 hasConceptScore W4306767255C2777628954 @default.
• W4306767255 hasConceptScore W4306767255C2777849778 @default.
• W4306767255 hasConceptScore W4306767255C2779169563 @default.
• W4306767255 hasConceptScore W4306767255C2780007028 @default.
• W4306767255 hasConceptScore W4306767255C2780890252 @default.
• W4306767255 hasConceptScore W4306767255C2781068581 @default.
• W4306767255 hasConceptScore W4306767255C42219234 @default.
• W4306767255 hasConceptScore W4306767255C71924100 @default.
• W4306767255 hasLocation W43067672551 @default.
• W4306767255 hasLocation W43067672552 @default.
• W4306767255 hasOpenAccess W4306767255 @default.
• W4306767255 hasPrimaryLocation W43067672551 @default.
• W4306767255 hasRelatedWork W2094353400 @default.
• W4306767255 hasRelatedWork W2114290874 @default.
• W4306767255 hasRelatedWork W2117950068 @default.
• W4306767255 hasRelatedWork W2279271109 @default.
• W4306767255 hasRelatedWork W2610654024 @default.
• W4306767255 hasRelatedWork W2792749019 @default.
• W4306767255 hasRelatedWork W2805772745 @default.
• W4306767255 hasRelatedWork W2810533429 @default.
• W4306767255 hasRelatedWork W2982564899 @default.
• W4306767255 hasRelatedWork W2989021573 @default.
• W4306767255 hasVolume "90" @default.
• W4306767255 isParatext "false" @default.
• W4306767255 isRetracted "false" @default.
• W4306767255 workType "article" @default.